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5-HT1D receptor

Name: 5-HT1D receptor
Description: A serotonin receptor subtype that is localized to the caudate nucleus; putamen; the nucleus accumbens; the hippocampus, and the raphe nuclei. It plays a role as a terminal autoreceptor that regulates the rate of serotonin release from nerve endings. This serotonin receptor subtype is closely related to and has similar drug binding properties as the 5-HT1B receptor, but is expressed at low levels. It is particularly sensitive to the agonist sumatripan and may be involved in mediating the drug's antimigrane effect.
Synonym(s): 5 HT1D Receptor; 5 HT1DALPHA RECEPT; 5 Hydroxytryptamine1D Receptor; 5-HT1D Receptor; 5-HT1Dalpha Receptor; 5-Hydroxytryptamine1D Receptor; Receptor, 5-HT1D; Receptor, 5-Hydroxytryptamine1D; Receptor, Serotonin 1D; Receptor, Serotonin 1Dalpha; Receptors, Serotonin 1D; Serotonin 01 D receptor; Serotonin 1D Alpha Receptor; Serotonin 1D Receptor; Serotonin 1D Receptors; Serotonin 1Dalpha Receptor
Has role: 5-HT Receptor
Super-category: Serotonin G-protein coupled receptor
*Id: nifext_6164
Link to OWL / RDF: Download this content as OWL/RDF


MSH: D044346

Contributors

Admin, Bandrow, Nifbot2

Subcategories

This category has the following 3 subcategories, out of 3 total.

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*Note: Neurolex imports many terms and their ids from existing community ontologies, e.g., the Gene Ontology. Neurolex, however, is a dynamic site and any content beyond the identifier should not be presumed to reflect the content or views of the source ontology. Users should consult with the authoritative source for each ontology for current information.

Facts about 5-HT1D receptorRDF feed
Created19 September 2007  +
CurationStatusuncurated  +
DefinitionA serotonin receptor subtype that is local A serotonin receptor subtype that is localized to the caudate nucleus; putamen; the nucleus accumbens; the hippocampus, and the raphe nuclei. It plays a role as a terminal autoreceptor that regulates the rate of serotonin release from nerve endings. This serotonin receptor subtype is closely related to and has similar drug binding properties as the 5-HT1B receptor, but is expressed at low levels. It is particularly sensitive to the agonist sumatripan and may be involved in mediating the drug's antimigrane effect. n mediating the drug's antimigrane effect.
Has role5-HT Receptor  +
Idnifext_6164  +
Label5-HT1D receptor  +
ModifiedDate13 July 2010  +
SuperCategorySerotonin G-protein coupled receptor  +
Synonym5 HT1D Receptor; 5 HT1DALPHA RECEPT; 5 Hydroxytryptamine1D Receptor; 5-HT1D Receptor; 5-HT1Dalpha Receptor; 5-Hydroxytryptamine1D Receptor; Receptor  +, 5-HT1D; Receptor  +, 5-Hydroxytryptamine1D; Receptor  +, Serotonin 1D; Receptor  +, Serotonin 1Dalpha; Receptors  +, and Serotonin 1D; Serotonin 01 D receptor; Serotonin 1D Alpha Receptor; Serotonin 1D Receptor; Serotonin 1D Receptors; Serotonin 1Dalpha Receptor  +