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Metabotropic Glutamate Receptor

Name: Metabotropic Glutamate Receptor
Description: The metabotropic glutamate receptors, or mGluRs, are a type of glutamate receptor which are active through an indirect metabotropic process. They are members of the group C family of G-protein-coupled receptors, or GPCRs, and are divided into 3 groups based on sequence homology and binding affinities. Like all glutamate receptors, mGluRs bind to glutamate, an amino acid that functions as an excitatory neurotransmitter.

Group I mGluR's are coupled to phospholipid metabolism and comprise members 1 and 5

Group II mGluR's are coupled to reduced cAMP turnover and comprise members 2, 3 and 4

Group III mGluR's are coupled to reduced cAMP turnover and comprise members 6, 7, and 8
Synonym(s): mGluRs, GRM, Glutamate metabotropic, Metabotropic glutamate
Abbreviation: mGluR
Has role: Glutamate receptor
Super-category: G-protein_coupled_receptor
*Id: nlx_mol_20090503
Related to: Glutamate, Aspartate
Link to OWL / RDF: Download this content as OWL/RDF


Contributors

Admin, Bandrow, Mimam, Nifbot2

Subcategories

This category has the following 9 subcategories, out of 9 total.

M

M cont.

M cont.



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*Note: Neurolex imports many terms and their ids from existing community ontologies, e.g., the Gene Ontology. Neurolex, however, is a dynamic site and any content beyond the identifier should not be presumed to reflect the content or views of the source ontology. Users should consult with the authoritative source for each ontology for current information.

Facts about Metabotropic Glutamate ReceptorRDF feed
AbbrevmGluR  +
CurationStatusuncurated  +
DefinitionThe metabotropic glutamate receptors, or m The metabotropic glutamate receptors, or mGluRs, are a type of glutamate receptor which are active through an indirect metabotropic process. They are members of the group C family of G-protein-coupled receptors, or GPCRs, and are divided into 3 groups based on sequence homology and binding affinities. Like all glutamate receptors, mGluRs bind to glutamate, an amino acid that functions as an excitatory neurotransmitter.

Group I mGluR's are coupled to phospholipid metabolism and comprise members 1 and 5

Group II mGluR's are coupled to reduced cAMP turnover and comprise members 2, 3 and 4

Group III mGluR's are coupled to reduced cAMP turnover and comprise members 6, 7, and 8
turnover and comprise members 6, 7, and 8
Has roleGlutamate receptor  +
Idnlx_mol_20090503  +
LabelMetabotropic Glutamate Receptor  +
ModifiedDate30 December 2009  +
RelatedToGlutamate  +, and Aspartate  +
SuperCategoryG-protein_coupled_receptor  +
SynonymmGluRs  +, GRM  +, Glutamate metabotropic  +, and Metabotropic glutamate  +