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Beta3 receptor

Name: Beta3 receptor
Description: Beta adrenergic receptor found in brown adipose tissue, which stimulates lipolysis and thermogenesis. This receptor class has a low affinity for beta1 and beta2 receptors, but a high affinity for BRL 37344 and its derivatives. It is located mainly in adipose tissue and is involved in the regulation of lipolysis and thermogenesis. Some β3 agonists have demonstrated antistress effects in animal studies, suggesting it also has a role in the CNS. Beta3-Receptors are found in the gallbladder, urinary bladder, and in brain adipose tissue. Their role in gallbladder physiology is unknown, but they are thought to play a role in lipolysis and thermogenesis in brown fat. In the urinary bladder it is thought to cause relaxation of the bladder and prevention of urination.
Synonym(s): beta3; beta 3; b;3Beta-3 adrenoceptor; Beta-3 adrenoreceptor; Beta-3 adrenergic receptor; β3 adrenoreceptor; ADRB3;
Abbreviation: B3R
Is part of: Catecholamine system, Adrenergic system, Noradrenergic system
Has role: Adrenoceptor receptor
Super-category: Protein
URL: PMID: 16457637
Id: nifext_6793
PMID: PMID 6325935,
Related to: Epinephrine, Norepinephrine
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Categories related to Beta3 receptor

Norepinephrine, Pindolol, Propranolol


Contributors

Admin, Ayeliset, Bandrow, Nifbot2

Subcategories

This category has the following 3 subcategories, out of 3 total.

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Facts about Beta3 receptorRDF feed
AbbrevB3R  +
Created19 September 2007  +
CurationStatusuncurated  +
DefiningCitationPMID: 16457637  +
DefinitionBeta adrenergic receptor found in brown ad Beta adrenergic receptor found in brown adipose tissue, which stimulates lipolysis and thermogenesis. This receptor class has a low affinity for beta1 and beta2 receptors, but a high affinity for BRL 37344 and its derivatives. It is located mainly in adipose tissue and is involved in the regulation of lipolysis and thermogenesis. Some β3 agonists have demonstrated antistress effects in animal studies, suggesting it also has a role in the CNS. Beta3-Receptors are found in the gallbladder, urinary bladder, and in brain adipose tissue. Their role in gallbladder physiology is unknown, but they are thought to play a role in lipolysis and thermogenesis in brown fat. In the urinary bladder it is thought to cause relaxation of the bladder and prevention of urination. f the bladder and prevention of urination.
Has roleAdrenoceptor receptor  +
Idnifext_6793  +
Is part ofCatecholamine system  +, Adrenergic system  +, and Noradrenergic system  +
LabelBeta3 receptor  +
ModifiedDate22 May 2010  +
PMID6325935,  +
RelatedToEpinephrine  +, and Norepinephrine  +
SuperCategoryProtein  +
Synonymbeta3; beta 3; b;3Beta-3 adrenoceptor; Beta-3 adrenoreceptor; Beta-3 adrenergic receptor; β3 adrenoreceptor; ADRB3;  +