From NeuroLex
Dentate gyrus IS-I cell
| Name: | Dentate gyrus IS-I cell |
| Description: | The IS (Interneuron-Specific) subpopulation of interneurons have axons that exclusively innervate other interneurons. The Dentate gyrus IS-I class interneurons are visualized by immunostaining for Calretinin (CR) and establish multiple symmetrical synapses on the dendrites and somata of other CR-positive IS-I cells, Calbindin (CB) containing interneurons, and VIP-positive basket cells, but they do not innervate PV-containing interneurons. The dendrites of Dentate gyrus IS I neurons appear in all layers of Dentate gyrus and more characteristic feature of these dendrites is that they form long dendrodendritic junctions with each other. |
| Synonym(s): | DG Interneuron-specific cell |
| Abbreviation: | DG IS-I |
| Super-category: | neuron |
| URL: | p58 and p184. Andersen et al. "The Hippocampus Book" 2007; Freund & Buzsaki 1996 p374, PMID 8915675 |
| PMID: | PMID 8915675, 17093119 |
| Id: | nlx_cell_091203 |
| Defining criteria: | long dendrodendritic junctions, in which typically two to three dendrites are intermingled for more than 100µm; extremely specific in innervating other interneurons |
| Organism: | Vertebrata |
| Link to OWL / RDF: | Download this content as OWL/RDF |
Soma Specific Properties
| Soma Location: | Dentate gyrus |
Axon Specific Properties
| Location of distant axon arborization: | Dentate gyrus molecular layer, Dentate gyrus granule cell layer, Hilus of dentate gyrus |
Intrinsic Properties
| Neurotransmitter released: | GABA |
| Molecular constituents: | Calretinin |
| Defining Criteria: | long dendrodendritic junctions, in which typically two to three dendrites are intermingled for more than 100µm; extremely specific in innervating other interneurons |
Notes
This page uses this default form:Petilla_neuron
Facts about Dentate gyrus IS-I cellRDF feed
| Abbrev | DG IS-I + |
| CurationStatus | uncurated + |
| Curator | Sridevi Polavaram + |
| DefiningCitation | p58 and p184. Andersen et al. "The Hippocampus Book" 2007; Freund & Buzsaki 1996 p374, PMID 8915675 + |
| DefiningCriteria | long dendrodendritic junctions, in which typically two to three dendrites are intermingled for more than 100µm; extremely specific in innervating other interneurons + |
| Definition | The IS (Interneuron-Specific) subpopulatio … The IS (Interneuron-Specific) subpopulation of interneurons have axons that exclusively innervate other interneurons. The Dentate gyrus IS-I class interneurons are visualized by immunostaining for Calretinin (CR) and establish multiple symmetrical synapses on the dendrites and somata of other CR-positive IS-I cells, Calbindin (CB) containing interneurons, and VIP-positive basket cells, but they do not innervate PV-containing interneurons. The dendrites of Dentate gyrus IS I neurons appear in all layers of Dentate gyrus and more characteristic feature of these dendrites is that they form long dendrodendritic junctions with each other. dendrodendritic junctions with each other. |
| Has default formThis property is a special property in this wiki. | Petilla neuron + |
| ISBN | Andersen et al. 2007 p58, and p184 |
| Id | nlx_cell_091203 + |
| Label | Dentate gyrus IS-I cell + |
| Located in | Dentate gyrus + |
| LocationOfAxonArborization | Dentate gyrus molecular layer +, Dentate gyrus granule cell layer +, and Hilus of dentate gyrus + |
| ModifiedDate | 9 March 2012 + |
| MolecularConstituents | Calretinin + |
| Neurotransmitter | GABA + |
| PMID | 8915675, 17093119 + |
| Page has default formThis property is a special property in this wiki. | Petilla neuron + |
| Species | Vertebrata + |
| SuperCategory | neuron + |
| Synonym | DG Interneuron-specific cell + |



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