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Nucleus paramedianus dorsalis

Name: Nucleus paramedianus dorsalis
Description: Small nucleus in the brainstem of human, located adjacent and medial to the nucleus prepositus in the dorsal medulla, described in several atlases of human brain stem. In transverse sections, it is oval with its long axis aligned with the dorsal border of the brainstem. It begins at about the same A-P level as the nucleus prepositus, just rostral to the hypoglossal nucleus. It includes calretinin immunoreactive large cells with oval or polygonal cell bodies. Cells are not immunoreactive for either calbindin or parvalbumin, but a few fibers immunoreactive to each protein are found within its central region. Cells in PMD are also immunoreactive to nNOS, and immunoreactivity to a neurofilament protein shows many labeled cells and fibers. According to Baizer et al., no equivalent structure was observed in the cat, rat, mouse or monkey atlas although they did not look at the brains of the great apes.[1]
Synonym(s): nucleus paramedianus dorsalis
Abbreviation: PMD
Is part of: medulla oblongata
Super-category: Regional part of brain
URL: Olszewski J, Baxter D. Cytoarchitecture of the human brain stem. Karger; Basel: 1954.
Id: nlx_143549
Publication link: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2078602/figure/F2/
Defining criteria: cyto-architecture, topography, chemoarchitecture
Organism: Human
Link to OWL / RDF: Download this content as OWL/RDF
Defining Criteria: cyto-architecture, topography, chemoarchitecture
Cyto-architecture defining Criteria: Cells in this region have large oval or polygonal cell bodies that stain darkly with a Nissl stain; distinguishable with AChE staining [1]
Topography defining Criteria: located adjacent and medial to the nucleus prepositus in the dorsal medulla; it begins at about the same A-P level as nucleus prepositus hypoglossi, just rostral to the hypoglossal nucleus
Chemoarchitecture defining Criteria: It contains calretinin immunoreactive large cells with oval or polygonal cell bodies. Cells are not immunoreactive for either calbindin or parvalbumin, but a few fibers immunoreactive to each protein are found within its central region. Cells in PMD are also immunoreactive to nNOS, and immunoreactivity to a neurofilament protein shows many labeled cells and fibers. The nucleus is much more prominent in sections processed for calretinin immunoreactivity compared to Nissl-stained sections. [1]
Overlaps : nucleus paramedianus dorsalis of OB1954; Sadjadpour and Brodal, 1968; Paxinos and Huang, 1995)


References

  1. 1.0 1.1 1.2 Baizer JS et al. (2007) Neurochemical organization of the nucleus paramedianus dorsalis in the human. Brain Res 1176: 45-52 PubMed

Notes

This page uses this default form:PONS_brain_region

Contributors

Ccdbuser, Memartone



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Facts about Nucleus paramedianus dorsalisRDF feed
AbbrevPMD  +
ChemoDefiningCriteriaIt contains calretinin immunoreactive larg It contains calretinin immunoreactive large cells with oval or polygonal cell bodies. Cells are not immunoreactive for either calbindin or parvalbumin, but a few fibers immunoreactive to each protein are found within its central region. Cells in PMD are also immunoreactive to nNOS, and immunoreactivity to a neurofilament protein shows many labeled cells and fibers. The nucleus is much more prominent in sections processed for calretinin immunoreactivity compared to Nissl-stained sections. tivity compared to Nissl-stained sections.
CurationStatusuncurated  +
CytoDefiningCriteriaCells in this region have large oval or polygonal cell bodies that stain darkly with a Nissl stain; distinguishable with AChE staining
DefiningCitationOlszewski J, Baxter D. Cytoarchitecture of the human brain stem. Karger; Basel: 1954.  +
DefiningCriteriacyto-architecture, topography, chemoarchitecture  +
DefinitionSmall nucleus in the brainstem of human, l Small nucleus in the brainstem of human, located adjacent and medial to the nucleus prepositus in the dorsal medulla, described in several atlases of human brain stem. In transverse sections, it is oval with its long axis aligned with the dorsal border of the brainstem. It begins at about the same A-P level as the nucleus prepositus, just rostral to the hypoglossal nucleus. It includes calretinin immunoreactive large cells with oval or polygonal cell bodies. Cells are not immunoreactive for either calbindin or parvalbumin, but a few fibers immunoreactive to each protein are found within its central region. Cells in PMD are also immunoreactive to nNOS, and immunoreactivity to a neurofilament protein shows many labeled cells and fibers. According to Baizer et al., no equivalent structure was observed in the cat, rat, mouse or monkey atlas although they did not look at the brains of the great apes. not look at the brains of the great apes.
Has default formThis property is a special property in this wiki.PONS brain region  +
Idnlx_143549  +
Is part ofMedulla oblongata  +
LabelNucleus paramedianus dorsalis  +
ModifiedDate2 August 2013  +
Page has default formThis property is a special property in this wiki.PONS brain region  +
PartiallyOverlapsWithNucleus paramedianus dorsalis of OB1954; Sadjadpour and Brodal  +, 1968; Paxinos and Huang  +, and 1995)  +
PublicationLinkhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC2078602/figure/F2/  +
SpeciesHuman  +
SuperCategoryRegional part of brain  +
Synonymnucleus paramedianus dorsalis  +
TomoDefiningCriterialocated adjacent and medial to the nucleus prepositus in the dorsal medulla; it begins at about the same A-P level as nucleus prepositus hypoglossi, just rostral to the hypoglossal nucleus