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Azithromycin

Name: Azithromycin
Description: A semi-synthetic macrolide antibiotic structurally related to erythromycin. It has been used in the treatment of Mycobacterium avium intracellulare infections, toxoplasmosis, and cryptosporidiosis. (PubChem) Pharmacology: Azithromycin, a semisynthetic antibiotic belonging to the macrolide subgroup of azalides, is used to treat STDs due to chlamydia and gonorrhea, community-acquired pneumonia, pelvic inflammatory disease, pediatric otitis media and pharyngitis, and Mycobacterium avium complex (MAC) in patients with advanced HIV disease. Similar in structure to erythromycin. azithromycin reaches higher intracellular concentrations than erythromycin, increasing its efficacy and duration of action. Mechanism of action: Azithromycin binds to the 50S subunit of the 70S bacterial ribosomes, and therefore inhibits RNA-dependent protein synthesis in bacterial cells. Drug type: Approved. Small Molecule. Drug category: Anti-Bacterial Agents. Macrolides. Other Macrolides
Synonym(s): Aritromicina (Spanish), Azithramycine, Azithromycin Dihydrate, Azithromycine (French), Azithromycinum (Latin), Azenil, Azibiot, Azifine, Azitromax, Aziwok, Aztrin, Hemomycin, Misultina, Mixoterin, Setron, Sumamed, Tobil, Tromix, Vinzam, Zeto, Zifin, Zithrax, Zithromax, Zitrim, Zitrocin, Zitromax, Zitrotek, Zmax
Has role: Drug
Super-category: Molecular entity
URL: http://www.drugbank.ca/drugs/DB00207
*Id: CHEBI:2955
Related to: 23S rRNA, 50S ribosomal protein L22, 50S ribosomal protein L4
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Facts about AzithromycinRDF feed
Commenttaken from DrugBank
CurationStatusuncurated  +
CuratorAb  +
DefiningCitationhttp://www.drugbank.ca/drugs/DB00207  +
DefinitionA semi-synthetic macrolide antibiotic stru A semi-synthetic macrolide antibiotic structurally related to erythromycin. It has been used in the treatment of Mycobacterium avium intracellulare infections, toxoplasmosis, and cryptosporidiosis. (PubChem) Pharmacology: Azithromycin, a semisynthetic antibiotic belonging to the macrolide subgroup of azalides, is used to treat STDs due to chlamydia and gonorrhea, community-acquired pneumonia, pelvic inflammatory disease, pediatric otitis media and pharyngitis, and Mycobacterium avium complex (MAC) in patients with advanced HIV disease. Similar in structure to erythromycin. azithromycin reaches higher intracellular concentrations than erythromycin, increasing its efficacy and duration of action. Mechanism of action: Azithromycin binds to the 50S subunit of the 70S bacterial ribosomes, and therefore inhibits RNA-dependent protein synthesis in bacterial cells. Drug type: Approved. Small Molecule. Drug category: Anti-Bacterial Agents. Macrolides. Other Macrolides erial Agents. Macrolides. Other Macrolides
Has roleDrug  +
IdCHEBI:2955  +
LabelAzithromycin  +
ModifiedDate12 August 2014  +
RelatedTo23S rRNA  +, 50S ribosomal protein L22  +, and 50S ribosomal protein L4  +
SuperCategoryMolecular entity  +
SynonymAritromicina (Spanish)  +, Azithramycine  +, Azithromycin Dihydrate  +, Azithromycine (French)  +, Azithromycinum (Latin)  +, Azenil  +, Azibiot  +, Azifine  +, Azitromax  +, Aziwok  +, Aztrin  +, Hemomycin  +, Misultina  +, Mixoterin  +, Setron  +, Sumamed  +, Tobil  +, Tromix  +, Vinzam  +, Zeto  +, Zifin  +, Zithrax  +, Zithromax  +, Zitrim  +, Zitrocin  +, Zitromax  +, Zitrotek  +, and Zmax  +