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Alpha2A receptor

Name: Alpha2A receptor
Description: Alpha adrenergic receptor that is found in platelets and has a low affinity for prazosin. Alpha-2-adrenergic receptors include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mice revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2A subtype inhibited transmitter release at high stimulation frequencies. (Adapted from Entrez Gene).
Synonym(s): alpha2A; alpha 2A; A2A; Alpha-2 adrenergic receptor subtype C10; Alpha-2A adrenoceptor; Alpha-2A adrenoreceptor; Alpha-2AAR; Alpha-2A adrenergic receptor, α2A adrenoreceptor, ADRA2A
Abbreviation: A2AR
Is part of: Catecholamine system, Adrenergic system, Noradrenergic system
Has role: Adrenoceptor receptor, Neurotransmitter Receptor, G-protein coupled receptor
Super-category: Protein
URL: Entrez Gene
Id: nifext_6235
PMID: PMID 7938162
Related to: Epinephrine, Norepinephrine
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Categories related to Alpha2A receptor

Amitriptyline, Amphetamine, Apraclonidine, Benzphetamine, Bethanidine, Brimonidine, Clonidine, Dexmedetomidine, Dipivefrin, Epinastine, Ergotamine, Fenoldopam, Guanabenz, Guanadrel Sulfate, Guanethidine, Guanfacine, Methyldopa, Mirtazapine, Norepinephrine, Oxymetazoline, Phentolamine, Phenylpropanolamine, Pseudoephedrine, Tizanidine, Trazodone, Yohimbine


MSH:C100639

Subcategories

This category has the following 3 subcategories, out of 3 total.

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Facts about Alpha2A receptorRDF feed
AbbrevA2AR  +
Created19 September 2007  +
CurationStatusuncurated  +
DefiningCitationEntrez Gene  +
DefinitionAlpha adrenergic receptor that is found in Alpha adrenergic receptor that is found in platelets and has a low affinity for prazosin. Alpha-2-adrenergic receptors include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mice revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2A subtype inhibited transmitter release at high stimulation frequencies. (Adapted from Entrez Gene). n frequencies. (Adapted from Entrez Gene).
Has roleAdrenoceptor receptor  +, Neurotransmitter Receptor  +, and G-protein coupled receptor  +
Idnifext_6235  +
Is part ofCatecholamine system  +, Adrenergic system  +, and Noradrenergic system  +
LabelAlpha2A receptor  +
ModifiedDate13 July 2010  +
PMID7938162  +
RelatedToEpinephrine  +, and Norepinephrine  +
SuperCategoryProtein  +
Synonymalpha2A; alpha 2A; A2A; Alpha-2 adrenergic receptor subtype C10; Alpha-2A adrenoceptor; Alpha-2A adrenoreceptor; Alpha-2AAR; Alpha-2A adrenergic receptor  +, α2A adrenoreceptor  +, and ADRA2A  +