EditFrom NeuroLex
Azithromycin
| Name: | Azithromycin |
| Description: | A semi-synthetic macrolide antibiotic structurally related to erythromycin. It has been used in the treatment of Mycobacterium avium intracellulare infections, toxoplasmosis, and cryptosporidiosis. (PubChem) Pharmacology: Azithromycin, a semisynthetic antibiotic belonging to the macrolide subgroup of azalides, is used to treat STDs due to chlamydia and gonorrhea, community-acquired pneumonia, pelvic inflammatory disease, pediatric otitis media and pharyngitis, and Mycobacterium avium complex (MAC) in patients with advanced HIV disease. Similar in structure to erythromycin. azithromycin reaches higher intracellular concentrations than erythromycin, increasing its efficacy and duration of action. Mechanism of action: Azithromycin binds to the 50S subunit of the 70S bacterial ribosomes, and therefore inhibits RNA-dependent protein synthesis in bacterial cells. Drug type: Approved. Small Molecule. Drug category: Anti-Bacterial Agents. Macrolides. Other Macrolides |
| Synonym(s): | Aritromicina (Spanish), Azithramycine, Azithromycin Dihydrate, Azithromycine (French), Azithromycinum (Latin), Azenil, Azibiot, Azifine, Azitromax, Aziwok, Aztrin, Hemomycin, Misultina, Mixoterin, Setron, Sumamed, Tobil, Tromix, Vinzam, Zeto, Zifin, Zithrax, Zithromax, Zitrim, Zitrocin, Zitromax, Zitrotek, Zmax |
| Related to: | 23S rRNA, 50S ribosomal protein L22, 50S ribosomal protein L4 |
| Has role: | Drug |
| Super-category: | Molecule |
| URL: | http://www.drugbank.ca/drugs/DB00207 |
| Id: | CHEBI_2955 |
| Link to OWL / RDF: | Download this content as OWL/RDF |
Facts about AzithromycinRDF feed
| Comment | taken from DrugBank |
| CurationStatus | uncurated + |
| Curator | Ab + |
| DefiningCitation | http://www.drugbank.ca/drugs/DB00207 + |
| Definition | A semi-synthetic macrolide antibiotic stru … A semi-synthetic macrolide antibiotic structurally related to erythromycin. It has been used in the treatment of Mycobacterium avium intracellulare infections, toxoplasmosis, and cryptosporidiosis. (PubChem) Pharmacology: Azithromycin, a semisynthetic antibiotic belonging to the macrolide subgroup of azalides, is used to treat STDs due to chlamydia and gonorrhea, community-acquired pneumonia, pelvic inflammatory disease, pediatric otitis media and pharyngitis, and Mycobacterium avium complex (MAC) in patients with advanced HIV disease. Similar in structure to erythromycin. azithromycin reaches higher intracellular concentrations than erythromycin, increasing its efficacy and duration of action. Mechanism of action: Azithromycin binds to the 50S subunit of the 70S bacterial ribosomes, and therefore inhibits RNA-dependent protein synthesis in bacterial cells. Drug type: Approved. Small Molecule. Drug category: Anti-Bacterial Agents. Macrolides. Other Macrolides erial Agents. Macrolides. Other Macrolides |
| Has role | Drug + |
| Id | CHEBI_2955 + |
| Label | Azithromycin + |
| ModifiedDate | 2 December 2010 + |
| RelatedTo | 23S rRNA +, 50S ribosomal protein L22 +, and 50S ribosomal protein L4 + |
| SuperCategory | Molecule + |
| Synonym | Aritromicina (Spanish) +, Azithramycine +, Azithromycin Dihydrate +, Azithromycine (French) +, Azithromycinum (Latin) +, Azenil +, Azibiot +, Azifine +, Azitromax +, Aziwok +, Aztrin +, Hemomycin +, Misultina +, Mixoterin +, Setron +, Sumamed +, Tobil +, Tromix +, Vinzam +, Zeto +, Zifin +, Zithrax +, Zithromax +, Zitrim +, Zitrocin +, Zitromax +, Zitrotek +, and Zmax + |