arrow

From NeuroLex

Jump to: navigation, search



Benzocaine

Name: Benzocaine
Description: A surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. (PubChem) Pharmacology: Benzocaine is a local anesthetic commonly used as a topical pain reliever. It is the active ingredient in many over-the-counter analgesic ointments. It is also indicated for general use as a lubricant and topical anesthetic on intratracheal catheters and pharyngeal and nasal airways to obtund the pharyngeal and tracheal reflexes; on nasogastric and endoscopic tubes; urinary catheters; laryngoscopes; proctoscopes; sigmoidoscopes and vaginal specula. Mechanism of action: Benzocaine binds to sodium channel and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions. Depolarization of the neuronal membrane is inhibited thereby blocking the initiation and conduction of nerve impulses. Drug type: Approved. Small Molecule. Drug category: Anesthetics. Anesthetics, Local. Antipruritics. Local Anesthetics
Synonym(s): Ethyl Aminobenzoate, Ethyl P-Aminobenzoate, Ethyl P-Aminophenylcarboxylate, Ethylester Kyseliny P-Aminobenzoove, P-Aminobenzoic Acid, Ethyl Ester, P-Carbethoxyaniline, P-Ethoxycarboxylic Aniline, Aethoform, Amben Ethyl Ester, Americaine, Anaesthan-Syngala, Anaesthesin, Anaesthin, Anestezin, Anesthesin, Anesthesine, Anesthone, Baby Anbesol, Dermoplast, Ethoform, Hurricaine, Identhesin, Keloform, Norcain, Norcaine, Ora-Jel, Orthesin, Parathesin, Parathesine, Solu H, Topcaine
Related to: Sodium channel protein type 10 subunit alpha
Has role: Drug
Super-category: Molecular entity
URL: http://www.drugbank.ca/drugs/DB01086
Id: DB01086
Link to OWL / RDF: Download this content as OWL/RDF


Contributors

Ccdbuser, Nifbot2



bookmark
Facts about BenzocaineRDF feed
Commenttaken from DrugBank
CuratorAb  +
DefiningCitationhttp://www.drugbank.ca/drugs/DB01086  +
DefinitionA surface anesthetic that acts by preventi A surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. (PubChem) Pharmacology: Benzocaine is a local anesthetic commonly used as a topical pain reliever. It is the active ingredient in many over-the-counter analgesic ointments. It is also indicated for general use as a lubricant and topical anesthetic on intratracheal catheters and pharyngeal and nasal airways to obtund the pharyngeal and tracheal reflexes; on nasogastric and endoscopic tubes; urinary catheters; laryngoscopes; proctoscopes; sigmoidoscopes and vaginal specula. Mechanism of action: Benzocaine binds to sodium channel and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions. Depolarization of the neuronal membrane is inhibited thereby blocking the initiation and conduction of nerve impulses. Drug type: Approved. Small Molecule. Drug category: Anesthetics. Anesthetics, Local. Antipruritics. Local Anesthetics s, Local. Antipruritics. Local Anesthetics
Has roleDrug  +
IdDB01086  +
LabelBenzocaine  +
ModifiedDate14 April 2014  +
RelatedToSodium channel protein type 10 subunit alpha  +
SuperCategoryMolecular entity  +
SynonymEthyl Aminobenzoate  +, Ethyl P-Aminobenzoate  +, Ethyl P-Aminophenylcarboxylate  +, Ethylester Kyseliny P-Aminobenzoove  +, P-Aminobenzoic Acid  +, Ethyl Ester  +, P-Carbethoxyaniline  +, P-Ethoxycarboxylic Aniline  +, Aethoform  +, Amben Ethyl Ester  +, Americaine  +, Anaesthan-Syngala  +, Anaesthesin  +, Anaesthin  +, Anestezin  +, Anesthesin  +, Anesthesine  +, Anesthone  +, Baby Anbesol  +, Dermoplast  +, Ethoform  +, Hurricaine  +, Identhesin  +, Keloform  +, Norcain  +, Norcaine  +, Ora-Jel  +, Orthesin  +, Parathesin  +, Parathesine  +, Solu H  +, and Topcaine  +