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NMDA-type glutamate-gated cationic channel

Name: NMDA-type glutamate-gated cationic channel
Description: Tetrameric receptor, consisting of two glycine binding NR1 subunits and two glutamate binding NR2 subunits. The glycine-binding NR3 subunits can also assemble with NR2 subunits. NR1 and NR3 subunits assemble only in xenopus oocytes to form a glycine gated receptor.

NMDA receptors bind glutamate, aspartate, NMDA, NMDA receptors' conductance is modified by glycine, Magnesium, Zinc and 2-amino-5-phosphonovalerate (APV)

Laube et al., suggest that the recombinant NMDA receptor is a tetramer (PMID: 9526012, also see PMID: 18779583).
Synonym(s): NMDA receptor, NMDA, NMDAR
Has role: Neurotransmitter Receptor, Glutamate receptor, Ionotropic Glutamate Receptor
Super-category: Glutamate-gated cationic channel
*Id: nifext_5250
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*Note: Neurolex imports many terms and their ids from existing community ontologies, e.g., the Gene Ontology. Neurolex, however, is a dynamic site and any content beyond the identifier should not be presumed to reflect the content or views of the source ontology. Users should consult with the authoritative source for each ontology for current information.

Facts about NMDA-type glutamate-gated cationic channelRDF feed
Created19 September 2007  +
CurationStatusuncurated  +
DefinitionTetrameric receptor, consisting of two gly Tetrameric receptor, consisting of two glycine binding NR1 subunits and two glutamate binding NR2 subunits. The glycine-binding NR3 subunits can also assemble with NR2 subunits. NR1 and NR3 subunits assemble only in xenopus oocytes to form a glycine gated receptor.

NMDA receptors bind glutamate, aspartate, NMDA, NMDA receptors' conductance is modified by glycine, Magnesium, Zinc and 2-amino-5-phosphonovalerate (APV)

Laube et al., suggest that the recombinant NMDA receptor is a tetramer (PMID: 9526012, also see PMID: 18779583).
(PMID: 9526012, also see PMID: 18779583).
Has roleNeurotransmitter Receptor  +, Glutamate receptor  +, and Ionotropic Glutamate Receptor  +
Idnifext_5250  +
LabelNMDA-type glutamate-gated cationic channel  +
ModifiedDate29 December 2009  +
SuperCategoryGlutamate-gated cationic channel  +
SynonymNMDA receptor  +, NMDA  +, and NMDAR  +