Neostriatum direct pathway spiny neuron

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This is the latest sighted revision, approved on 1 July 2012. The draft has 1 change awaiting review.

Name:	Neostriatum direct pathway spiny neuron
Description:	The principal projection neuron of the caudate and putamen.^[1]
Synonym(s):	Medium spiny neuron, Neostriatal spiny neuron, Medium-sized spiny neuron, Striatal spiny neuron, Striatal medium spiny neuron
Has role:	Principal neuron role
Abbreviation:	MSN
Super-category:	Neuron
URL:	Kemp and Powell,
Id:	nlx_149135
Organism:	Mammal
Link to OWL / RDF:	Download this content as OWL/RDF

Soma Specific Properties

Cell Soma Shape:	Multipolar
Cell Soma Size:	Medium soma
Soma Location:	Caudate nucleus, Putamen, Nucleus accumbens

Dendrite Specific Properties

Spine density on dendrites:	spiny high density

Axon Specific Properties

Axon myelination:	myelinated
Axon projection laterality:	ipsilateral
Origin of axon:	soma and sometimes dendrite
Location of distant axon arborization:	Globus pallidus internal segment, Globus pallidus external segment, Substantia nigra
Location of local axon arborization:	Striosomal compartment of neostriatum, Matrix compartment of neostriatum

Intrinsic Properties

Neurotransmitter released:	GABA
Neurotransmitter receptors:	D1 receptor, AMPA-type glutamate-gated cationic channel, D2 receptor
Molecular constituents:	Enkephalin, Substance P

References

↑ Wilson CJ & Groves PM (1980) Fine structure and synaptic connections of the common spiny neuron of the rat neostriatum: a study employing intracellular inject of horseradish peroxidase. J Comp Neurol 194: 599-615 PubMed

This page uses this default form:Petilla_neuron

Abbrev	MSN +
AxonMyelination	myelinated +
AxonProjectionLaterality	ipsilateral +
CellSomaShape	Category:Multipolar +
CellSomaSize	Medium soma +
Comment	This class is duplicated in NIF
CurationStatus	uncurated +
DefiningCitation	Kemp and Powell, +
Definition	The principal projection neuron of the caudate and putamen.
DendriteThickness	2-3 um +
EditorialNote	http://senselab.med.yale.edu/neurondb/NeuronProp.aspx?id=260
Has default formThis property is a special property in this wiki.	Petilla neuron +
Has role	Principal neuron role +
Id	nlx_149135 +
Label	Neostriatum direct pathway spiny neuron +
Located in	Caudate nucleus +, Putamen +, and Nucleus accumbens +
LocationOfAxonArborization	Globus pallidus internal segment +, Globus pallidus external segment +, and Substantia nigra +
LocationOfLocalAxonArborization	Striosomal compartment of neostriatum +, and Matrix compartment of neostriatum +
ModifiedDate	2 July 2012 +
MolecularConstituents	Enkephalin +, and Substance P +
Neurotransmitter	GABA +
NeurotransmitterReceptors	D1 receptor +, AMPA-type glutamate-gated cationic channel +, and D2 receptor +
NumberOfPrimaryDendrites	3-5 +
OriginOfAxon	soma and sometimes dendrite +
Page has default formThis property is a special property in this wiki.	Petilla neuron +
Species	Mammal +
SpineDensityOnDendrites	Spiny high density +
SuperCategory	Neuron +
Synonym	Medium spiny neuron +, Neostriatal spiny neuron +, Medium-sized spiny neuron +, Striatal spiny neuron +, and Striatal medium spiny neuron +