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BXH


  • Externally Sourced Definition: Inbr 30+. Set of 13 recombinant inbred strains developed by B.A.Taylor from C57BL/6J x C3H/HeJ. Maint. by Ty. Strain BXH2 develop myeloid leukemia as a result of the expression of an ecotropic murine leukaemia virus that acts as an insertional mutagen altering the expression of cellular proto-oncogenes. This is not passed through the germ line, but is passed from one generation to the next by horizontal transmission (Bedigian et al, 1993). A homeobox locus Meis1 is the site of viral integration in 15% of tumours (Moskow et al, 1995).
  • Abbreviation Source: MGI

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Facts about BXHRDF feed
AbbrevSourceMGI  +
Created16 August 2007  +
CurationStatuspending_final_vetting  +
ExternallySourcedDefinitionInbr 30+. Set of 13 recombinant inbred str Inbr 30+. Set of 13 recombinant inbred strains developed by B.A.Taylor from C57BL/6J x C3H/HeJ. Maint. by Ty. Strain BXH2 develop myeloid leukemia as a result of the expression of an ecotropic murine leukaemia virus that acts as an insertional mutagen altering the expression of cellular proto-oncogenes. This is not passed through the germ line, but is passed from one generation to the next by horizontal transmission (Bedigian et al, 1993). A homeobox locus Meis1 is the site of viral integration in 15% of tumours (Moskow et al, 1995). on in 15% of tumours (Moskow et al, 1995).
Idbirnlex_130  +
LabelBXH  +
ModifiedDate29 May 2009  +
SuperCategoryRecombinant inbred mouse strain  +