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Neocortex pyramidal cell layer 5-6

Name: Neocortex pyramidal cell layer 5-6
Description: The pyramidal cell of layer 5 of the neocortex has a pyramidal-shaped cell body which gives off a number of laterally-directed basal dendrites and usually a single apical dendrite which ascends to branch and terminate in layer 1; these dendrites are covered in dendritic spines. The axon descends through the internal capsule, giving off collaterals to the thalamus, to the medullary pyramids, where most of the axons cross controlaterally to descend and innervate the ventral horn of the spinal cord.
Synonym(s): deep pyramidal cell, Neocortex pyramidal neuron layer 5-6, Layer 5-6 pyramidal cell, layer 5 pyramidal neuron, layer 5 pyramidal cell, Tufted layer 5 (TL5) pyramidal neurons[1]
Abbreviation: TL5[1]
Has role: Principal neuron role
Super-category: Neuron
*Id: nifext_50
Defining criteria: Basal and apical dendrites; soma in neocortical layer 5
Organism: Mammal
Link to OWL / RDF: Download this content as OWL/RDF

Soma Specific Properties

Cell Soma Shape: Pyramidal
Cell Soma Size: Large soma
Soma Location: Neocortex layer 5, Neocortex layer 6

Dendrite Specific Properties

Spine density on dendrites: spiny high density
Branching type: apical/basal

Axon Specific Properties

Axon myelination: myelinated
Axon projection laterality: ipsilateral
Origin of axon: soma
Location of distant axon arborization: contralateral, ipsilateral spinal cord ventral horn
Location of local axon arborization: Neocortex layer 6

Intrinsic Properties

Neurotransmitter released: Glutamate
Neurotransmitter receptors: GABA-gated anionic channel, AMPA-type glutamate-gated cationic channel, NMDA-type glutamate-gated cationic channel
Defining Criteria: Basal and apical dendrites; soma in neocortical layer 5


References

  1. 1.0 1.1 Markram H (1997) A network of tufted layer 5 pyramidal neurons. Cereb Cortex 7: 523-33 PubMed

Notes

This page uses this default form:Petilla_neuron

Schema information for category "Neocortex pyramidal cell layer 5-6"

Properties

PropertyRange/Type
Surface area +Number


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Facts about Neocortex pyramidal cell layer 5-6RDF feed
AbbrevTL5  +
AxonLengthPyramidal tract axon: 15-20 mm  +
AxonMyelinationmyelinated  +
AxonProjectionLateralityipsilateral  +
BranchingMetricsapical/basal  +
CellSomaShapeCategory:Pyramidal   +
CellSomaSizeLarge soma  +
CellularSynapticTargetRat: Spinal cord interneurons  +, and Presynaptic to spinal motoneurons.  +
CommentThe data are for a pyramidal tract neuron in layer 5 of the motor strip of the neocortex of the rat (GS)
Created5 September 2007  +
CurationStatusuncurated  +
DefiningCriteriaBasal and apical dendrites; soma in neocortical layer 5  +
DefinitionThe pyramidal cell of layer 5 of the neoco The pyramidal cell of layer 5 of the neocortex has a pyramidal-shaped cell body which gives off a number of laterally-directed basal dendrites and usually a single apical dendrite which ascends to branch and terminate in layer 1; these dendrites are covered in dendritic spines. The axon descends through the internal capsule, giving off collaterals to the thalamus, to the medullary pyramids, where most of the axons cross controlaterally to descend and innervate the ventral horn of the spinal cord. rvate the ventral horn of the spinal cord.
DendriteThicknessRat: Basal trunks: 3-5 um; Apical trunk: 4-7 um  +
FiringPatternsRegular firing and bursting  +
Has default formThis property is a special property in this wiki.Petilla neuron  +
Has rolePrincipal neuron role  +
Idnifext_50  +
LabelNeocortex pyramidal cell layer 5-6  +
Located inNeocortex layer 5  +, and Neocortex layer 6  +
LocationOfAxonArborizationContralateral  +, and Ipsilateral spinal cord ventral horn  +
LocationOfLocalAxonArborizationNeocortex layer 6  +
ModifiedDate4 June 2013  +
NeurotransmitterGlutamate  +
NeurotransmitterReceptorsGABA-gated anionic channel  +, AMPA-type glutamate-gated cationic channel  +, and NMDA-type glutamate-gated cationic channel  +
NumberOfPrimaryDendrites1-2, plus basal (lateral) dendrites  +
OriginOfAxonsoma  +
Page has default formThis property is a special property in this wiki.Petilla neuron  +
SpeciesMammal  +
SpineDensityOnDendritesSpiny high density  +
SpontaneousFiringPatternsRegular firing and bursting  +
SpontaneousFiringRatemedium firing  +
SubcellularSynapticTargetDendrites of spinal cord interneurons  +
SuperCategoryNeuron  +
Synonymdeep pyramidal cell  +, Neocortex pyramidal neuron layer 5-6  +, Layer 5-6 pyramidal cell  +, layer 5 pyramidal neuron  +, layer 5 pyramidal cell  +, and Tufted layer 5 (TL5) pyramidal neurons  +