From NeuroLex
Acetophenazine
| Name: | Acetophenazine |
| Description: | Acetophenazine is an antipsychotic drug of moderate-potency. It is used in the treatment of disorganized and psychotic thinking. It is also used to help treat false perceptions (e.g. hallucinations or delusions). It primarily targets the dopamine D2 receptor. Pharmacology: Acetophenzine is a phenothiazine antipsychotic intended for the management of schizophrenia and other psychotic disorders. Mechanism of action: Acetophenazine blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; depresses the release of hypothalamic and hypophyseal hormones and is believed to depress the reticular activating system thus affecting basal metabolism, body temperature, wakefulness, vasomotor tone, and emesis. Drug type: Approved. Small Molecule. Drug category: Antipsychotics |
| Synonym(s): | Tindal |
| Related to: | D(1A) dopamine receptor, D(2) dopamine receptor |
| Has role: | Drug, Antipsychotic drug |
| Super-category: | Molecule |
| URL: | http://www.drugbank.ca/drugs/DB01063 |
| Id: | CHEBI: 2401 |
| Link to OWL / RDF: | Download this content as OWL/RDF |
Facts about AcetophenazineRDF feed
| Comment | taken from DrugBank |
| CurationStatus | uncurated + |
| Curator | Ab + |
| DefiningCitation | http://www.drugbank.ca/drugs/DB01063 + |
| Definition | Acetophenazine is an antipsychotic drug of … Acetophenazine is an antipsychotic drug of moderate-potency. It is used in the treatment of disorganized and psychotic thinking. It is also used to help treat false perceptions (e.g. hallucinations or delusions). It primarily targets the dopamine D2 receptor. Pharmacology: Acetophenzine is a phenothiazine antipsychotic intended for the management of schizophrenia and other psychotic disorders. Mechanism of action: Acetophenazine blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; depresses the release of hypothalamic and hypophyseal hormones and is believed to depress the reticular activating system thus affecting basal metabolism, body temperature, wakefulness, vasomotor tone, and emesis. Drug type: Approved. Small Molecule. Drug category: Antipsychotics ll Molecule. Drug category: Antipsychotics |
| Has role | Drug +, and Antipsychotic drug + |
| Id | CHEBI: 2401 + |
| Label | Acetophenazine + |
| ModifiedDate | warning.pngThe date "2012-2-29" was not understood. |
| RelatedTo | D(1A) dopamine receptor +, and D(2) dopamine receptor + |
| SuperCategory | Molecule + |
| Synonym | Tindal + |




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