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Oxyphenonium

Name: Oxyphenonium
Description: A quaternary ammonium anticholinergic agent with peripheral side effects similar to those of atropine. It is used as an adjunct in the treatment of gastric and duodenal ulcer, and to relieve visceral spasms. The drug has also been used in the form of eye drops for mydriatic effect. (PubChem) Pharmacology: Oxyphenonium is an anticholinergic drug, a medication that reduces the effect of acetylcholine, a chemical released from nerves that stimulates muscles, by blocking the receptors for acetylcholine on smooth muscle (a type of muscle). It also has a direct relaxing effect on smooth muscle. Oxyphenonium is used to treat or prevent spasm in the muscles of the gastrointestinal tract in the irritable bowel syndrome. In addition, Oxyphenonium inhibits gastrointestinal propulsive motility and decreases gastric acid secretion and controls excessive pharyngeal, tracheal and bronchial secretions. Mechanism of action: Action is achieved via a dual mechanism: (1) a specific anticholinergic effect (antimuscarinic) at the acetylcholine-receptor sites and (2) a direct effect upon smooth muscle (musculotropic). Drug type: Approved. Small Molecule. Drug category: Muscarinic Antagonists. Mydriatics. Parasympatholytics
Synonym(s): DCF, Hydroxymethylgramicidin, Methocidin (Dcf:Inn), Methocidine (INN-French), Methocidinum (INN-Latin), Metocidina (INN-Spanish), Oxiphenonum, Oxyphenonium Bromide, Antrenyl, Argicillin, Methacin, Methocidin
Has role: Drug
Super-category: Molecular entity
URL: http://www.drugbank.ca/drugs/DB00219
*Id: DB00219
Related to: Cholinergic system, Muscarinic acetylcholine receptor M1
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Ayeliset, Ccdbuser, Nifbot2



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Facts about OxyphenoniumRDF feed
Commenttaken from DrugBank
CurationStatusuncurated  +
CuratorAb  +
DefiningCitationhttp://www.drugbank.ca/drugs/DB00219  +
DefinitionA quaternary ammonium anticholinergic agen A quaternary ammonium anticholinergic agent with peripheral side effects similar to those of atropine. It is used as an adjunct in the treatment of gastric and duodenal ulcer, and to relieve visceral spasms. The drug has also been used in the form of eye drops for mydriatic effect. (PubChem) Pharmacology: Oxyphenonium is an anticholinergic drug, a medication that reduces the effect of acetylcholine, a chemical released from nerves that stimulates muscles, by blocking the receptors for acetylcholine on smooth muscle (a type of muscle). It also has a direct relaxing effect on smooth muscle. Oxyphenonium is used to treat or prevent spasm in the muscles of the gastrointestinal tract in the irritable bowel syndrome. In addition, Oxyphenonium inhibits gastrointestinal propulsive motility and decreases gastric acid secretion and controls excessive pharyngeal, tracheal and bronchial secretions. Mechanism of action: Action is achieved via a dual mechanism: (1) a specific anticholinergic effect (antimuscarinic) at the acetylcholine-receptor sites and (2) a direct effect upon smooth muscle (musculotropic). Drug type: Approved. Small Molecule. Drug category: Muscarinic Antagonists. Mydriatics. Parasympatholytics ntagonists. Mydriatics. Parasympatholytics
Has roleDrug  +
IdDB00219  +
LabelOxyphenonium  +
ModifiedDate14 April 2014  +
RelatedToCholinergic system  +, and Muscarinic acetylcholine receptor M1  +
SuperCategoryMolecular entity  +
SynonymDCF  +, Hydroxymethylgramicidin  +, Methocidin (Dcf:Inn)  +, Methocidine (INN-French)  +, Methocidinum (INN-Latin)  +, Metocidina (INN-Spanish)  +, Oxiphenonum  +, Oxyphenonium Bromide  +, Antrenyl  +, Argicillin  +, Methacin  +, and Methocidin  +