Edit PONS brain region: Category:Postsubiculum

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Definition:	Division of subicular cortex characterized by projections from the anterodorsal thalamic nucleus and to a lesser extent the anteroventral nucleus, bordered ventrally and laterally by the presubiculum and dorsally and medially by the retrosplenial granular a cortex.. The border is characterized by an abrupt change in the cyto- and chemoarchitecture
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Synonym(s):	Postsubicular cortex
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Defining Criteria	cyto-architecture myelo-architecture connectivity topography chemoarchitecture
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Cyto-architecture defining criteria	Characterized by two broad cellular layers separated by a clear lamina dissecans; each cellular layer is divided into 3 layers. The outer layer is characterized by small layer III cells orgnized in rose parallel to the pial surface, covered by a thin layer or larger, darkly stained layer II neurons grouped into clusters or island. The layer II clusters are not found in the presubiculum. At the border with the retrosplenial granular a cortex, the lamina dissecans disappears.
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Myelo-architecture defining criteria
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Connectivity defining criteria	Very weak projection to the anteroventral nucleus, compared to the presubiculum. A strong projection to the lateral dorsal nucleus of the thalamus, compared to the parasubiculum which does not project to this nucleus. Postsubiculum projects to retrosplenial cortex, primarily Rgb, while presubiculum has only a light projection to Rga and none to Rgb. All 3 subdivisions of subicular complex project to entorhinal cortex, but postsubiculum fibers terminate in layers IV-VI.
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Chemoarchitecture defining criteria	Cell islands in layer 2 do not stain for AChE, in contrast to the area surrounding the islands tha is densely stained. In Vogt silver stained material, the post subiculum is characterized by a dense fiber plexus in layer 1a and extremely few fibers in layer II in corast to the even distribution of stained fibers in layer 1-III in the presubiculum. Layer 1 is evenly stained compared to a patches of light and dark staining in the retrosplenial granular a cortex. Layer III is stained in postsubiculum but not in the retrosplenial granular a cortex.
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==Notes== This page uses this default form:[[Page has default form::PONS_brain_region]] Projection to the retrosplenial cortex organized topographically, with rostral postsubiculum projecting to rostral retrosplenial cortex; projections to the thalamus were organized topographically.

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