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Climbing fiber

Name: Climbing fiber
Description: Axon of inferior olive neuron that projects to the cerebellar cortex, largely via the inferior cerebellar peduncle. They range in diameter from 1-3 um and are myelinated until they enter the granule cell layer. They give off collaterals to the deep cerebellar nuclei. They synapse extensively with the dendrites of Purkinje cells in the molecular layer, where each fiber branches repeatedly to "climb" along the Purkinje cell dendritic tree. Each Purkinje cell is innervated by only a single climbing fiber.
Synonym(s): Climbing fibre
Super-category: Axon
Id: nlx_subcell_20090203
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Ayslinn, Memartone, Nifbot2, Slarson



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CurationStatusuncurated  +
DefinitionAxon of inferior olive neuron that project Axon of inferior olive neuron that projects to the cerebellar cortex, largely via the inferior cerebellar peduncle. They range in diameter from 1-3 um and are myelinated until they enter the granule cell layer. They give off collaterals to the deep cerebellar nuclei. They synapse extensively with the dendrites of Purkinje cells in the molecular layer, where each fiber branches repeatedly to "climb" along the Purkinje cell dendritic tree. Each Purkinje cell is innervated by only a single climbing fiber. nnervated by only a single climbing fiber.
Idnlx_subcell_20090203  +
LabelClimbing fiber  +
LocationOfAxonArborizationMolecular layer of cerebellar cortex  +
ModifiedDate28 July 2010  +
SuperCategoryAxon  +
SynonymClimbing fibre  +