EditFrom NeuroLex
NMDA-type glutamate-gated cationic channel
| Name: | NMDA-type glutamate-gated cationic channel |
| Description: | Tetrameric receptor, consisting of two glycine binding NR1 subunits and two glutamate binding NR2 subunits. The glycine-binding NR3 subunits can also assemble with NR2 subunits. NR1 and NR3 subunits assemble only in xenopus oocytes to form a glycine gated receptor.
NMDA receptors bind glutamate, aspartate, NMDA, NMDA receptors' conductance is modified by glycine, Magnesium, Zinc and 2-amino-5-phosphonovalerate (APV) Laube et al., suggest that the recombinant NMDA receptor is a tetramer (PMID: 9526012, also see PMID: 18779583). |
| Synonym(s): | NMDA receptor, NMDA, NMDAR |
| Has role: | Neurotransmitter Receptor, Glutamate receptor, Ionotropic Glutamate Receptor |
| Super-category: | Glutamate-gated cationic channel |
| Id: | nifext_5250 |
| Link to OWL / RDF: | Download this content as OWL/RDF |
Facts about NMDA-type glutamate-gated cationic channelRDF feed
| Created | 19 September 2007 + |
| CurationStatus | uncurated + |
| Definition | Tetrameric receptor, consisting of two gly … Tetrameric receptor, consisting of two glycine binding NR1 subunits and two glutamate binding NR2 subunits. The glycine-binding NR3 subunits can also assemble with NR2 subunits. NR1 and NR3 subunits assemble only in xenopus oocytes to form a glycine gated receptor.
NMDA receptors bind glutamate, aspartate, NMDA, NMDA receptors' conductance is modified by glycine, Magnesium, Zinc and 2-amino-5-phosphonovalerate (APV) Laube et al., suggest that the recombinant NMDA receptor is a tetramer (PMID: 9526012, also see PMID: 18779583). (PMID: 9526012, also see PMID: 18779583). |
| Has role | Neurotransmitter Receptor +, Glutamate receptor +, and Ionotropic Glutamate Receptor + |
| Id | nifext_5250 + |
| Label | NMDA-type glutamate-gated cationic channel + |
| ModifiedDate | 29 December 2009 + |
| SuperCategory | Glutamate-gated cationic channel + |
| Synonym | NMDA receptor +, NMDA +, and NMDAR + |