EditFrom NeuroLex
Benzocaine
| Name: | Benzocaine |
| Description: | A surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. (PubChem) Pharmacology: Benzocaine is a local anesthetic commonly used as a topical pain reliever. It is the active ingredient in many over-the-counter analgesic ointments. It is also indicated for general use as a lubricant and topical anesthetic on intratracheal catheters and pharyngeal and nasal airways to obtund the pharyngeal and tracheal reflexes; on nasogastric and endoscopic tubes; urinary catheters; laryngoscopes; proctoscopes; sigmoidoscopes and vaginal specula. Mechanism of action: Benzocaine binds to sodium channel and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions. Depolarization of the neuronal membrane is inhibited thereby blocking the initiation and conduction of nerve impulses. Drug type: Approved. Small Molecule. Drug category: Anesthetics. Anesthetics, Local. Antipruritics. Local Anesthetics |
| Synonym(s): | Ethyl Aminobenzoate, Ethyl P-Aminobenzoate, Ethyl P-Aminophenylcarboxylate, Ethylester Kyseliny P-Aminobenzoove, P-Aminobenzoic Acid, Ethyl Ester, P-Carbethoxyaniline, P-Ethoxycarboxylic Aniline, Aethoform, Amben Ethyl Ester, Americaine, Anaesthan-Syngala, Anaesthesin, Anaesthin, Anestezin, Anesthesin, Anesthesine, Anesthone, Baby Anbesol, Dermoplast, Ethoform, Hurricaine, Identhesin, Keloform, Norcain, Norcaine, Ora-Jel, Orthesin, Parathesin, Parathesine, Solu H, Topcaine |
| Related to: | Sodium channel protein type 10 subunit alpha |
| Has role: | Drug |
| Super-category: | Molecule |
| URL: | http://www.drugbank.ca/drugs/DB01086 |
| Id: | DB01086 |
| Link to OWL / RDF: | Download this content as OWL/RDF |
Facts about BenzocaineRDF feed
| Comment | taken from DrugBank |
| Curator | Ab + |
| DefiningCitation | http://www.drugbank.ca/drugs/DB01086 + |
| Definition | A surface anesthetic that acts by preventi … A surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. (PubChem) Pharmacology: Benzocaine is a local anesthetic commonly used as a topical pain reliever. It is the active ingredient in many over-the-counter analgesic ointments. It is also indicated for general use as a lubricant and topical anesthetic on intratracheal catheters and pharyngeal and nasal airways to obtund the pharyngeal and tracheal reflexes; on nasogastric and endoscopic tubes; urinary catheters; laryngoscopes; proctoscopes; sigmoidoscopes and vaginal specula. Mechanism of action: Benzocaine binds to sodium channel and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions. Depolarization of the neuronal membrane is inhibited thereby blocking the initiation and conduction of nerve impulses. Drug type: Approved. Small Molecule. Drug category: Anesthetics. Anesthetics, Local. Antipruritics. Local Anesthetics s, Local. Antipruritics. Local Anesthetics |
| Has role | Drug + |
| Id | DB01086 + |
| Label | Benzocaine + |
| ModifiedDate | 4 February 2010 + |
| RelatedTo | Sodium channel protein type 10 subunit alpha + |
| SuperCategory | Molecule + |
| Synonym | Ethyl Aminobenzoate +, Ethyl P-Aminobenzoate +, Ethyl P-Aminophenylcarboxylate +, Ethylester Kyseliny P-Aminobenzoove +, P-Aminobenzoic Acid +, Ethyl Ester +, P-Carbethoxyaniline +, P-Ethoxycarboxylic Aniline +, Aethoform +, Amben Ethyl Ester +, Americaine +, Anaesthan-Syngala +, Anaesthesin +, Anaesthin +, Anestezin +, Anesthesin +, Anesthesine +, Anesthone +, Baby Anbesol +, Dermoplast +, Ethoform +, Hurricaine +, Identhesin +, Keloform +, Norcain +, Norcaine +, Ora-Jel +, Orthesin +, Parathesin +, Parathesine +, Solu H +, and Topcaine + |