EditFrom NeuroLex
BXH
| Name: | BXH |
| Super-category: | Recombinant inbred mouse strain |
| Id: | birnlex_130 |
| Link to OWL / RDF: | Download this content as OWL/RDF |
- Externally Sourced Definition: Inbr 30+. Set of 13 recombinant inbred strains developed by B.A.Taylor from C57BL/6J x C3H/HeJ. Maint. by Ty. Strain BXH2 develop myeloid leukemia as a result of the expression of an ecotropic murine leukaemia virus that acts as an insertional mutagen altering the expression of cellular proto-oncogenes. This is not passed through the germ line, but is passed from one generation to the next by horizontal transmission (Bedigian et al, 1993). A homeobox locus Meis1 is the site of viral integration in 15% of tumours (Moskow et al, 1995).
- Abbreviation Source: MGI
Facts about BXHRDF feed
| AbbrevSource | MGI + |
| Created | 16 August 2007 + |
| CurationStatus | pending_final_vetting + |
| ExternallySourcedDefinition | Inbr 30+. Set of 13 recombinant inbred str … Inbr 30+. Set of 13 recombinant inbred strains developed by B.A.Taylor from C57BL/6J x C3H/HeJ. Maint. by Ty. Strain BXH2 develop myeloid leukemia as a result of the expression of an ecotropic murine leukaemia virus that acts as an insertional mutagen altering the expression of cellular proto-oncogenes. This is not passed through the germ line, but is passed from one generation to the next by horizontal transmission (Bedigian et al, 1993). A homeobox locus Meis1 is the site of viral integration in 15% of tumours (Moskow et al, 1995). on in 15% of tumours (Moskow et al, 1995). |
| Id | birnlex_130 + |
| Label | BXH + |
| ModifiedDate | 29 May 2009 + |
| SuperCategory | Recombinant inbred mouse strain + |