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Alpha2C receptor

Name: Alpha2C receptor
Description: The alpha-2C adrenergic receptor (α2C adrenoreceptor), also known as ADRA2C, is an alpha-2 adrenergic receptor, and also denotes the human gene encoding it. Alpha-2-adrenergic receptors include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. (Adapted from Entrez Gene).
Synonym(s): alpha2C; alpha 2C; A2C; Alpha-2 adrenergic receptor subtype C4; Alpha-2C adrenoceptor; Alpha-2C adrenoreceptor; Alpha-2C adrenergic receptor, α2C adrenoreceptor, ADRA2C;
Abbreviation: A2CR
Is part of: Catecholamine system, Adrenergic system, Noradrenergic system
Has role: Adrenoceptor receptor, Neurotransmitter Receptor, G-protein coupled recpetor
Super-category: Protein
URL: Entrez Gene
*Id: nifext_7113
PMID: PMID 7938162
Related to: Epinephrine, Norepinephrine
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Categories related to Alpha2C receptor

Bethanidine, Brimonidine, Fenoldopam, Guanadrel Sulfate, Guanethidine, Norepinephrine, Yohimbine


Subcategories

This category has the following 3 subcategories, out of 3 total.

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*Note: Neurolex imports many terms and their ids from existing community ontologies, e.g., the Gene Ontology. Neurolex, however, is a dynamic site and any content beyond the identifier should not be presumed to reflect the content or views of the source ontology. Users should consult with the authoritative source for each ontology for current information.

Facts about Alpha2C receptorRDF feed
AbbrevA2CR  +
Created19 September 2007  +
CurationStatusuncurated  +
DefiningCitationEntrez Gene  +
DefinitionThe alpha-2C adrenergic receptor (α2C adre The alpha-2C adrenergic receptor (α2C adrenoreceptor), also known as ADRA2C, is an alpha-2 adrenergic receptor, and also denotes the human gene encoding it. Alpha-2-adrenergic receptors include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. (Adapted from Entrez Gene). erve activity. (Adapted from Entrez Gene).
Has roleAdrenoceptor receptor  +, Neurotransmitter Receptor  +, and G-protein coupled recpetor  +
Idnifext_7113  +
Is part ofCatecholamine system  +, Adrenergic system  +, and Noradrenergic system  +
LabelAlpha2C receptor  +
ModifiedDate22 May 2010  +
PMID7938162  +
RelatedToEpinephrine  +, and Norepinephrine  +
SuperCategoryProtein  +
Synonymalpha2C; alpha 2C; A2C; Alpha-2 adrenergic receptor subtype C4; Alpha-2C adrenoceptor; Alpha-2C adrenoreceptor; Alpha-2C adrenergic receptor  +, α2C adrenoreceptor  +, and ADRA2C;  +