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Neocortex pyramidal layer 2-3 cell

Name: Neocortex pyramidal layer 2-3 cell
Description: This basic excitatory neuron type has a pyramidal-shaped cell body, with apical and basal dendrites. Typically, there is an axon that projects to other cortical and/or subcortical areas, as well as giving rise to local collaterals.
Synonym(s): corticocortical cell, superficial pyramidal cell, Neocortex pyramidal neuron layer 2-3, Layer 2-3 pyramidal cell, Neocortical pyramidal neuron: superficial, deep layer (layer 5, 6) pyramidal cell
Has role: Principal neuron role
Super-category: Neocortex pyramidal cell
Id: nifext_49
Organism: Vertebrata
Link to OWL / RDF: Download this content as OWL/RDF

Soma Specific Properties

Cell Soma Shape: Pyramidal
Cell Soma Size: Medium soma
Soma Location: Neocortex, Neocortex layer 2, Neocortex layer 3, Neocortex layer 5, Neocortex layer 6, Neocortex layer 4

Dendrite Specific Properties

Dendrite location: basal dendrites will be in the same layer as the soma and/or the subjacent layer. Apical dendrites rise toward the pia and into layer 1. For layer 6 neurons, however, the apical dendrite will often not continue beyond layer 4/lower layer 3.
Spine density on dendrites: spiny high density
Branching type: apical/basal

Axon Specific Properties

Axon myelination: myelinated
Axon projection laterality: bilateral
Origin of axon: soma
Location of distant axon arborization: For supragranular neurons, this is almost exclusively cortical (except for some corticostriatal projections from layer 3). Infragranular neurons can project subcortically (LGN, superior colliculus, claustrum, amygdala) but also cortically, ipsi- or contralateral.
Location of local axon arborization: For layer 6: layer 6 and 4 (J.S. Lund, in primate and see A. Thomson for rodent); for layer 5: largely layer 5 but can extend to layer 3; for layer 3, largely layer 3, but can extend to layer 5; layer 2, layer 2, but can involve other layers.

Intrinsic Properties

Neurotransmitter released: glutamate
Neurotransmitter receptors: ?
Molecular constituents: ?


Notes

This page uses this default form:Petilla_neuron

  • can be some "ectopic" pyramids in layer 4


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Facts about Neocortex pyramidal layer 2-3 cellRDF feed
AxonMyelinationmyelinated  +
AxonProjectionLateralitybilateral  +
BranchingMetricsapical/basal  +
CellSomaShapeCategory:Pyramidal   +
CellSomaSizeMedium soma  +
CommentWe question whether this definition is for the layer 2-3 pyramidal cell or just the neocortex pyramidal cell. Review is necessary
Created5 September 2007  +
CurationStatusgraph position temporary  +
CuratorMaryann Martone  +, and Giorgio Ascoli  +
DefinitionThis basic excitatory neuron type has a pyramidal-shaped cell body, with apical and basal dendrites. Typically, there is an axon that projects to other cortical and/or subcortical areas, as well as giving rise to local collaterals.
DendriteLocationBasal dendrites will be in the same layer as the soma and/or the subjacent layer. Apical dendrites rise toward the pia and into layer 1. For layer 6 neurons  +, However  +, and The apical dendrite will often not continue beyond layer 4/lower layer 3.  +
Has default formThis property is a special property in this wiki.Petilla neuron  +
Has rolePrincipal neuron role  +
Idnifext_49  +
LabelNeocortex pyramidal layer 2-3 cell  +
Located inNeocortex  +, Neocortex layer 2  +, Neocortex layer 3  +, Neocortex layer 5  +, Neocortex layer 6  +, and Neocortex layer 4  +
LocationOfAxonArborizationFor supragranular neurons  +, This is almost exclusively cortical (except for some corticostriatal projections from layer 3). Infragranular neurons can project subcortically (LGN  +, Superior colliculus  +, Claustrum  +, Amygdala) but also cortically  +, and Ipsi- or contralateral.  +
LocationOfLocalAxonArborizationFor layer 6: layer 6 and 4 (J.S. Lund  +, In primate and see A. Thomson for rodent); for layer 5: largely layer 5 but can extend to layer 3; for layer 3  +, Largely layer 3  +, But can extend to layer 5; layer 2  +, Layer 2  +, and But can involve other layers.  +
ModifiedDate26 July 2013  +
MolecularConstituents?  +
NeurotransmitterGlutamate  +
NeurotransmitterReceptors?  +
OriginOfAxonsoma  +
Page has default formThis property is a special property in this wiki.Petilla neuron  +
SpeciesVertebrata  +
SpineDensityOnDendritesSpiny high density  +
SuperCategoryNeocortex pyramidal cell  +
Synonymcorticocortical cell  +, superficial pyramidal cell  +, Neocortex pyramidal neuron layer 2-3  +, Layer 2-3 pyramidal cell  +, Neocortical pyramidal neuron: superficial  +, deep layer (layer 5  +, and 6) pyramidal cell  +