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Parkinsons disease
| Name: | Parkinsons disease |
| Description: | * A disease characterized as a progressive motor disability manifested by tremors, shaking, muscular rigidity, and lack of postural reflexes. (PSY) * A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75) (MSH) * progressive, degenerative disorder of the nervous system characterized by tremors, rigidity, bradykinesia, postural instability, and gait abnormalities; caused by a loss of neurons and a decrease of dopamine in the basal ganglia. (CSP) |
| Synonym(s): | Idiopathic PD, Parkinsonian disorder, Parkinson syndrome, Paralysis Agitans, Parkinson, Parkinson's disease, Parkinsons, Parkinson's, Parkinson disease, Parkinson's syndrome |
| Abbreviation: | PD |
| Super-category: | Neurodegenerative disease |
| Id: | birnlex_2098 |
| Link to OWL / RDF: | Download this content as OWL/RDF |
Categories related to Parkinsons disease
D2 receptor, Dopamine receptor, Hoehn and Yahr scale, Lewy Body, Unified Parkinsons disease rating scale
- Definition Source: http://purl.org/nbirn/birnlex/ontology/annotation/OBO_annotation_properties.owl#UMLS
Facts about Parkinsons diseaseRDF feed
| Abbrev | PD + |
| Created | 5 March 2007 + |
| CurationStatus | uncurated + |
| Curator | Bill Bug + |
| Definition | * A disease characterized as a progressive … * A disease characterized as a progressive motor disability manifested by tremors, shaking, muscular rigidity, and lack of postural reflexes. (PSY) * A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75) (MSH) * progressive, degenerative disorder of the nervous system characterized by tremors, rigidity, bradykinesia, postural instability, and gait abnormalities; caused by a loss of neurons and a decrease of dopamine in the basal ganglia. (CSP) se of dopamine in the basal ganglia. (CSP) |
| DefinitionSource | Http://purl.org/nbirn/birnlex/ontology/annotation/OBO annotation properties.owl + |
| Id | birnlex_2098 + |
| Label | Parkinsons disease + |
| ModifiedDate | 4 May 2010 + |
| SuperCategory | Neurodegenerative disease + |
| Synonym | Idiopathic PD +, Parkinsonian disorder +, Parkinson syndrome +, Paralysis Agitans +, Parkinson +, Parkinson's disease +, Parkinsons +, Parkinson's +, Parkinson disease +, and Parkinson's syndrome + |
| Umlscui | C0030567 + |