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Drosophila overexpressing Gprk2

Name: Drosophila overexpressing Gprk2
Description: This transgenic Drosophila coexpresses alpha-synuclein and G protein-coupled recepter kinase (Gprk2). Overexpression of Gprk2 increases phosphorylation at Ser129 and enhances alpha-synuclein toxicity.
Id: nlx_organ_090708
PMID: PMID 15834418
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Contributors

Laurenthompson214, Mimam



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Facts about Drosophila overexpressing Gprk2RDF feed
AuthorsLi Chen and Mel B Feany  +
CurationStatusuncurated  +
DefinitionThis transgenic Drosophila coexpresses alpha-synuclein and G protein-coupled recepter kinase (Gprk2). Overexpression of Gprk2 increases phosphorylation at Ser129 and enhances alpha-synuclein toxicity.
Figure2  +, and 3  +
Idnlx_organ_090708  +
JournalNumber5  +
JournalVolume8  +
LabelDrosophila overexpressing Gprk2  +
ModifiedDate28 October 2009  +
PMID15834418  +
Pages657-663
PublicationDateApril 17 2005  +
PublicationNameNature Neuroscience  +
TitleAlpha-Synuclein Phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson's disease  +