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Parkinsons disease

Name: Parkinsons disease
Description: * A disease characterized as a progressive motor disability manifested by tremors, shaking, muscular rigidity, and lack of postural reflexes. (PSY) * A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75) (MSH) * progressive, degenerative disorder of the nervous system characterized by tremors, rigidity, bradykinesia, postural instability, and gait abnormalities; caused by a loss of neurons and a decrease of dopamine in the basal ganglia. (CSP)
Synonym(s): Idiopathic PD, Parkinsonian disorder, Parkinson syndrome, Paralysis Agitans, Parkinson, Parkinson's disease, Parkinsons, Parkinson's, Parkinson disease, Parkinson's syndrome
Abbreviation: PD
Super-category: Neurodegenerative disease
*Id: birnlex_2098
Alternate Id(s): ModelDB:65417
Link to OWL / RDF: Download this content as OWL/RDF

Categories related to Parkinsons disease

D2 receptor, Deep brain stimulation, Dopamine receptor, Hoehn and Yahr scale, Lewy Body, Unified Parkinsons disease rating scale




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*Note: Neurolex imports many terms and their ids from existing community ontologies, e.g., the Gene Ontology. Neurolex, however, is a dynamic site and any content beyond the identifier should not be presumed to reflect the content or views of the source ontology. Users should consult with the authoritative source for each ontology for current information.

Facts about Parkinsons diseaseRDF feed
AbbrevPD  +
Created5 March 2007  +
CurationStatusuncurated  +
CuratorBill Bug  +
Definition* A disease characterized as a progressive * A disease characterized as a progressive motor disability manifested by tremors, shaking, muscular rigidity, and lack of postural reflexes. (PSY) * A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75) (MSH) * progressive, degenerative disorder of the nervous system characterized by tremors, rigidity, bradykinesia, postural instability, and gait abnormalities; caused by a loss of neurons and a decrease of dopamine in the basal ganglia. (CSP) se of dopamine in the basal ganglia. (CSP)
DefinitionSourceHttp://purl.org/nbirn/birnlex/ontology/annotation/OBO annotation properties.owl  +
Idbirnlex_2098  +
LabelParkinsons disease  +
ModifiedDate30 July 2014  +
SuperCategoryNeurodegenerative disease  +
SynonymIdiopathic PD  +, Parkinsonian disorder  +, Parkinson syndrome  +, Paralysis Agitans  +, Parkinson  +, Parkinson's disease  +, Parkinsons  +, Parkinson's  +, Parkinson disease  +, and Parkinson's syndrome  +
UmlscuiC0030567  +
XrefModelDB:65417  +