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Acetophenazine

Name: Acetophenazine
Description: Acetophenazine is an antipsychotic drug of moderate-potency. It is used in the treatment of disorganized and psychotic thinking. It is also used to help treat false perceptions (e.g. hallucinations or delusions). It primarily targets the dopamine D2 receptor. Pharmacology: Acetophenzine is a phenothiazine antipsychotic intended for the management of schizophrenia and other psychotic disorders. Mechanism of action: Acetophenazine blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; depresses the release of hypothalamic and hypophyseal hormones and is believed to depress the reticular activating system thus affecting basal metabolism, body temperature, wakefulness, vasomotor tone, and emesis. Drug type: Approved. Small Molecule. Drug category: Antipsychotics
Synonym(s): Tindal
Related to: D(1A) dopamine receptor, D(2) dopamine receptor
Has role: Drug, Antipsychotic drug
Super-category: Molecular entity
URL: http://www.drugbank.ca/drugs/DB01063
Id: CHEBI: 2401
Link to OWL / RDF: Download this content as OWL/RDF


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Facts about AcetophenazineRDF feed
Commenttaken from DrugBank
CurationStatusuncurated  +
CuratorAb  +
DefiningCitationhttp://www.drugbank.ca/drugs/DB01063  +
DefinitionAcetophenazine is an antipsychotic drug of Acetophenazine is an antipsychotic drug of moderate-potency. It is used in the treatment of disorganized and psychotic thinking. It is also used to help treat false perceptions (e.g. hallucinations or delusions). It primarily targets the dopamine D2 receptor. Pharmacology: Acetophenzine is a phenothiazine antipsychotic intended for the management of schizophrenia and other psychotic disorders. Mechanism of action: Acetophenazine blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; depresses the release of hypothalamic and hypophyseal hormones and is believed to depress the reticular activating system thus affecting basal metabolism, body temperature, wakefulness, vasomotor tone, and emesis. Drug type: Approved. Small Molecule. Drug category: Antipsychotics ll Molecule. Drug category: Antipsychotics
Has roleDrug  +, and Antipsychotic drug  +
IdCHEBI: 2401  +
LabelAcetophenazine  +
ModifiedDate14 April 2014  +
RelatedToD(1A) dopamine receptor  +, and D(2) dopamine receptor  +
SuperCategoryMolecular entity  +
SynonymTindal  +