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D1 receptor
| Name: | D1 receptor |
| Description: | Dopamine receptor that stimulates adenylyl cyclase activity, and has a high affinity for SKF 38393 and its homologs. It is a protien that is encoded, in humans, by the DRD1 gene. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors are enriched in Caudate-putamen, nucleus accumbens, and olfactory tubercles. These receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. (adapted from Entrez Gene) |
| Synonym(s): | D1; D(1A) dopamine receptor, DRD1, D1 dopamine receptor, dopamine D1 receptor |
| Is part of: | Catecholamine system, Dopaminergic system |
| Related to: | Dopamine, Schizophrenia, D5 receptor |
| Has role: | Dopamine receptor, Neurotransmitter Receptor, G-protein coupled receptor |
| Abbreviation: | D1R |
| Super-category: | Protein |
| URL: | Entrez Gene |
| PMID: | PMID 215920 |
| Id: | nifext_5845 |
| Link to OWL / RDF: | Download this content as OWL/RDF |
Categories related to D1 receptor
Acetophenazine, Amantadine, Apomorphine, Carphenazine, Chlorprothixene, Clozapine, Cocaine, D5 receptor, Dopamine, Fenoldopam, Flupenthixol, Fluphenazine, Haloperidol, Levodopa, Lisuride, Loxapine, Methylergonovine, Minaprine, Olanzapine, Pegademase bovine, Pergolide, Perphenazine, Prochlorperazine, Promazine, Propiomazine, Quetiapine, Thiethylperazine, Thioridazine, Triflupromazine, Zuclopenthixol
Facts about D1 receptorRDF feed
| Abbrev | D1R + |
| Created | 19 September 2007 + |
| CurationStatus | uncurated + |
| DefiningCitation | Entrez Gene + |
| Definition | Dopamine receptor that stimulates adenylyl … Dopamine receptor that stimulates adenylyl cyclase activity, and has a high affinity for SKF 38393 and its homologs. It is a protien that is encoded, in humans, by the DRD1 gene. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors are enriched in Caudate-putamen, nucleus accumbens, and olfactory tubercles. These receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. (adapted from Entrez Gene) s of this gene. (adapted from Entrez Gene) |
| Has role | Dopamine receptor +, Neurotransmitter Receptor +, and G-protein coupled receptor + |
| Id | nifext_5845 + |
| Is part of | Catecholamine system +, and Dopaminergic system + |
| Label | D1 receptor + |
| ModifiedDate | 20 June 2012 + |
| PMID | 215920 + |
| RelatedTo | Dopamine +, Schizophrenia +, and D5 receptor + |
| SuperCategory | Protein + |
| Synonym | D1; D(1A) dopamine receptor +, DRD1 +, D1 dopamine receptor +, and dopamine D1 receptor + |