Category:Lewy Body-like Hyaline Inclusion

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Lewy Body-like Hyaline Inclusion

Name:	Lewy Body-like Hyaline Inclusion
Definition:	In H&E preparations, neuronal LBHIs show an eosinphilic core with a paler peripheral halo, and their name is derived from their H&E staining features, which resemble those of Lewy bodies in patients with Parkinson's disease. Neuronal Lewy Body-like Hyaline Inclusions consist of filaments and granular materials, exhibit dense cores with rough preipheral halos and lack a limiting membrane. The filaments of these inclusions are composed of approximately 15-25 nm granule-coated fibrils in association with normal 10-nm neurofilaments.
Abbreviation:	LBHI
Super-category:	Cellular Inclusion
Defining citation:	Kato S. 2008. Amyotrophic lateral sclerosis models and human neuropathology: similarities and differences. Acta Neuropathol 115:97-114. PMID 18026741
Id:	nlx_169
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Abbrev	LBHI +
DefiningCitation	Kato S. 2008. Amyotrophic lateral sclerosis models and human neuropathology: similarities and differences. Acta Neuropathol 115:97-114. PMID 18026741 +
Definition	In H&E preparations, neuronal LBHIs show a … In H&E preparations, neuronal LBHIs show an eosinphilic core with a paler peripheral halo, and their name is derived from their H&E staining features, which resemble those of Lewy bodies in patients with Parkinson's disease. Neuronal Lewy Body-like Hyaline Inclusions consist of filaments and granular materials, exhibit dense cores with rough preipheral halos and lack a limiting membrane. The filaments of these inclusions are composed of approximately 15-25 nm granule-coated fibrils in association with normal 10-nm neurofilaments. ociation with normal 10-nm neurofilaments.
Id	nlx_169 +
Label	Lewy Body-like Hyaline Inclusion +
ModifiedDate	30 May 2009 +