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[[Category:]]
DJ-1 Mutant Drosophila
| Name: | DJ-1 Mutant Drosophila |
| Description: | This drosophila has had its the DJ-1 gene deleted. The DJ-1 mutant helps to protect the organism from oxidative stress. This fly model is viable, fertile, and has a normal number of dopaminergic neurons. However, it has increased sensitivity to oxidative stress and chemical agents. This mutant drosophila is being used in the laboratory to uncover the role of enviornmental toxins acting through oxdative stress on Parkinson's disease. |
| PMID: | PMID 16139213 |
| Id: | nlx_organ_090805 |
| Link to OWL / RDF: | Download this content as OWL/RDF |
Facts about DJ-1 Mutant DrosophilaRDF feed
| Authors | Marc Meulener +, Alexander Whitworth +, Cecilia Armstrong-Gold +, Patrizia Rizzu +, Peter Heutink +, Paul Wes +, Leo Pallanck +, and Nancy Bonini + |
| CurationStatus | uncurated + |
| Definition | This drosophila has had its the DJ-1 gene … This drosophila has had its the DJ-1 gene deleted. The DJ-1 mutant helps to protect the organism from oxidative stress. This fly model is viable, fertile, and has a normal number of dopaminergic neurons. However, it has increased sensitivity to oxidative stress and chemical agents. This mutant drosophila is being used in the laboratory to uncover the role of enviornmental toxins acting through oxdative stress on Parkinson's disease. gh oxdative stress on Parkinson's disease. |
| Id | nlx_organ_090805 + |
| JournalVolume | 15 + |
| Label | DJ-1 Mutant Drosophila + |
| ModifiedDate | 28 October 2009 + |
| PMID | 16139213 + |
| Pages | 1572-1577 |
| PublicationDate | September 6 +, and 2005 + |
| PublicationName | Current Biology + |
| Title | Drosophila DJ-1 Mutants Are Selectively Sensitive to Environmental Toxins Associated with Parkinson's Disease + |