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DJ-1 Mutant Drosophila

Name: DJ-1 Mutant Drosophila
Description: This drosophila has had its the DJ-1 gene deleted. The DJ-1 mutant helps to protect the organism from oxidative stress. This fly model is viable, fertile, and has a normal number of dopaminergic neurons. However, it has increased sensitivity to oxidative stress and chemical agents. This mutant drosophila is being used in the laboratory to uncover the role of enviornmental toxins acting through oxdative stress on Parkinson's disease.
PMID: PMID 16139213
Id: nlx_organ_090805
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Contributors

Laurenthompson214, Mimam



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Facts about DJ-1 Mutant DrosophilaRDF feed
AuthorsMarc Meulener  +, Alexander Whitworth  +, Cecilia Armstrong-Gold  +, Patrizia Rizzu  +, Peter Heutink  +, Paul Wes  +, Leo Pallanck  +, and Nancy Bonini  +
CurationStatusuncurated  +
DefinitionThis drosophila has had its the DJ-1 gene This drosophila has had its the DJ-1 gene deleted. The DJ-1 mutant helps to protect the organism from oxidative stress. This fly model is viable, fertile, and has a normal number of dopaminergic neurons. However, it has increased sensitivity to oxidative stress and chemical agents. This mutant drosophila is being used in the laboratory to uncover the role of enviornmental toxins acting through oxdative stress on Parkinson's disease. gh oxdative stress on Parkinson's disease.
Idnlx_organ_090805  +
JournalVolume15  +
LabelDJ-1 Mutant Drosophila  +
ModifiedDate28 October 2009  +
PMID16139213  +
Pages1572-1577
PublicationDateSeptember 6  +, and 2005  +
PublicationNameCurrent Biology  +
TitleDrosophila DJ-1 Mutants Are Selectively Sensitive to Environmental Toxins Associated with Parkinson's Disease  +