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Adenosine

Name: Adenosine
Description: A nucleoside that is composed of adenine and d-ribose. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter. (PubChem) Pharmacology: Adenosine is an endogenous nucleoside occurring in all cells of the body and is not chemically related to other antiarrhythmic drugs. Adenosine is indicated for the conversion to sinus rhythm of paroxysmal supraventricular tachycardia (PSVT), including that associated with accessory bypass tracts (Wolff-Parkinson-White Syndrome). Adenosine is antagonized competitively by methylxanthines such as caffeine and theophylline, and potentiated by blockers of nucleoside transport such as dipyridamole. Adenosine is not blocked by atropine. Mechanism of action: Adenosine slows conduction time through the A-V node, can interrupt the reentry pathways through the A-V node, and can restore normal sinus rhythm in patients with paroxysmal supraventricular tachycardia (PSVT), including PSVT associated with Wolff-Parkinson-White Syndrome. Drug type: Approved. Investigational. Small Molecule. Drug category: Analgesics. Anti-Arrhythmia Agents. Antiarrhythmic Agents. Cardiac drugs. Vasodilator Agents
Synonym(s): 2'-Deoxyadenosine, Adenine Deoxy Nucleoside, Adenine Deoxyribonucleoside, Adenine Deoxyribose, Adenine Nucleoside, Adenine Riboside, Adenyldeoxyriboside, Deoxyadenosine, Desoxyadenosine, MEDR-640, USAF CB-10, adenosine, Adenocard, Adenocor, Adenoscan, Adenosin, Adensoine, Boniton, Myocol, Nucleocardyl, Pallacor, Sandesin
Related to: Adenylate cyclase type 1, Adenosine A3 receptor, Tumor necrosis factor
Has role: Drug
Super-category: Molecular entity
URL: http://www.drugbank.ca/drugs/DB00640
Id: CHEBI_16335
Link to OWL / RDF: Download this content as OWL/RDF

Categories related to Adenosine

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Facts about AdenosineRDF feed
Commenttaken from DrugBank
CurationStatusuncurated  +
CuratorAb  +
DefiningCitationhttp://www.drugbank.ca/drugs/DB00640  +
DefinitionA nucleoside that is composed of adenine a A nucleoside that is composed of adenine and d-ribose. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter. (PubChem) Pharmacology: Adenosine is an endogenous nucleoside occurring in all cells of the body and is not chemically related to other antiarrhythmic drugs. Adenosine is indicated for the conversion to sinus rhythm of paroxysmal supraventricular tachycardia (PSVT), including that associated with accessory bypass tracts (Wolff-Parkinson-White Syndrome). Adenosine is antagonized competitively by methylxanthines such as caffeine and theophylline, and potentiated by blockers of nucleoside transport such as dipyridamole. Adenosine is not blocked by atropine. Mechanism of action: Adenosine slows conduction time through the A-V node, can interrupt the reentry pathways through the A-V node, and can restore normal sinus rhythm in patients with paroxysmal supraventricular tachycardia (PSVT), including PSVT associated with Wolff-Parkinson-White Syndrome. Drug type: Approved. Investigational. Small Molecule. Drug category: Analgesics. Anti-Arrhythmia Agents. Antiarrhythmic Agents. Cardiac drugs. Vasodilator Agents Agents. Cardiac drugs. Vasodilator Agents
Has roleDrug  +
IdCHEBI_16335  +
LabelAdenosine  +
ModifiedDate14 April 2014  +
RelatedToAdenylate cyclase type 1  +, Adenosine A3 receptor  +, and Tumor necrosis factor  +
SuperCategoryMolecular entity  +
Synonym2'-Deoxyadenosine  +, Adenine Deoxy Nucleoside  +, Adenine Deoxyribonucleoside  +, Adenine Deoxyribose  +, Adenine Nucleoside  +, Adenine Riboside  +, Adenyldeoxyriboside  +, Deoxyadenosine  +, Desoxyadenosine  +, MEDR-640  +, USAF CB-10  +, adenosine  +, Adenocard  +, Adenocor  +, Adenoscan  +, Adenosin  +, Adensoine  +, Boniton  +, Myocol  +, Nucleocardyl  +, Pallacor  +, and Sandesin  +