Alpha 3 Acetylcholine Receptor

Name:	Alpha 3 Acetylcholine Receptor
Description:	Neuronal acetylcholine receptor subunit alpha-3 is encoded by the human CHRNA3 gene. This protein plays a role in ion transport. After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Neuronal AChR is composed of two different types of subunits: alpha and beta. Alpha-3 subunit can be combined to beta-2 or beta-4 to give rise to functional receptors. Interacts with RIC3; which is required for proper folding and assembly. (Adapted from NCBI and Swiss-Prot).
Synonym(s):	Neuronal Acetylcholine Receptor Subunit Alpha-3, CHRNA3, NACHRA3, Cholinergic receptor, nicotinic, alpha 1
Is part of:	Cholinergic system
Related to:	Acetylcholine, Nicotine, Carbachol, Epibatidine, Dimethylphenylpiperazinium, Varenicline, Mecamylamine, Trimetaphan, Hexamethonium, Bupropion, Dextromethorphan, Ibogaine, 18-methoxycoronaridine
Has role:	Acetylcholine Receptor, Ion Channel
Super-category:	Protein
URL:	NCBI, and Swiss-Prot
Id:	sao99825125
Link to OWL / RDF:	Download this content as OWL/RDF

Categories related to Alpha 3 Acetylcholine Receptor

PRotein Ontology ID: PRO:000005456

Updated by AY

CurationStatus	uncurated +
DefiningCitation	NCBI, and Swiss-Prot +
Definition	Neuronal acetylcholine receptor subunit al … Neuronal acetylcholine receptor subunit alpha-3 is encoded by the human CHRNA3 gene. This protein plays a role in ion transport. After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Neuronal AChR is composed of two different types of subunits: alpha and beta. Alpha-3 subunit can be combined to beta-2 or beta-4 to give rise to functional receptors. Interacts with RIC3; which is required for proper folding and assembly. (Adapted from NCBI and Swiss-Prot). embly. (Adapted from NCBI and Swiss-Prot).
Has role	Acetylcholine Receptor +, and Ion Channel +
Id	sao99825125 +
Is part of	Cholinergic system +
Label	Alpha 3 Acetylcholine Receptor +
ModifiedDate	4 June 2010 +
RelatedTo	Acetylcholine +, Nicotine +, Carbachol +, Epibatidine +, Dimethylphenylpiperazinium +, Varenicline +, Mecamylamine +, Trimetaphan +, Hexamethonium +, Bupropion +, Dextromethorphan +, Ibogaine +, and 18-methoxycoronaridine +
SuperCategory	Protein +
Synonym	Neuronal Acetylcholine Receptor Subunit Alpha-3 +, CHRNA3 +, NACHRA3 +, Cholinergic receptor +, nicotinic +, and alpha 1 +