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Cochlea inner hair cell

Name: Cochlea inner hair cell
Description: A pear-shaped epithelial cell that is medially placed re: the inner pillar and forms a single row within the organ of Corti. Resting potential is modulated by perturbations in stereocilia located at the apical pole of the cell. In contrast to outer hair cells, the inner hair cells are fewer in number, have fewer stereocilia, and are less differentiated. They do, however, receive ~95% of the auditory-nerve dendrites. Although a single auditory nerve fiber innervates several outer hair cells, each inner hair cell receives several more heavily myelinated, auditory-nerve dendrites. Neurotransmitter release activates the auditory nerve, which leads to the cochlear nucleus within the central auditory pathway.(MSH)[1]
Synonym(s): Cochlear Inner Hair Cell, Inner Hair Cell, Cochlea hair cell inner
Abbreviation: IHC
Has role: Principal neuron role
Super-category: Neuron
Id: sao429277527
Organism: Mammal
Link to OWL / RDF: Download this content as OWL/RDF

Soma Specific Properties

Cell Soma Shape: Pear-shaped
Cell Soma Size: Small soma
Soma Location: Spiral organ of Corti

Dendrite Specific Properties

Spine density on dendrites: Smooth

Axon Specific Properties

Origin of axon: no axon

Intrinsic Properties

Neurotransmitter released: Glutamate[2]
Neurotransmitter receptors: AMPA-type glutamate-gated cationic channel[3]
Molecular constituents: otoferlin, VGLUT3[4]


References

  1. Müller U & Spoendlin H (1985) Anatomy of cochlear innervation. Am J Otolaryngol 6: 453-67 PubMed
  2. Fuchs PA et al. (2003) The afferent synapse of cochlear hair cells. Curr Opin Neurobiol 13: 452-8 PubMed
  3. Safieddine S et al. (2012) The auditory hair cell ribbon synapse: from assembly to function. Annu Rev Neurosci 35: 509-28 PubMed
  4. et al. PubMed

Category:Sensory reception role

Notes

This page uses this default form:Petilla_neuron



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Facts about Cochlea inner hair cellRDF feed
AbbrevIHC  +
CellSomaShapeCategory:Pear-shaped   +
CellSomaSizeSmall soma  +
CurationStatusuncurated  +
DefinitionA pear-shaped epithelial cell that is medi A pear-shaped epithelial cell that is medially placed re: the inner pillar and forms a single row within the organ of Corti. Resting potential is modulated by perturbations in stereocilia located at the apical pole of the cell. In contrast to outer hair cells, the inner hair cells are fewer in number, have fewer stereocilia, and are less differentiated. They do, however, receive ~95% of the auditory-nerve dendrites. Although a single auditory nerve fiber innervates several outer hair cells, each inner hair cell receives several more heavily myelinated, auditory-nerve dendrites. Neurotransmitter release activates the auditory nerve, which leads to the cochlear nucleus within the central auditory pathway.(MSH) within the central auditory pathway.(MSH)
EditorialNotehttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912990/figure/Fig1/
Has default formThis property is a special property in this wiki.Petilla neuron  +
Has rolePrincipal neuron role  +, and Sensory reception role  +
Idsao429277527  +
LabelCochlea inner hair cell  +
Located inSpiral organ of Corti  +
ModifiedDate12 September 2013  +
MolecularConstituentsOtoferlin  +, and VGLUT3  +
NeurotransmitterGlutamate  +
NeurotransmitterReceptorsAMPA-type glutamate-gated cationic channel  +
OriginOfAxonno axon  +
Page has default formThis property is a special property in this wiki.Petilla neuron  +
SpeciesMammal  +
SpineDensityOnDendritesSmooth  +
SuperCategoryNeuron  +
SynonymCochlear Inner Hair Cell  +, Inner Hair Cell  +, and Cochlea hair cell inner  +