DBA

DBA

Name:	DBA
Super-category:	Inbred mouse strain
URL:	Beck, J.A., et al., Genealogies of mouse inbred strains (2000), Nature, Jan2000, v24, p23
Id:	birnlex_380
Link to OWL / RDF:	Download this content as OWL/RDF

Externally Sourced Definition: Origin: Little 1909 from stock segregating for coat colour. Oldest of all inbred strains of mice. In 1929-30 crosses were made between substrains, and several new substrains established, including the widely used substrains /1 and /2. Differences between the substrains are probably too large to be accounted for by mutation, and are probably due to substantial residual heterozygosity following the crosses between substrains. Thus DBA/1 and DBA/2 differ at least at the following loci: Car2, Ce2, Hc, H2, If1, Lsh, Tla, and Qa3. With such large differences, they should probably be regarded as different strains rather than substrains of the same strain. In this listing the two are listed separately. DBA/LiA differs from /1 and /2 at the Gpd1 locus, and is similar to DBA/2 at the Tla locus. Note that unfostered substrains carry the mammary tumour virus and have a high indicence of mammary tumours.

Contributors

This category has the following 3 subcategories, out of 3 total.

The following 2 pages are in this category, out of 2 total.

Facts about DBARDF feed

Created	15 August 2007 +
CurationStatus	pending_final_vetting +
DefiningCitation	Beck, J.A., et al., Genealogies of mouse inbred strains (2000), Nature, Jan2000, v24, p23 +
ExternallySourcedDefinition	Origin: Little 1909 from stock segregating … Origin: Little 1909 from stock segregating for coat colour. Oldest of all inbred strains of mice. In 1929-30 crosses were made between substrains, and several new substrains established, including the widely used substrains /1 and /2. Differences between the substrains are probably too large to be accounted for by mutation, and are probably due to substantial residual heterozygosity following the crosses between substrains. Thus DBA/1 and DBA/2 differ at least at the following loci: Car2, Ce2, Hc, H2, If1, Lsh, Tla, and Qa3. With such large differences, they should probably be regarded as different strains rather than substrains of the same strain. In this listing the two are listed separately. DBA/LiA differs from /1 and /2 at the Gpd1 locus, and is similar to DBA/2 at the Tla locus. Note that unfostered substrains carry the mammary tumour virus and have a high indicence of mammary tumours. have a high indicence of mammary tumours.
Id	birnlex_380 +
Label	DBA +
ModifiedDate	30 May 2009 +
SuperCategory	Inbred mouse strain +