From NeuroLex
Alpha2A receptor
| Name: | Alpha2A receptor |
| Description: | Alpha adrenergic receptor that is found in platelets and has a low affinity for prazosin. Alpha-2-adrenergic receptors include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mice revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2A subtype inhibited transmitter release at high stimulation frequencies. (Adapted from Entrez Gene). |
| Synonym(s): | alpha2A; alpha 2A; A2A; Alpha-2 adrenergic receptor subtype C10; Alpha-2A adrenoceptor; Alpha-2A adrenoreceptor; Alpha-2AAR; Alpha-2A adrenergic receptor, α2A adrenoreceptor, ADRA2A |
| Is part of: | Catecholamine system, Adrenergic system, Noradrenergic system |
| Related to: | Epinephrine, Norepinephrine |
| Has role: | Adrenoceptor receptor, Neurotransmitter Receptor, G-protein coupled receptor |
| Abbreviation: | A2AR |
| Super-category: | Protein |
| URL: | Entrez Gene |
| PMID: | PMID 7938162 |
| Id: | nifext_6235 |
| Link to OWL / RDF: | Download this content as OWL/RDF |
Categories related to Alpha2A receptor
Amitriptyline, Amphetamine, Apraclonidine, Benzphetamine, Bethanidine, Brimonidine, Clonidine, Dexmedetomidine, Dipivefrin, Epinastine, Ergotamine, Fenoldopam, Guanabenz, Guanadrel Sulfate, Guanethidine, Guanfacine, Methyldopa, Mirtazapine, Norepinephrine, Oxymetazoline, Phentolamine, Phenylpropanolamine, Pseudoephedrine, Tizanidine, Trazodone, Yohimbine
MSH:C100639
Subcategories
This category has the following 3 subcategories, out of 3 total.
A
Facts about Alpha2A receptorRDF feed
| Abbrev | A2AR + |
| Created | 19 September 2007 + |
| CurationStatus | uncurated + |
| DefiningCitation | Entrez Gene + |
| Definition | Alpha adrenergic receptor that is found in … Alpha adrenergic receptor that is found in platelets and has a low affinity for prazosin. Alpha-2-adrenergic receptors include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mice revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2A subtype inhibited transmitter release at high stimulation frequencies. (Adapted from Entrez Gene). n frequencies. (Adapted from Entrez Gene). |
| Has role | Adrenoceptor receptor +, Neurotransmitter Receptor +, and G-protein coupled receptor + |
| Id | nifext_6235 + |
| Is part of | Catecholamine system +, Adrenergic system +, and Noradrenergic system + |
| Label | Alpha2A receptor + |
| ModifiedDate | 13 July 2010 + |
| PMID | 7938162 + |
| RelatedTo | Epinephrine +, and Norepinephrine + |
| SuperCategory | Protein + |
| Synonym | alpha2A; alpha 2A; A2A; Alpha-2 adrenergic receptor subtype C10; Alpha-2A adrenoceptor; Alpha-2A adrenoreceptor; Alpha-2AAR; Alpha-2A adrenergic receptor +, α2A adrenoreceptor +, and ADRA2A + |



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