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Alpha 3 Acetylcholine Receptor

Name: Alpha 3 Acetylcholine Receptor
Description: Neuronal acetylcholine receptor subunit alpha-3 is encoded by the human CHRNA3 gene. This protein plays a role in ion transport. After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Neuronal AChR is composed of two different types of subunits: alpha and beta. Alpha-3 subunit can be combined to beta-2 or beta-4 to give rise to functional receptors. Interacts with RIC3; which is required for proper folding and assembly. (Adapted from NCBI and Swiss-Prot).
Synonym(s): Neuronal Acetylcholine Receptor Subunit Alpha-3, CHRNA3, NACHRA3, Cholinergic receptor, nicotinic, alpha 1
Is part of: Cholinergic system
Has role: Acetylcholine Receptor, Ion Channel
Super-category: Protein
URL: NCBI, and Swiss-Prot
*Id: sao99825125
Related to: Acetylcholine, Nicotine, Carbachol, Epibatidine, Dimethylphenylpiperazinium, Varenicline, Mecamylamine, Trimetaphan, Hexamethonium, Bupropion, Dextromethorphan, Ibogaine, 18-methoxycoronaridine
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Categories related to Alpha 3 Acetylcholine Receptor

Bupropion, Dextromethorphan, Epibatidine, Mecamylamine, Varenicline


PRotein Ontology ID: PRO:000005456

Updated by AY

Contributors

Admin, Ayeliset, Bandrow, Nifbot2



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*Note: Neurolex imports many terms and their ids from existing community ontologies, e.g., the Gene Ontology. Neurolex, however, is a dynamic site and any content beyond the identifier should not be presumed to reflect the content or views of the source ontology. Users should consult with the authoritative source for each ontology for current information.

Facts about Alpha 3 Acetylcholine ReceptorRDF feed
CurationStatusuncurated  +
DefiningCitationNCBI, and Swiss-Prot  +
DefinitionNeuronal acetylcholine receptor subunit al Neuronal acetylcholine receptor subunit alpha-3 is encoded by the human CHRNA3 gene. This protein plays a role in ion transport. After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Neuronal AChR is composed of two different types of subunits: alpha and beta. Alpha-3 subunit can be combined to beta-2 or beta-4 to give rise to functional receptors. Interacts with RIC3; which is required for proper folding and assembly. (Adapted from NCBI and Swiss-Prot). embly. (Adapted from NCBI and Swiss-Prot).
Has roleAcetylcholine Receptor  +, and Ion Channel  +
Idsao99825125  +
Is part ofCholinergic system  +
LabelAlpha 3 Acetylcholine Receptor  +
ModifiedDate4 June 2010  +
RelatedToAcetylcholine  +, Nicotine  +, Carbachol  +, Epibatidine  +, Dimethylphenylpiperazinium  +, Varenicline  +, Mecamylamine  +, Trimetaphan  +, Hexamethonium  +, Bupropion  +, Dextromethorphan  +, Ibogaine  +, and 18-methoxycoronaridine  +
SuperCategoryProtein  +
SynonymNeuronal Acetylcholine Receptor Subunit Alpha-3  +, CHRNA3  +, NACHRA3  +, Cholinergic receptor  +, nicotinic  +, and alpha 1  +