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Oxytocin
| Name: | Oxytocin |
| Description: | Synthetic 9 residue cyclic peptide. The hormone is prepared synthetically to avoid possible contamination with vasopressin (ADH) and other small polypeptides with biologic activity. Pharmacology: Used to induce labor or to enhance uterine contractions during labor. Uterine motility depends on the formation of the contractile protein actomyosin under the influence of the Ca2+-dependent phosphorylating enzyme myosin light-chain kinase. Oxytocin promotes contractions by increasing the intracellular Ca2+, which in turn activates myosins light chain kinase.. Oxytocin has specific receptors in the muscle llining of the uterus and the receptor concentration increases greatly during pregnancy, reaching a maximum in early labor at term. Mechanism of action: Binds the oxytocin receptor which leads to an increase in intracellular calcium levels. Drug type: Approved. Biotech. Drug category: Anti-tocolytic Agents. Labor Induction Agents. Oxytocics |
| Synonym(s): | Pitocin, Syntocinon, Oxytocin (BAM Biotech), Pitocin (Parke-Davis), Syntocinon (Sandoz) |
| Related to: | Oxytocin-neurophysin 1, Prolyl endopeptidase |
| Has role: | Drug, Neuropeptide |
| Super-category: | Peptide |
| URL: | http://www.drugbank.ca/drugs/DB00107 |
| Id: | CHEBI: 7872 |
| Link to OWL / RDF: | Download this content as OWL/RDF |
Neurons that have Oxytocin as their neurotransmitter
Facts about OxytocinRDF feed
| Comment | taken from DrugBank |
| CurationStatus | uncurated + |
| Curator | Ab + |
| DefiningCitation | http://www.drugbank.ca/drugs/DB00107 + |
| Definition | Synthetic 9 residue cyclic peptide. The ho … Synthetic 9 residue cyclic peptide. The hormone is prepared synthetically to avoid possible contamination with vasopressin (ADH) and other small polypeptides with biologic activity. Pharmacology: Used to induce labor or to enhance uterine contractions during labor. Uterine motility depends on the formation of the contractile protein actomyosin under the influence of the Ca2+-dependent phosphorylating enzyme myosin light-chain kinase. Oxytocin promotes contractions by increasing the intracellular Ca2+, which in turn activates myosins light chain kinase.. Oxytocin has specific receptors in the muscle llining of the uterus and the receptor concentration increases greatly during pregnancy, reaching a maximum in early labor at term. Mechanism of action: Binds the oxytocin receptor which leads to an increase in intracellular calcium levels. Drug type: Approved. Biotech. Drug category: Anti-tocolytic Agents. Labor Induction Agents. Oxytocics Agents. Labor Induction Agents. Oxytocics |
| Has role | Drug +, and Neuropeptide + |
| Id | CHEBI: 7872 + |
| Label | Oxytocin + |
| ModifiedDate | 16 March 2010 + |
| RelatedTo | Oxytocin-neurophysin 1 +, and Prolyl endopeptidase + |
| SuperCategory | Peptide + |
| Synonym | Pitocin +, Syntocinon +, Oxytocin (BAM Biotech) +, Pitocin (Parke-Davis) +, and Syntocinon (Sandoz) + |