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Olfactory bulb (main) mitral cell

Name: Olfactory bulb (main) mitral cell
Description: Principal neuron located in the olfactory bulb in the mammalian central nervous system. The cell bodies are arranged in a thin layer between the granule cell layer and the external plexiform layer. Each mitral cell is usually characterized in the mammal by a single primary dendrite that traverses the external plexiform layer and terminates within an olfactory glomerulus in a tuft of branches which receives input from the axons of olfactory receptor neurons. Axons of the mitral cells project to a number of areas in the brain, including the piriform cortex, entorhinal cortex, olfactory tubercle, and amygdala.
Synonym(s): Mitral neuron
Abbreviation: MC
Has role: Principal neuron role
Super-category: Neuron
URL: Shepherd, Chen and Greer (2004). Olfactory bulb. In The Synaptic Organization of the Brain, ed 5. New York: Oxford University Press.
*Id: nifext_120
Defining criteria: Morphology; Connectivity; Biochemical
Organism: Mammal
Link to OWL / RDF: Download this content as OWL/RDF

Soma Specific Properties

Cell Soma Shape: Mitral
Cell Soma Size: Large soma
Soma Location: Olfactory bulb main mitral cell body layer

Dendrite Specific Properties

Spine density on dendrites: Smooth

Axon Specific Properties

Axon myelination: myelinated
Axon projection laterality: ipsilateral
Origin of axon: soma and sometimes dendrite
Location of distant axon arborization: olfactory cortex
Location of local axon arborization: Olfactory bulb main granule cell layer, Olfactory bulb main external plexiform layer

Intrinsic Properties

Neurotransmitter released: Glutamate
Neurotransmitter receptors: GABA_Receptor, AMPA-type glutamate-gated cationic channel, NMDA, GABA A-gated anionic channel, GABA-B Receptor
Molecular constituents: T-box protein 21, Protocadherin gamma-C3
Defining Criteria: Morphology; Connectivity; Biochemical


SenseLab URL: http://senselab.med.yale.edu/NeuronDB/NeuronProp.aspx?id=267

Notes

This page uses this default form:Petilla_neuron



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*Note: Neurolex imports many terms and their ids from existing community ontologies, e.g., the Gene Ontology. Neurolex, however, is a dynamic site and any content beyond the identifier should not be presumed to reflect the content or views of the source ontology. Users should consult with the authoritative source for each ontology for current information.

Facts about Olfactory bulb (main) mitral cellRDF feed
AbbrevMC  +
AxonDiameterRat: 1 um  +
AxonLengthseveral mm  +
AxonMyelinationmyelinated  +
AxonProjectionLateralityipsilateral  +
CellSomaShapeCategory:Mitral   +
CellSomaSizeLarge soma  +
CellularSynapticTargetOlfactory bulb (main) granule cell  +, Intrinsic: granule cells in granule cell layer and external plexiform layer; possibly Blanes cells in granule cell layer; Extrinsic  +, and Pyramidal cells of olfactory cortex; superficial interneurons of olfactory cortex  +
Created5 September 2007  +
CurationStatusgraph position temporary  +
DefiningCitationShepherd, Chen and Greer (2004). Olfactory bulb. In The Synaptic Organization of the Brain, ed 5. New York: Oxford University Press.  +
DefiningCriteriaMorphology; Connectivity; Biochemical  +
DefinitionPrincipal neuron located in the olfactory Principal neuron located in the olfactory bulb in the mammalian central nervous system. The cell bodies are arranged in a thin layer between the granule cell layer and the external plexiform layer. Each mitral cell is usually characterized in the mammal by a single primary dendrite that traverses the external plexiform layer and terminates within an olfactory glomerulus in a tuft of branches which receives input from the axons of olfactory receptor neurons. Axons of the mitral cells project to a number of areas in the brain, including the piriform cortex, entorhinal cortex, olfactory tubercle, and amygdala. cortex, olfactory tubercle, and amygdala.
DendriteLengthRat: Apical trunk: 400-500 um; apical tuft: 70-150 um; basal: up to 1 mm  +
DendriteThicknessRat: Apical trunk: 2-6; apical tuft: 1-2 um at origin; basal: 2-3 um at origin, narrowing through branching to less than 1 um.  +
EditorialNotehttp://senselab.med.yale.edu/neurondb/Neur http://senselab.med.yale.edu/neurondb/NeuronProp.aspx?id=267 I changed protocadherin-2 to Protocadherin gamma-C3, as that seems to be the preferred name in NCBI and the Protein Ontology. Changed TBX-21 to T-box protein 21, to distinguish it from the gene. Please let me know if these changes aren't appropriate. know if these changes aren't appropriate.
ExampleImageOlfactory bulb (main) mitral cell.gif  +
FiringPatternsRegular firing and bursting  +
Has default formThis property is a special property in this wiki.Petilla neuron  +
Has rolePrincipal neuron role  +
Idnifext_120  +
LabelOlfactory bulb (main) mitral cell  +
Located inOlfactory bulb main mitral cell body layer  +
LocationOfAxonArborizationOlfactory cortex  +
LocationOfLocalAxonArborizationOlfactory bulb main granule cell layer  +, and Olfactory bulb main external plexiform layer  +
ModifiedDate28 August 2014  +
MolecularConstituentsT-box protein 21  +, and Protocadherin gamma-C3  +
NeurotransmitterGlutamate  +
NeurotransmitterReceptorsGABA receptor  +, AMPA-type glutamate-gated cationic channel  +, NMDA  +, GABA A-gated anionic channel  +, and GABA-B Receptor  +
NumberOfPrimaryDendrites1 (applies to most mammals)  +
OriginOfAxonsoma and sometimes dendrite  +
Page has default formThis property is a special property in this wiki.Petilla neuron  +
PassiveSubthresholdParametersRN, 20=50 megohm  +
SpeciesMammal  +
SpikingFeaturessame  +
SpineDensityOnDendritesSmooth  +
SpontaneousFiringPatternsRegular firing and bursting  +
SpontaneousFiringRatemedium firing  +
SubcellularSynapticTargetIntrinsic: Dendrodendritic synapses on granule cell dendritic spines. Extrinsic: Axon in olfactory cortical areas on apical dendritic spines of pyramidal cells and dendrites of superficial interneurons  +
SuperCategoryNeuron  +
SynapticPhysiologyOutput synapses at both dendrodendritic and axodendritic synapses: GLU NMDA, AMPA; input synapses: GABA from granule cell dendrodendritic synapses  +
SynonymMitral neuron  +