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Alpha 3 Acetylcholine Receptor

Name: Alpha 3 Acetylcholine Receptor
Description: Neuronal acetylcholine receptor subunit alpha-3 is encoded by the human CHRNA3 gene. This protein plays a role in ion transport. After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Neuronal AChR is composed of two different types of subunits: alpha and beta. Alpha-3 subunit can be combined to beta-2 or beta-4 to give rise to functional receptors. Interacts with RIC3; which is required for proper folding and assembly. (Adapted from NCBI and Swiss-Prot).
Synonym(s): Neuronal Acetylcholine Receptor Subunit Alpha-3, CHRNA3, NACHRA3, Cholinergic receptor, nicotinic, alpha 1
Is part of: Cholinergic system
Related to: Acetylcholine, Nicotine, Carbachol, Epibatidine, Dimethylphenylpiperazinium, Varenicline, Mecamylamine, Trimetaphan, Hexamethonium, Bupropion, Dextromethorphan, Ibogaine, 18-methoxycoronaridine
Has role: Acetylcholine Receptor, Ion Channel
Super-category: Protein
URL: NCBI, and Swiss-Prot
Id: sao99825125
Link to OWL / RDF: Download this content as OWL/RDF

Categories related to Alpha 3 Acetylcholine Receptor

Bupropion, Dextromethorphan, Epibatidine, Mecamylamine, Varenicline


PRotein Ontology ID: PRO:000005456

Updated by AY

Contributors

Admin, Ayeliset, Bandrow, Nifbot2



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Facts about Alpha 3 Acetylcholine ReceptorRDF feed
CurationStatusuncurated  +
DefiningCitationNCBI, and Swiss-Prot  +
DefinitionNeuronal acetylcholine receptor subunit al Neuronal acetylcholine receptor subunit alpha-3 is encoded by the human CHRNA3 gene. This protein plays a role in ion transport. After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Neuronal AChR is composed of two different types of subunits: alpha and beta. Alpha-3 subunit can be combined to beta-2 or beta-4 to give rise to functional receptors. Interacts with RIC3; which is required for proper folding and assembly. (Adapted from NCBI and Swiss-Prot). embly. (Adapted from NCBI and Swiss-Prot).
Has roleAcetylcholine Receptor  +, and Ion Channel  +
Idsao99825125  +
Is part ofCholinergic system  +
LabelAlpha 3 Acetylcholine Receptor  +
ModifiedDate4 June 2010  +
RelatedToAcetylcholine  +, Nicotine  +, Carbachol  +, Epibatidine  +, Dimethylphenylpiperazinium  +, Varenicline  +, Mecamylamine  +, Trimetaphan  +, Hexamethonium  +, Bupropion  +, Dextromethorphan  +, Ibogaine  +, and 18-methoxycoronaridine  +
SuperCategoryProtein  +
SynonymNeuronal Acetylcholine Receptor Subunit Alpha-3  +, CHRNA3  +, NACHRA3  +, Cholinergic receptor  +, nicotinic  +, and alpha 1  +