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NMDA-type glutamate-gated cationic channel

Name: NMDA-type glutamate-gated cationic channel
Description: Tetrameric receptor, consisting of two glycine binding NR1 subunits and two glutamate binding NR2 subunits. The glycine-binding NR3 subunits can also assemble with NR2 subunits. NR1 and NR3 subunits assemble only in xenopus oocytes to form a glycine gated receptor.

NMDA receptors bind glutamate, aspartate, NMDA, NMDA receptors' conductance is modified by glycine, Magnesium, Zinc and 2-amino-5-phosphonovalerate (APV)

Laube et al., suggest that the recombinant NMDA receptor is a tetramer (PMID: 9526012, also see PMID: 18779583).
Synonym(s): NMDA receptor, NMDA, NMDAR
Has role: Neurotransmitter Receptor, Glutamate receptor, Ionotropic Glutamate Receptor
Super-category: Glutamate-gated cationic channel
Id: nifext_5250
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Facts about NMDA-type glutamate-gated cationic channelRDF feed
Created19 September 2007  +
CurationStatusuncurated  +
DefinitionTetrameric receptor, consisting of two gly Tetrameric receptor, consisting of two glycine binding NR1 subunits and two glutamate binding NR2 subunits. The glycine-binding NR3 subunits can also assemble with NR2 subunits. NR1 and NR3 subunits assemble only in xenopus oocytes to form a glycine gated receptor.

NMDA receptors bind glutamate, aspartate, NMDA, NMDA receptors' conductance is modified by glycine, Magnesium, Zinc and 2-amino-5-phosphonovalerate (APV)

Laube et al., suggest that the recombinant NMDA receptor is a tetramer (PMID: 9526012, also see PMID: 18779583).
(PMID: 9526012, also see PMID: 18779583).
Has roleNeurotransmitter Receptor  +, Glutamate receptor  +, and Ionotropic Glutamate Receptor  +
Idnifext_5250  +
LabelNMDA-type glutamate-gated cationic channel  +
ModifiedDate29 December 2009  +
SuperCategoryGlutamate-gated cationic channel  +
SynonymNMDA receptor  +, NMDA  +, and NMDAR  +