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Cochlear nucleus (dorsal) cartwheel cell

Name: Cochlear nucleus (dorsal) cartwheel cell
Description: Cartwheel cell bodies lie on the superficial side of the pyramidal (or fusiform) cell layer of the dorsal cochlear nucleus. Their spiny dendrites receive input from the axons of granule cells (parallel fibers) and their axons release GABA and glycine onto cartwheel, pyramidal and giant cell targets. Cartwheel cells share many of the features, molecular and electrophysiological, of cerebellar Purkinje neurons.[1]
Synonym(s): Cartwheel neuron
Has role: Intrinsic neuron role[2]
Super-category: Neuron
URL: 4134212
Id: nifext_76
Related to: Cerebellum Purkinje cell[3]
Organism: Mammal
Link to OWL / RDF: Download this content as OWL/RDF

Soma Specific Properties

Cell Soma Shape: Spherical[4]
Cell Soma Size: Medium soma[4]
Soma Location: Somas lie at the superficial side of the pyramidal (fusiform) cell layer of the dorsal cochlear nucleus.[1]

Dendrite Specific Properties

Dendrite location: Molecular layer of dorsal cochlear nucleus[5]
Spine density on dendrites: spiny high density[1]
Branching type: stellate[1]

Axon Specific Properties

Axon myelination: myelinated[6]
Axon projection laterality: ipsilateral[7]
Origin of axon: soma[4]
Location of local axon arborization: Pyramidal cells, giant cells, cartwheel cells[8]

Intrinsic Properties

Neurotransmitter released: Glycine, GABA[9]
Neurotransmitter receptors: mGluR1alpha
Molecular constituents: PEP19, cerebellin, GAD, GlyT2[10]


References

  1. 1.0 1.1 1.2 1.3 Brawer JR et al. (1994) Physiology and morphology of complex spiking neurons in the guinea pig dorsal cochlear nucleus. J Comp Neurol 348: 261-76 PubMed
  2. Berrebi AS et al. (1990) The Purkinje cell class may extend beyond the cerebellum. J Neurocytol 19: 643-54 PubMed
  3. Berrebi AS et al. (1987) The neuropeptide cerebellin is a marker for two similar neuronal circuits in rat brain. Proc Natl Acad Sci U S A 84: 8692-6 PubMed
  4. 4.0 4.1 4.2 Zhang S et al. (1994) Physiology and morphology of complex spiking neurons in the guinea pig dorsal cochlear nucleus. J Comp Neurol 348: 261-76 PubMed
  5. Zhang S & Oertel D (1993) Cartwheel and superficial stellate cells of the dorsal cochlear nucleus of mice: intracellular recordings in slices. J Neurophysiol 69: 1384-97 PubMed
  6. Bender KJ et al. (2012) Control of firing patterns through modulation of axon initial segment T-type calcium channels. J Physiol 590: 109-18 PubMed
  7. Zhang S et al. (1991) Distribution and targets of the cartwheel cell axon in the dorsal cochlear nucleus of the guinea pig. Anat Embryol (Berl) 183: 427-54 PubMed
  8. Berrebi AS et al. (2011) Spontaneous spiking and synaptic depression underlie noradrenergic control of feed-forward inhibition. Neuron 71: 306-18 PubMed
  9. Apostolides PF et al. (2011) Spontaneous spiking and synaptic depression underlie noradrenergic control of feed-forward inhibition. Neuron 71: 306-18 PubMed
  10. Berrebi AS et al. (2013) Rapid, activity-independent turnover of vesicular transmitter content at a mixed glycine/GABA synapse. J Neurosci 33: 4768-81 PubMed

Notes

This page uses this default form:Petilla_neuron

  • Dendrites span the molecular layer


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Facts about Cochlear nucleus (dorsal) cartwheel cellRDF feed
AxonMyelinationmyelinated  +
AxonProjectionLateralityipsilateral  +
BranchingMetricsstellate  +
CellSomaShapeCategory:Spherical   +
CellSomaSizeMedium soma  +
CellularSynapticTargetCochlear (dorsal) nucleus pyramidal neuron  +
Created5 September 2007  +
CurationStatusuncurated  +
DefiningCitation4134212  +
DefinitionCartwheel cell bodies lie on the superfici Cartwheel cell bodies lie on the superficial side of the pyramidal (or fusiform) cell layer of the dorsal cochlear nucleus. Their spiny dendrites receive input from the axons of granule cells (parallel fibers) and their axons release GABA and glycine onto cartwheel, pyramidal and giant cell targets. Cartwheel cells share many of the features, molecular and electrophysiological, of cerebellar Purkinje neurons. iological, of cerebellar Purkinje neurons.
DendriteLocationMolecular layer of dorsal cochlear nucleus  +
FiringPatternsbursting  +
Has default formThis property is a special property in this wiki.Petilla neuron  +
Has roleIntrinsic neuron role  +
Idnifext_76  +
LabelCochlear nucleus (dorsal) cartwheel cell  +
Located inSomas lie at the superficial side of the pyramidal (fusiform) cell layer of the dorsal cochlear nucleus.  +
LocationOfLocalAxonArborizationPyramidal cells  +, Giant cells  +, and Cartwheel cells  +
ModifiedDate8 August 2013  +
MolecularConstituentsPEP19  +, Cerebellin  +, GAD  +, and GlyT2  +
NeurotransmitterGlycine  +, and GABA  +
NeurotransmitterReceptorsMGluR1alpha  +
OriginOfAxonsoma  +
Page has default formThis property is a special property in this wiki.Petilla neuron  +
RelatedToCerebellum Purkinje cell  +
SpeciesMammal  +
SpineDensityOnDendritesSpiny high density  +
SpontaneousFiringPatternsBursting  +
SpontaneousFiringRateRapid firing  +
SuperCategoryNeuron  +
SynonymCartwheel neuron  +