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Aromatic L-Amino Acid Decarboxylase

Name: Aromatic L-Amino Acid Decarboxylase
Description: A protein that is a translation product of the DDC gene or a 1:1 ortholog thereof. It is a synthetic enzyme that is involved in the second step of the catecholamine synthesis, in which it converts L-DOPA to dopamine via the removal of the carboxyl group from the alpha-carbon on the side chain, with the subsequent liberation of free carbon dioxide. This process also involves the co-factor Pyridoxal phosphate. AADC acts on a variety of aromatic amino acids besides DOPA. (Adapted from "Principles of Neuropsychopharmacology" and PRotein Ontology).
Synonym(s): DOPA decarboxylase; DDC; Dopa decarboxylase; Dopa-decarboxylase; DOPA-decarboxylase; Aromatic L-amino acid decarboxylase; EC 4.1.1.28;
Abbreviation: AADC
Is part of: Catecholamine system, Dopaminergic system
Has role: Synthetic Enzyme
Super-category: Protein
URL: PRotein Ontology; "Principles of Neuropsychopharmacology" Feldman, Meyer, and Quenzer
*Id: PRO:000006342
Related to: Dopamine, L Dopa, Dopaminergic system, Pyridoxal Phosphate
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*Neurolex imports many terms from existing community ontologies, e.g., the Gene Ontology. We try to re-use the original identifier when possible and often import content from the original ontology. However, Neurolex is a dynamic site and any content beyond the identifier should not be presumed to reflect the content or views of the source ontology. Users should consult with the authoritative source for each ontology for current information.

Facts about Aromatic L-Amino Acid DecarboxylaseRDF feed
AbbrevAADC  +
CurationStatusuncurated  +
DefiningCitationPRotein Ontology; "Principles of Neuropsychopharmacology" Feldman, Meyer, and Quenzer  +
DefinitionA protein that is a translation product of A protein that is a translation product of the DDC gene or a 1:1 ortholog thereof. It is a synthetic enzyme that is involved in the second step of the catecholamine synthesis, in which it converts L-DOPA to dopamine via the removal of the carboxyl group from the alpha-carbon on the side chain, with the subsequent liberation of free carbon dioxide. This process also involves the co-factor Pyridoxal phosphate. AADC acts on a variety of aromatic amino acids besides DOPA. (Adapted from "Principles of Neuropsychopharmacology" and PRotein Ontology). psychopharmacology" and PRotein Ontology).
Has roleSynthetic Enzyme  +
IdPRO:000006342  +
Is part ofCatecholamine system  +, and Dopaminergic system  +
LabelAromatic L-Amino Acid Decarboxylase  +
ModifiedDate1 May 2010  +
RelatedToDopamine  +, L Dopa  +, Dopaminergic system  +, and Pyridoxal Phosphate  +
SuperCategoryProtein  +
SynonymDOPA decarboxylase; DDC; Dopa decarboxylase; Dopa-decarboxylase; DOPA-decarboxylase; Aromatic L-amino acid decarboxylase; EC 4.1.1.28;  +