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Resource:Beta Cell Biology Consortium

Name: Resource:Beta Cell Biology Consortium
Description: The mission of the Beta Cell Biology Consortium (BCBC) is to facilitate interdisciplinary collaborations to advance our understanding of pancreatic islet development and function, with the goal of developing innovative therapies to correct the loss of beta cell mass in diabetes, including cell reprogramming, regeneration and replacement. Resources include anitbodies, adenoviruses, functional genomics studies, mouse ES cell lines, mouse strains, protocols, etc. New resources are encouraged and welcome.

Currently, the BCBC consists of more than 50 research laboratories, which are funded by U-01 cooperative agreements. Activities within the BCBC are overseen by both NIDDK staff members and participating scientists. A Coordinating Center located at Vanderbilt University provides the organizational infrastructure for the BCBC. Its primary objectives are to 1) facilitate interactions and communication by organizing meetings and retreats, distributing announcements, and maintaining a website with databases of vital research resources; 2) support research within the BCBC by organizing core facilities and, when necessary, developing new cores; 3) jumpstart new research by young investigators through a Pilot and Feasibility (P&F) Grant Program; and 4) bring different groups of scientists together within the BCBC through a Program of Collaborative Bridging Projects.

Many of the BCBC investigator-initiated projects involve reagent-generating activities that will benefit the larger scientific community. The combination of programs and activities that, together comprise the BCBC, should accelerate the pace of major new discoveries and progress within the field of beta cell biology.

  • BCBC Antibody Collection: The antibody catalog is available not only to BCBC investigators, but to the international research community at large, at various levels of access permissions. The BCBC will produce and maintain a list of available antibodies, and will rate the usefulness of the antibodies requested within the consortium. Antibodies will be made available through an online catalog and order form posted on the website. Custom requests can be made by filling out the 'Request a Custom Antibody' form on the website.
  • The BCBC Adenovirus Collection is a repository of replication-deficient recombinant adenoviruses. The repository is accessible through this searchable database, created and maintained by the BCBC Coordinating Center, and through which individual viruses may be ordered. Upon request, the user will receive an aliquot of viral stock that may be used for further amplification in HEK293 cells. HEK293 cells are available though the ATCC, or from the investigator's own institutional tissue culture core facility, if available.
  • Genomics Studies Collection: This collection holds studies that contain information about genes expressed in cells of the pancreas and their transcriptional regulation. Pancreatic genes were also identified by microarray analysis of pancreatic tissues.
  • The BCBC ESC Line Collection is an information management system that features the collection and dissemination of information on ESC Lines that are useful for beta cell and/or pancreatic development research. The goal of this information resource is to promote sharing these cells in an effort to facilitate collaborations by sharing reagents such as these.
  • Mouse Collection: The BCBC Mouse Collection provides for the collection and sharing of annotated information on genetically modified mouse strains that are useful for beta cell and/or pancreatic development research.
  • The BCBC Miscellaneous Resource Collection provides for the collection and sharing of annotated information that is useful for beta cell and/or pancreatic development research.
  • Protocol Collection: The BCBC Protocol Collection is a resource for the aggregation and dissemination of protocols relevant to beta cell biology.
  • TRAFEX - TRAnscription Factor EXpression survey is a searchable database of gene expression data.
Parent Organization: Vanderbilt University; Tennessee; USA
Supporting Agency: NIDDK
Related to: Resource:One Mind Biospecimen Bank Listing, US Biobank
Resource Type(s): Database, Community building portal, Data storage repository, Reagent supplier, Cell repository, Organism supplier, Experimental protocol, Data set
Keywords: Pancreatic islet, Diabetes, Mouse, Beta cell, Pancreas, Pancreatic development, Embryonic stem cell, Cell line
Grant: DK-01-014, DK-01-17, DK-01-18, DK-09-011
Abbreviation: BCBC,
Resource: Resource
URL: http://www.betacell.org/
Id: nlx_144143
Organism: Mouse, Non-human animal
Link to OWL / RDF: Download this content as OWL/RDF

Categories related to Resource:Beta Cell Biology Consortium

Resource:Integrated Animals, Resource:Integrated Manually Extracted Annotation, Resource:dkCOIN

Curation status: Curated

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Facts about Resource:Beta Cell Biology ConsortiumRDF feed
AbbrevBCBC,  +
CommentAddress:The Beta Cell Biology Consortium, Vanderbilt Center for Stem Cell Biology, 2213, Garland Avenue, 9465 MRB IV, Nashville, TN 37232-0494 Telephone: 615.936.8327 Fax: 615.322.6645
CurationStatuscurated  +
DefiningCitationhttp://www.betacell.org/  +
DefinitionThe mission of the Beta Cell Biology Conso The mission of the Beta Cell Biology Consortium (BCBC) is to facilitate interdisciplinary collaborations to advance our understanding of pancreatic islet development and function, with the goal of developing innovative therapies to correct the loss of beta cell mass in diabetes, including cell reprogramming, regeneration and replacement. Resources include anitbodies, adenoviruses, functional genomics studies, mouse ES cell lines, mouse strains, protocols, etc. New resources are encouraged and welcome.

Currently, the BCBC consists of more than 50 research laboratories, which are funded by U-01 cooperative agreements. Activities within the BCBC are overseen by both NIDDK staff members and participating scientists. A Coordinating Center located at Vanderbilt University provides the organizational infrastructure for the BCBC. Its primary objectives are to 1) facilitate interactions and communication by organizing meetings and retreats, distributing announcements, and maintaining a website with databases of vital research resources; 2) support research within the BCBC by organizing core facilities and, when necessary, developing new cores; 3) jumpstart new research by young investigators through a Pilot and Feasibility (P&F) Grant Program; and 4) bring different groups of scientists together within the BCBC through a Program of Collaborative Bridging Projects.

Many of the BCBC investigator-initiated projects involve reagent-generating activities that will benefit the larger scientific community. The combination of programs and activities that, together comprise the BCBC, should accelerate the pace of major new discoveries and progress within the field of beta cell biology.

  • BCBC Antibody Collection: The antibody catalog is available not only to BCBC investigators, but to the international research community at large, at various levels of access permissions. The BCBC will produce and maintain a list of available antibodies, and will rate the usefulness of the antibodies requested within the consortium. Antibodies will be made available through an online catalog and order form posted on the website. Custom requests can be made by filling out the 'Request a Custom Antibody' form on the website.
  • The BCBC Adenovirus Collection is a repository of replication-deficient recombinant adenoviruses. The repository is accessible through this searchable database, created and maintained by the BCBC Coordinating Center, and through which individual viruses may be ordered. Upon request, the user will receive an aliquot of viral stock that may be used for further amplification in HEK293 cells. HEK293 cells are available though the ATCC, or from the investigator's own institutional tissue culture core facility, if available.
  • Genomics Studies Collection: This collection holds studies that contain information about genes expressed in cells of the pancreas and their transcriptional regulation. Pancreatic genes were also identified by microarray analysis of pancreatic tissues.
  • The BCBC ESC Line Collection is an information management system that features the collection and dissemination of information on ESC Lines that are useful for beta cell and/or pancreatic development research. The goal of this information resource is to promote sharing these cells in an effort to facilitate collaborations by sharing reagents such as these.
  • Mouse Collection: The BCBC Mouse Collection provides for the collection and sharing of annotated information on genetically modified mouse strains that are useful for beta cell and/or pancreatic development research.
  • The BCBC Miscellaneous Resource Collection provides for the collection and sharing of annotated information that is useful for beta cell and/or pancreatic development research.
  • Protocol Collection: The BCBC Protocol Collection is a resource for the aggregation and dissemination of protocols relevant to beta cell biology.
  • TRAFEX - TRAnscription Factor EXpression survey is a searchable database of gene expression data. archable database of gene expression data.
ExampleImageBCBC.PNG  +
GrantCategory:DK-01-014   +, Category:DK-01-17   +, Category:DK-01-18   +, and Category:DK-09-011   +
Has default formThis property is a special property in this wiki.Resource  +
Has roleDatabase  +, Community building portal  +, Data storage repository  +, Reagent supplier  +, Cell repository  +, Organism supplier  +, Experimental protocol  +, and Data set  +
Idnlx_144143  +
Is part ofVanderbilt University; Tennessee; USA  +
KeywordsPancreatic islet  +, Diabetes  +, Mouse  +, Beta cell  +, Pancreas  +, Pancreatic development  +, Embryonic stem cell  +, and Cell line  +
LabelResource:Beta Cell Biology Consortium  +
ModifiedDate21 June 2012  +
Page has default formThis property is a special property in this wiki.Resource  +
RelatedToResource:One Mind Biospecimen Bank Listing  +, and US Biobank  +
SpeciesMouse  +, and Non-human animal  +
SuperCategoryResource  +
Supporting AgencyNIDDK  +