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Cochlea inner hair cell
| Name: | Cochlea inner hair cell |
| Description: | A pear-shaped epithelial cell that is medially placed re: the inner pillar and forms a single row within the organ of Corti. Resting potential is modulated by perturbations in stereocilia located at the apical pole of the cell. In contrast to outer hair cells, the inner hair cells are fewer in number, have fewer stereocilia, and are less differentiated. They do, however, receive ~95% of the auditory-nerve dendrites. Although a single auditory nerve fiber innervates several outer hair cells, each inner hair cell receives several more heavily myelinated, auditory-nerve dendrites. Neurotransmitter release activates the auditory nerve, which leads to the cochlear nucleus within the central auditory pathway.(MSH)[1] |
| Synonym(s): | Cochlear Inner Hair Cell, Inner Hair Cell |
| Has role: | Principal neuron role |
| Abbreviation: | IHC |
| Super-category: | Neuron |
| Id: | sao429277527 |
| Organism: | Mammal |
| Link to OWL / RDF: | Download this content as OWL/RDF |
Soma Specific Properties
| Cell Soma Shape: | Pear-shaped |
| Cell Soma Size: | Small soma |
| Soma Location: | Spiral organ of Corti |
Dendrite Specific Properties
| Spine density on dendrites: | Smooth |
Axon Specific Properties
| Origin of axon: | no axon |
Intrinsic Properties
| Neurotransmitter released: | Glutamate[2] |
| Neurotransmitter receptors: | AMPA-type glutamate-gated cationic channel[3] |
| Molecular constituents: | otoferlin[4] |
References
- ↑ Müller U & Spoendlin H (1985) Anatomy of cochlear innervation. Am J Otolaryngol 6: 453-67 PubMed
- ↑ Fuchs PA et al. (2003) The afferent synapse of cochlear hair cells. Curr Opin Neurobiol 13: 452-8 PubMed
- ↑ Safieddine S et al. (2012) The auditory hair cell ribbon synapse: from assembly to function. Annu Rev Neurosci 35: 509-28 PubMed
- ↑ Pangršič T et al. (2012) Otoferlin: a multi-C2 domain protein essential for hearing. Trends Neurosci 35: 671-80 PubMed
Category:Sensory reception role
Notes
This page uses this default form:Petilla_neuron
Contributors
Ayslinn, Bandrow, Ccdbuser, Cheatham, Gvousden, Jcachat, Mcheatham, Memartone, Pdallos, Slarson
Facts about Cochlea inner hair cellRDF feed
| Abbrev | IHC + |
| CellSomaShape | Category:Pear-shaped + |
| CellSomaSize | Small soma + |
| CurationStatus | uncurated + |
| Definition | A pear-shaped epithelial cell that is medi … A pear-shaped epithelial cell that is medially placed re: the inner pillar and forms a single row within the organ of Corti. Resting potential is modulated by perturbations in stereocilia located at the apical pole of the cell. In contrast to outer hair cells, the inner hair cells are fewer in number, have fewer stereocilia, and are less differentiated. They do, however, receive ~95% of the auditory-nerve dendrites. Although a single auditory nerve fiber innervates several outer hair cells, each inner hair cell receives several more heavily myelinated, auditory-nerve dendrites. Neurotransmitter release activates the auditory nerve, which leads to the cochlear nucleus within the central auditory pathway.(MSH) within the central auditory pathway.(MSH) |
| EditorialNote | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912990/figure/Fig1/ |
| Has default formThis property is a special property in this wiki. | Petilla neuron + |
| Has role | Principal neuron role +, and Sensory reception role + |
| Id | sao429277527 + |
| Label | Cochlea inner hair cell + |
| Located in | Spiral organ of Corti + |
| ModifiedDate | 23 April 2013 + |
| MolecularConstituents | Otoferlin + |
| Neurotransmitter | Glutamate + |
| NeurotransmitterReceptors | AMPA-type glutamate-gated cationic channel + |
| OriginOfAxon | no axon + |
| Page has default formThis property is a special property in this wiki. | Petilla neuron + |
| Species | Mammal + |
| SpineDensityOnDendrites | Smooth + |
| SuperCategory | Neuron + |
| Synonym | Cochlear Inner Hair Cell +, and Inner Hair Cell + |