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Metabotropic Glutamate Receptor

Name: Metabotropic Glutamate Receptor
Description: The metabotropic glutamate receptors, or mGluRs, are a type of glutamate receptor which are active through an indirect metabotropic process. They are members of the group C family of G-protein-coupled receptors, or GPCRs, and are divided into 3 groups based on sequence homology and binding affinities. Like all glutamate receptors, mGluRs bind to glutamate, an amino acid that functions as an excitatory neurotransmitter.

Group I mGluR's are coupled to phospholipid metabolism and comprise members 1 and 5

Group II mGluR's are coupled to reduced cAMP turnover and comprise members 2, 3 and 4

Group III mGluR's are coupled to reduced cAMP turnover and comprise members 6, 7, and 8
Synonym(s): mGluRs, GRM, Glutamate metabotropic, Metabotropic glutamate
Related to: Glutamate, Aspartate
Has role: Glutamate receptor
Abbreviation: mGluR
Super-category: G-protein_coupled_receptor
Id: nlx_mol_20090503
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Contributors

Admin, Bandrow, Mimam, Nifbot2

Subcategories

This category has the following 9 subcategories, out of 9 total.

M

M cont.

M cont.



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Facts about Metabotropic Glutamate ReceptorRDF feed
AbbrevmGluR  +
CurationStatusuncurated  +
DefinitionThe metabotropic glutamate receptors, or m The metabotropic glutamate receptors, or mGluRs, are a type of glutamate receptor which are active through an indirect metabotropic process. They are members of the group C family of G-protein-coupled receptors, or GPCRs, and are divided into 3 groups based on sequence homology and binding affinities. Like all glutamate receptors, mGluRs bind to glutamate, an amino acid that functions as an excitatory neurotransmitter.

Group I mGluR's are coupled to phospholipid metabolism and comprise members 1 and 5

Group II mGluR's are coupled to reduced cAMP turnover and comprise members 2, 3 and 4

Group III mGluR's are coupled to reduced cAMP turnover and comprise members 6, 7, and 8
turnover and comprise members 6, 7, and 8
Has roleGlutamate receptor  +
Idnlx_mol_20090503  +
LabelMetabotropic Glutamate Receptor  +
ModifiedDate30 December 2009  +
RelatedToGlutamate  +, and Aspartate  +
SuperCategoryG-protein_coupled_receptor  +
SynonymmGluRs  +, GRM  +, Glutamate metabotropic  +, and Metabotropic glutamate  +