EditFrom NeuroLex
Neocortex pyramidal cell layer 5-6
| Name: | Neocortex pyramidal cell layer 5-6 |
| Description: | The pyramidal cell of layer 5 of the neocortex has a pyramidal-shaped cell body which gives off a number of laterally-directed basal dendrites and usually a single apical dendrite which ascends to branch and terminate in layer 1; these dendrites are covered in dendritic spines. The axon descends through the internal capsule, giving off collaterals to the thalamus, to the medullary pyramids, where most of the axons cross controlaterally to descend and innervate the ventral horn of the spinal cord. |
| Synonym(s): | deep pyramidal cell, Neocortex pyramidal neuron layer 5-6, Layer 5-6 pyramidal cell, layer 5 pyramidal neuron, layer 5 pyramidal cell, Tufted layer 5 (TL5) pyramidal neurons[1] |
| Has role: | Principal neuron role |
| Abbreviation: | TL5[1] |
| Super-category: | Neuron |
| Id: | nifext_50 |
| Defining criteria: | Basal and apical dendrites; soma in neocortical layer 5 |
| Organism: | Mammal |
| Link to OWL / RDF: | Download this content as OWL/RDF |
Soma Specific Properties
| Cell Soma Shape: | Pyramidal |
| Cell Soma Size: | Large soma |
| Soma Location: | Neocortex layer 5, Neocortex layer 6 |
Dendrite Specific Properties
| Spine density on dendrites: | spiny high density |
| Branching type: | apical/basal |
Axon Specific Properties
Intrinsic Properties
| Neurotransmitter released: | Glutamate |
| Neurotransmitter receptors: | GABA-gated anionic channel, AMPA-type glutamate-gated cationic channel, NMDA-type glutamate-gated cationic channel |
| Defining Criteria: | Basal and apical dendrites; soma in neocortical layer 5 |
References
- ↑ 1.0 1.1 Markram H (1997) A network of tufted layer 5 pyramidal neurons. Cereb Cortex 7: 523-33 PubMed
Notes
This page uses this default form:Petilla_neuron
Schema information for category "Neocortex pyramidal cell layer 5-6"
Properties
| Property | Range/Type |
|---|---|
| Surface area + | Number |
Facts about Neocortex pyramidal cell layer 5-6RDF feed
| Abbrev | TL5 + |
| AxonLength | Pyramidal tract axon: 15-20 mm + |
| AxonMyelination | myelinated + |
| AxonProjectionLaterality | ipsilateral + |
| BranchingMetrics | apical/basal + |
| CellSomaShape | Category:Pyramidal + |
| CellSomaSize | Large soma + |
| CellularSynapticTarget | Rat: Spinal cord interneurons +, and Presynaptic to spinal motoneurons. + |
| Comment | The data are for a pyramidal tract neuron in layer 5 of the motor strip of the neocortex of the rat (GS) |
| Created | 5 September 2007 + |
| CurationStatus | uncurated + |
| DefiningCriteria | Basal and apical dendrites; soma in neocortical layer 5 + |
| Definition | The pyramidal cell of layer 5 of the neoco … The pyramidal cell of layer 5 of the neocortex has a pyramidal-shaped cell body which gives off a number of laterally-directed basal dendrites and usually a single apical dendrite which ascends to branch and terminate in layer 1; these dendrites are covered in dendritic spines. The axon descends through the internal capsule, giving off collaterals to the thalamus, to the medullary pyramids, where most of the axons cross controlaterally to descend and innervate the ventral horn of the spinal cord. rvate the ventral horn of the spinal cord. |
| DendriteThickness | Rat: Basal trunks: 3-5 um; Apical trunk: 4-7 um + |
| FiringPatterns | Regular firing and bursting + |
| Has default formThis property is a special property in this wiki. | Petilla neuron + |
| Has role | Principal neuron role + |
| Id | nifext_50 + |
| Label | Neocortex pyramidal cell layer 5-6 + |
| Located in | Neocortex layer 5 +, and Neocortex layer 6 + |
| LocationOfAxonArborization | Contralateral +, and Ipsilateral spinal cord ventral horn + |
| LocationOfLocalAxonArborization | Neocortex layer 6 + |
| ModifiedDate | 4 June 2013 + |
| Neurotransmitter | Glutamate + |
| NeurotransmitterReceptors | GABA-gated anionic channel +, AMPA-type glutamate-gated cationic channel +, and NMDA-type glutamate-gated cationic channel + |
| NumberOfPrimaryDendrites | 1-2, plus basal (lateral) dendrites + |
| OriginOfAxon | soma + |
| Page has default formThis property is a special property in this wiki. | Petilla neuron + |
| Species | Mammal + |
| SpineDensityOnDendrites | Spiny high density + |
| SpontaneousFiringPatterns | Regular firing and bursting + |
| SpontaneousFiringRate | medium firing + |
| SubcellularSynapticTarget | Dendrites of spinal cord interneurons + |
| SuperCategory | Neuron + |
| Synonym | deep pyramidal cell +, Neocortex pyramidal neuron layer 5-6 +, Layer 5-6 pyramidal cell +, layer 5 pyramidal neuron +, layer 5 pyramidal cell +, and Tufted layer 5 (TL5) pyramidal neurons + |