arrow

From NeuroLex

Jump to: navigation, search



Olfactory bulb (main) adult-born granule cell

Name: Olfactory bulb (main) adult-born granule cell
Description: The olfactory bulb adult-born granule cell is a cohort of cell that comprise a large fraction of the vertibrate olfactory bulb granule cell layer. These neurons proliferate from from the subventricular zone, migrate through the rostral migratory stream and integrate into the olfactory bulb granule cell layer. Upon arriving in the olfactory bulb granule cell layer they migrate radially outward and mature with morphologies similar to neonate olfactory bulb granule cells. This process continues throughout the adult life of the vertibrate. There is some decline in adult neurogenesis in aged vertebrates and the presence of the subventricular proliferative zone is controversial in humans[1]
Abbreviation: ABGC (MOB)
Has role: Intrinsic neuron role
Super-category: Neuron
*Id: nlx_144252
Organism: Vertebrata
Link to OWL / RDF: Download this content as OWL/RDF

Soma Specific Properties

Cell Soma Shape: Granule
Cell Soma Size: Small soma
Soma Location: Olfactory bulb main granule cell layer

Dendrite Specific Properties

Dendrite location: Dendrties arborize in the external plexiform layer where they contact the secondary/lateral dendrites of mitral cells via reciprocal dendrodendritic synapses. The basal dendrite remains restricted to the granule cell layer.
Spine density on dendrites: spiny high density[2]
Branching type: apical/basal

Axon Specific Properties

Origin of axon: no axon
Location of distant axon arborization: Anaxonic - no axon

Intrinsic Properties

Neurotransmitter released: GABA
Neurotransmitter receptors: AMPA-type glutamate-gated cationic channel, NMDA-type glutamate-gated cationic channel
Molecular constituents: parvalbumin

Categories related to Olfactory bulb (main) adult-born granule cell

Subventricular Zone


References

  1. Altman J (1969) Autoradiographic and histological studies of postnatal neurogenesis. IV. Cell proliferation and migration in the anterior forebrain, with special reference to persisting neurogenesis in the olfactory bulb. J Comp Neurol 137: 433-57 PubMed
  2. Dahlen JE et al. (2011) Morphological analysis of activity-reduced adult-born neurons in the mouse olfactory bulb. Front Neurosci 5: 66 PubMed

Notes

This page uses this default form:Petilla_neuron

Contributors

Cgreer, Jeffdahlen, Memartone



bookmark

*Note: Neurolex imports many terms and their ids from existing community ontologies, e.g., the Gene Ontology. Neurolex, however, is a dynamic site and any content beyond the identifier should not be presumed to reflect the content or views of the source ontology. Users should consult with the authoritative source for each ontology for current information.

Facts about Olfactory bulb (main) adult-born granule cellRDF feed
AbbrevABGC (MOB)  +
BranchingMetricsapical/basal  +
CellSomaShapeCategory:Granule   +
CellSomaSizeSmall soma  +
CurationStatusgraph position temporary  +
CuratorMaryann Martone  +
DefinitionThe olfactory bulb adult-born granule cell The olfactory bulb adult-born granule cell is a cohort of cell that comprise a large fraction of the vertibrate olfactory bulb granule cell layer. These neurons proliferate from from the subventricular zone, migrate through the rostral migratory stream and integrate into the olfactory bulb granule cell layer. Upon arriving in the olfactory bulb granule cell layer they migrate radially outward and mature with morphologies similar to neonate olfactory bulb granule cells. This process continues throughout the adult life of the vertibrate. There is some decline in adult neurogenesis in aged vertebrates and the presence of the subventricular proliferative zone is controversial in humans liferative zone is controversial in humans
DendriteLocationDendrties arborize in the external plexiform layer where they contact the secondary/lateral dendrites of mitral cells via reciprocal dendrodendritic synapses. The basal dendrite remains restricted to the granule cell layer.  +
EditorialNoteI'm wondering whether this is a subcategoy of olfactory bulb (main) granule cell or whether these represent a distinct class. Needs review
Has default formThis property is a special property in this wiki.Petilla neuron  +
Has roleIntrinsic neuron role  +
Idnlx_144252  +
LabelOlfactory bulb (main) adult-born granule cell  +
Located inOlfactory bulb main granule cell layer  +
LocationOfAxonArborizationAnaxonic - no axon  +
ModifiedDate1 May 2013  +
MolecularConstituentsParvalbumin  +
NeurotransmitterGABA  +
NeurotransmitterReceptorsAMPA-type glutamate-gated cationic channel  +, and NMDA-type glutamate-gated cationic channel  +
OriginOfAxonno axon  +
Page has default formThis property is a special property in this wiki.Petilla neuron  +
SpeciesVertebrata  +
SpineDensityOnDendritesSpiny high density  +
SuperCategoryNeuron  +