Category:Lewy Body-like Hyaline Inclusion
From NeuroLex
| Name: | Lewy Body-like Hyaline Inclusion |
| Definition: | In H&E preparations, neuronal LBHIs show an eosinphilic core with a paler peripheral halo, and their name is derived from their H&E staining features, which resemble those of Lewy bodies in patients with Parkinson's disease. Neuronal Lewy Body-like Hyaline Inclusions consist of filaments and granular materials, exhibit dense cores with rough preipheral halos and lack a limiting membrane. The filaments of these inclusions are composed of approximately 15-25 nm granule-coated fibrils in association with normal 10-nm neurofilaments. |
| Abbreviation | LBHI |
| Super-category: | Cellular Inclusion |
| Defining citation: | Kato S. 2008. Amyotrophic lateral sclerosis models and human neuropathology: similarities and differences. Acta Neuropathol 115:97-114. PMID 18026741 |
| Id: | nlx_169 |
| Link to OWLRDF: | Download this content as OWL/RDF |
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