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Neuronal acetylcholine receptor subunit beta-2
| Name: | Neuronal acetylcholine receptor subunit beta-2 |
| Description: | A protein that is a translation product of the CHRNB2 gene or a 1:1 ortholog thereof. Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This gene encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy. (Adapted from PRotein Ontoloty and Entrez Gene). |
| Synonym(s): | CHRNB2, EFNL3, nAChRB2, Cholinergic receptor, nicotinic, beta 2 |
| Is part of: | Cholinergic system |
| Related to: | Acetylcholine, Nicotine |
| Has role: | Acetylcholine Receptor, Neurotransmitter Receptor, Ion Channel |
| Abbreviation: | NACHRB2 |
| Super-category: | Protein |
| URL: | PRotein Ontology and Entrez Gene |
| Id: | PRO:000005463 |
| Link to OWL / RDF: | Download this content as OWL/RDF |
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| Abbrev | NACHRB2 + |
| CurationStatus | uncurated + |
| DefiningCitation | PRotein Ontology and Entrez Gene + |
| Definition | A protein that is a translation product of … A protein that is a translation product of the CHRNB2 gene or a 1:1 ortholog thereof. Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This gene encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy. (Adapted from PRotein Ontoloty and Entrez Gene). ed from PRotein Ontoloty and Entrez Gene). |
| Has role | Acetylcholine Receptor +, Neurotransmitter Receptor +, and Ion Channel + |
| Id | PRO:000005463 + |
| Is part of | Cholinergic system + |
| Label | Neuronal acetylcholine receptor subunit beta-2 + |
| ModifiedDate | 9 February 2010 + |
| RelatedTo | Acetylcholine +, and Nicotine + |
| SuperCategory | Protein + |
| Synonym | CHRNB2 +, EFNL3 +, nAChRB2 +, Cholinergic receptor +, nicotinic +, and beta 2 + |