arrow

From NeuroLex

Jump to: navigation, search



Neocortex pyramidal layer 2-3 cell

Name: Neocortex pyramidal layer 2-3 cell
Description: This basic excitatory neuron type has a pyramidal-shaped cell body, with apical and basal dendrites. Typically, there is an axon that projects to other cortical and/or subcortical areas, as well as giving rise to local collaterals.
Synonym(s): corticocortical cell, superficial pyramidal cell, Neocortex pyramidal neuron layer 2-3, Layer 2-3 pyramidal cell, Neocortical pyramidal neuron: superficial, deep layer (layer 5, 6) pyramidal cell
Has role: Principal neuron role
Super-category: Neocortex pyramidal cell
*Id: nifext_49
Organism: Vertebrata
Link to OWL / RDF: Download this content as OWL/RDF

Soma Specific Properties

Cell Soma Shape: Pyramidal
Cell Soma Size: Medium soma
Soma Location: Neocortex, Neocortex layer 2, Neocortex layer 3, Neocortex layer 5, Neocortex layer 6, Neocortex layer 4

Dendrite Specific Properties

Dendrite location: basal dendrites will be in the same layer as the soma and/or the subjacent layer. Apical dendrites rise toward the pia and into layer 1. For layer 6 neurons, however, the apical dendrite will often not continue beyond layer 4/lower layer 3.
Spine density on dendrites: spiny high density
Branching type: apical/basal

Axon Specific Properties

Axon myelination: myelinated
Axon projection laterality: bilateral
Origin of axon: soma
Location of distant axon arborization: For supragranular neurons, this is almost exclusively cortical (except for some corticostriatal projections from layer 3). Infragranular neurons can project subcortically (LGN, superior colliculus, claustrum, amygdala) but also cortically, ipsi- or contralateral.
Location of local axon arborization: For layer 6: layer 6 and 4 (J.S. Lund, in primate and see A. Thomson for rodent); for layer 5: largely layer 5 but can extend to layer 3; for layer 3, largely layer 3, but can extend to layer 5; layer 2, layer 2, but can involve other layers.

Intrinsic Properties

Neurotransmitter released: glutamate
Neurotransmitter receptors: ?
Molecular constituents: ?


Notes

This page uses this default form:Petilla_neuron

  • can be some "ectopic" pyramids in layer 4


bookmark

*Note: Neurolex imports many terms and their ids from existing community ontologies, e.g., the Gene Ontology. Neurolex, however, is a dynamic site and any content beyond the identifier should not be presumed to reflect the content or views of the source ontology. Users should consult with the authoritative source for each ontology for current information.

Facts about Neocortex pyramidal layer 2-3 cellRDF feed
AxonMyelinationmyelinated  +
AxonProjectionLateralitybilateral  +
BranchingMetricsapical/basal  +
CellSomaShapeCategory:Pyramidal   +
CellSomaSizeMedium soma  +
CommentWe question whether this definition is for the layer 2-3 pyramidal cell or just the neocortex pyramidal cell. Review is necessary
Created5 September 2007  +
CurationStatusgraph position temporary  +
CuratorMaryann Martone  +, and Giorgio Ascoli  +
DefinitionThis basic excitatory neuron type has a pyramidal-shaped cell body, with apical and basal dendrites. Typically, there is an axon that projects to other cortical and/or subcortical areas, as well as giving rise to local collaterals.
DendriteLocationBasal dendrites will be in the same layer as the soma and/or the subjacent layer. Apical dendrites rise toward the pia and into layer 1. For layer 6 neurons  +, However  +, and The apical dendrite will often not continue beyond layer 4/lower layer 3.  +
Has default formThis property is a special property in this wiki.Petilla neuron  +
Has rolePrincipal neuron role  +
Idnifext_49  +
LabelNeocortex pyramidal layer 2-3 cell  +
Located inNeocortex  +, Neocortex layer 2  +, Neocortex layer 3  +, Neocortex layer 5  +, Neocortex layer 6  +, and Neocortex layer 4  +
LocationOfAxonArborizationFor supragranular neurons  +, This is almost exclusively cortical (except for some corticostriatal projections from layer 3). Infragranular neurons can project subcortically (LGN  +, Superior colliculus  +, Claustrum  +, Amygdala) but also cortically  +, and Ipsi- or contralateral.  +
LocationOfLocalAxonArborizationFor layer 6: layer 6 and 4 (J.S. Lund  +, In primate and see A. Thomson for rodent); for layer 5: largely layer 5 but can extend to layer 3; for layer 3  +, Largely layer 3  +, But can extend to layer 5; layer 2  +, Layer 2  +, and But can involve other layers.  +
ModifiedDate26 July 2013  +
MolecularConstituents?  +
NeurotransmitterGlutamate  +
NeurotransmitterReceptors?  +
OriginOfAxonsoma  +
Page has default formThis property is a special property in this wiki.Petilla neuron  +
SpeciesVertebrata  +
SpineDensityOnDendritesSpiny high density  +
SuperCategoryNeocortex pyramidal cell  +
Synonymcorticocortical cell  +, superficial pyramidal cell  +, Neocortex pyramidal neuron layer 2-3  +, Layer 2-3 pyramidal cell  +, Neocortical pyramidal neuron: superficial  +, deep layer (layer 5  +, and 6) pyramidal cell  +