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Cyclopentolate

Name: Cyclopentolate
Description: A parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia. (PubChem) Pharmacology: Cyclopentolate is an anti-muscarinic in the same class as atropine and scopolamine. Cyclopentolate blocks the receptors in the muscles of the eye (muscarinic receptors). These receptors are involved controlling the pupil size and the shape of the lens. Cyclopentolate thus induces relaxation of the sphincter of the iris and the ciliary muscles. When applied topically to the eyes, it causes a rapid, intense cycloplegic and mydriatic effect that is maximal in 15 to 60 minutes; recovery usually occurs within 24 hours. The cycloplegic and mydriatic effects are slower in onset and longer in duration in patients who have dark pigmented irises. Mechanism of action: By blocking muscarinic receptors, cyclopentolate produces dilatation of the pupil (mydriasis) and prevents the eye from accommodating for near vision (cycloplegia). Drug type: Approved. Small Molecule. Drug category: Antimuscarinic eye preparations. Muscarinic Antagonists. Mydriatics. Parasympatholytics
Synonym(s): Ciclopentolato (INN-Spanish), Cyclopentoiate, Cyclopentolate HCL, Cyclopentolatum (INN-Latin), Cyclopentylate, Diopentolate, AK-Pentolate, Akpentolate, Cyclogyl, Cylate, Minims Cyclopentolate, Mydrilate, Ocu-Pentolate, Pentolair
Has role: Drug
Super-category: Molecular entity
URL: http://www.drugbank.ca/drugs/DB00979
*Id: DB00979
Related to: Cholinergic system, Muscarinic acetylcholine receptor M1
Link to OWL / RDF: Download this content as OWL/RDF


Contributors

Ayeliset, Ccdbuser, Nifbot2



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Facts about CyclopentolateRDF feed
Commenttaken from DrugBank
CurationStatusuncurated  +
CuratorAb  +
DefiningCitationhttp://www.drugbank.ca/drugs/DB00979  +
DefinitionA parasympatholytic anticholinergic used s A parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia. (PubChem) Pharmacology: Cyclopentolate is an anti-muscarinic in the same class as atropine and scopolamine. Cyclopentolate blocks the receptors in the muscles of the eye (muscarinic receptors). These receptors are involved controlling the pupil size and the shape of the lens. Cyclopentolate thus induces relaxation of the sphincter of the iris and the ciliary muscles. When applied topically to the eyes, it causes a rapid, intense cycloplegic and mydriatic effect that is maximal in 15 to 60 minutes; recovery usually occurs within 24 hours. The cycloplegic and mydriatic effects are slower in onset and longer in duration in patients who have dark pigmented irises. Mechanism of action: By blocking muscarinic receptors, cyclopentolate produces dilatation of the pupil (mydriasis) and prevents the eye from accommodating for near vision (cycloplegia). Drug type: Approved. Small Molecule. Drug category: Antimuscarinic eye preparations. Muscarinic Antagonists. Mydriatics. Parasympatholytics ntagonists. Mydriatics. Parasympatholytics
Has roleDrug  +
IdDB00979  +
LabelCyclopentolate  +
ModifiedDate14 April 2014  +
RelatedToCholinergic system  +, and Muscarinic acetylcholine receptor M1  +
SuperCategoryMolecular entity  +
SynonymCiclopentolato (INN-Spanish)  +, Cyclopentoiate  +, Cyclopentolate HCL  +, Cyclopentolatum (INN-Latin)  +, Cyclopentylate  +, Diopentolate  +, AK-Pentolate  +, Akpentolate  +, Cyclogyl  +, Cylate  +, Minims Cyclopentolate  +, Mydrilate  +, Ocu-Pentolate  +, and Pentolair  +