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Neostriatum indirect pathway spiny neuron

Name: Neostriatum indirect pathway spiny neuron
Description: The principal projection neuron of the caudate and putamen.[1]
Synonym(s): Medium spiny neuron, Neostriatal spiny neuron, Medium-sized spiny neuron, Striatal spiny neuron, Striatal medium spiny neuron
Abbreviation: MSN
Has role: Principal neuron role
Super-category: Neuron
URL: Kemp and Powell,
*Id: nlx_149136
Organism: Mammal
Link to OWL / RDF: Download this content as OWL/RDF

Soma Specific Properties

Cell Soma Shape: Multipolar
Cell Soma Size: Medium soma
Soma Location: Caudate nucleus, Putamen, Nucleus accumbens

Dendrite Specific Properties

Spine density on dendrites: spiny high density

Axon Specific Properties

Axon myelination: myelinated
Axon projection laterality: ipsilateral
Origin of axon: soma and sometimes dendrite
Location of distant axon arborization: Globus pallidus internal segment, Globus pallidus external segment, Substantia nigra
Location of local axon arborization: Striosomal compartment of neostriatum, Matrix compartment of neostriatum

Intrinsic Properties

Neurotransmitter released: GABA
Neurotransmitter receptors: D1 receptor, AMPA-type glutamate-gated cationic channel, D2 receptor
Molecular constituents: Enkephalin, Substance P


  1. Wilson CJ & Groves PM (1980) Fine structure and synaptic connections of the common spiny neuron of the rat neostriatum: a study employing intracellular inject of horseradish peroxidase. J Comp Neurol 194: 599-615 PubMed


This page uses this default form:Petilla_neuron


Cwilson, Slarson, Yazin


*Note: Neurolex imports many terms and their ids from existing community ontologies, e.g., the Gene Ontology. Neurolex, however, is a dynamic site and any content beyond the identifier should not be presumed to reflect the content or views of the source ontology. Users should consult with the authoritative source for each ontology for current information.

Facts about Neostriatum indirect pathway spiny neuronRDF feed
AbbrevMSN  +
AxonMyelinationmyelinated  +
AxonProjectionLateralityipsilateral  +
CellSomaShapeCategory:Multipolar   +
CellSomaSizeMedium soma  +
CommentThis class is duplicated in NIF
CurationStatusuncurated  +
DefiningCitationKemp and Powell,  +
DefinitionThe principal projection neuron of the caudate and putamen.
DendriteThickness2-3 um  +
Has default formThis property is a special property in this wiki.Petilla neuron  +
Has rolePrincipal neuron role  +
Idnlx_149136  +
LabelNeostriatum indirect pathway spiny neuron  +
Located inCaudate nucleus  +, Putamen  +, and Nucleus accumbens  +
LocationOfAxonArborizationGlobus pallidus internal segment  +, Globus pallidus external segment  +, and Substantia nigra  +
LocationOfLocalAxonArborizationStriosomal compartment of neostriatum  +, and Matrix compartment of neostriatum  +
ModifiedDate2 July 2012  +
MolecularConstituentsEnkephalin  +, and Substance P  +
NeurotransmitterGABA  +
NeurotransmitterReceptorsD1 receptor  +, AMPA-type glutamate-gated cationic channel  +, and D2 receptor  +
NumberOfPrimaryDendrites3-5  +
OriginOfAxonsoma and sometimes dendrite  +
Page has default formThis property is a special property in this wiki.Petilla neuron  +
SpeciesMammal  +
SpineDensityOnDendritesSpiny high density  +
SuperCategoryNeuron  +
SynonymMedium spiny neuron  +, Neostriatal spiny neuron  +, Medium-sized spiny neuron  +, Striatal spiny neuron  +, and Striatal medium spiny neuron  +