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Cajal Body

Name: Cajal Body
Description: A class of nuclear body, first seen after silver staining by Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA.
Synonym(s): Coiled body, Gems
Id: GO:0015030
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Memartone, Mimam



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CommentThis term maps to GO:0015030
CurationStatusuncurated  +
DefinitionA class of nuclear body, first seen after A class of nuclear body, first seen after silver staining by Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA. ed in transcription and processing of RNA.
IdGO:0015030  +
LabelCajal Body  +
ModifiedDate26 July 2013  +
SynonymCoiled body  +, and Gems  +