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5-HT1D receptor

Name: 5-HT1D receptor
Description: A serotonin receptor subtype that is localized to the caudate nucleus; putamen; the nucleus accumbens; the hippocampus, and the raphe nuclei. It plays a role as a terminal autoreceptor that regulates the rate of serotonin release from nerve endings. This serotonin receptor subtype is closely related to and has similar drug binding properties as the 5-HT1B receptor, but is expressed at low levels. It is particularly sensitive to the agonist sumatripan and may be involved in mediating the drug's antimigrane effect.
Synonym(s): 5 HT1D Receptor; 5 HT1DALPHA RECEPT; 5 Hydroxytryptamine1D Receptor; 5-HT1D Receptor; 5-HT1Dalpha Receptor; 5-Hydroxytryptamine1D Receptor; Receptor, 5-HT1D; Receptor, 5-Hydroxytryptamine1D; Receptor, Serotonin 1D; Receptor, Serotonin 1Dalpha; Receptors, Serotonin 1D; Serotonin 01 D receptor; Serotonin 1D Alpha Receptor; Serotonin 1D Receptor; Serotonin 1D Receptors; Serotonin 1Dalpha Receptor
Has role: 5-HT Receptor
Super-category: Serotonin G-protein coupled receptor
Id: nifext_6164
Link to OWL / RDF: Download this content as OWL/RDF


MSH: D044346

Contributors

Admin, Bandrow, Nifbot2

Subcategories

This category has the following 3 subcategories, out of 3 total.

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Created19 September 2007  +
CurationStatusuncurated  +
DefinitionA serotonin receptor subtype that is local A serotonin receptor subtype that is localized to the caudate nucleus; putamen; the nucleus accumbens; the hippocampus, and the raphe nuclei. It plays a role as a terminal autoreceptor that regulates the rate of serotonin release from nerve endings. This serotonin receptor subtype is closely related to and has similar drug binding properties as the 5-HT1B receptor, but is expressed at low levels. It is particularly sensitive to the agonist sumatripan and may be involved in mediating the drug's antimigrane effect. n mediating the drug's antimigrane effect.
Has role5-HT Receptor  +
Idnifext_6164  +
Label5-HT1D receptor  +
ModifiedDate13 July 2010  +
SuperCategorySerotonin G-protein coupled receptor  +
Synonym5 HT1D Receptor; 5 HT1DALPHA RECEPT; 5 Hydroxytryptamine1D Receptor; 5-HT1D Receptor; 5-HT1Dalpha Receptor; 5-Hydroxytryptamine1D Receptor; Receptor  +, 5-HT1D; Receptor  +, 5-Hydroxytryptamine1D; Receptor  +, Serotonin 1D; Receptor  +, Serotonin 1Dalpha; Receptors  +, and Serotonin 1D; Serotonin 01 D receptor; Serotonin 1D Alpha Receptor; Serotonin 1D Receptor; Serotonin 1D Receptors; Serotonin 1Dalpha Receptor  +