arrow

From NeuroLex

Jump to: navigation, search



BXH


  • Externally Sourced Definition: Inbr 30+. Set of 13 recombinant inbred strains developed by B.A.Taylor from C57BL/6J x C3H/HeJ. Maint. by Ty. Strain BXH2 develop myeloid leukemia as a result of the expression of an ecotropic murine leukaemia virus that acts as an insertional mutagen altering the expression of cellular proto-oncogenes. This is not passed through the germ line, but is passed from one generation to the next by horizontal transmission (Bedigian et al, 1993). A homeobox locus Meis1 is the site of viral integration in 15% of tumours (Moskow et al, 1995).
  • Abbreviation Source: MGI

Contributors

Admin, Nifbot2



bookmark

*Note: Neurolex imports many terms and their ids from existing community ontologies, e.g., the Gene Ontology. Neurolex, however, is a dynamic site and any content beyond the identifier should not be presumed to reflect the content or views of the source ontology. Users should consult with the authoritative source for each ontology for current information.

Facts about BXHRDF feed
AbbrevSourceMGI  +
Created16 August 2007  +
CurationStatuspending_final_vetting  +
ExternallySourcedDefinitionInbr 30+. Set of 13 recombinant inbred str Inbr 30+. Set of 13 recombinant inbred strains developed by B.A.Taylor from C57BL/6J x C3H/HeJ. Maint. by Ty. Strain BXH2 develop myeloid leukemia as a result of the expression of an ecotropic murine leukaemia virus that acts as an insertional mutagen altering the expression of cellular proto-oncogenes. This is not passed through the germ line, but is passed from one generation to the next by horizontal transmission (Bedigian et al, 1993). A homeobox locus Meis1 is the site of viral integration in 15% of tumours (Moskow et al, 1995). on in 15% of tumours (Moskow et al, 1995).
Idbirnlex_130  +
LabelBXH  +
ModifiedDate29 May 2009  +
SuperCategoryRecombinant inbred mouse strain  +