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Resource:Adenylate Uridylate-rich-Rich Element-Containing mRNA Database

Name: Resource:Adenylate Uridylate-rich-Rich Element-Containing mRNA Database
Description:

ARED (Adenylate Uridylate-Rich Element-mRNA database) contains the complete entries of human ARE-containing full-length mRNAs.

ARED is further clustered into five groups depending on the number of motifs in the ARE stretch. Groups 1-4 contain five, four, three and two pentameric (AUUUA) repeats, respectively, while Group 5 contains only one repeat within the 13-bp pattern. Clustering was performed in such a way that, for example, Group 1 included not only exact five or more continuous ARE pentamers but also those with 10% ambiguity, so that a stretch of NUUUAUUUAUUUAUUUAUUUN would fall in this category. This process was verified by a phylogenic tree relationship using Clustal-W alignment of ARE stretches and their variations. As could be expected, this analysis showed that the lower the number of ARE motifs in a group, the higher the number of sequences that were included, and apparently the more functionally diverse the corresponding ARE-genes.
Other Name(s): ARED
Parent Organization: King Faisal Specialist Hospital & Research Center, The Biomolecular Research Program
Resource Type(s): Database
Keywords: adenylate uridylate-rich element-mrna, are-gene, human mrna, rna sequence database
Resource: Resource
URL: http://brp.kfshrc.edu.sa/ARED
Id: nif-0000-02566
Link to OWL / RDF: Download this content as OWL/RDF

Curation status: Uncurated

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Facts about Resource:Adenylate Uridylate-rich-Rich Element-Containing mRNA DatabaseRDF feed
CurationStatuscurated  +
DefiningCitationhttp://brp.kfshrc.edu.sa/ARED  +
Definition

ARED (Adenylate Uridylate-Rich Ele
ARED (Adenylate Uridylate-Rich Element-mRNA database) contains the complete entries of human ARE-containing full-length mRNAs.

ARED is further clustered into five groups depending on the number of motifs in the ARE stretch. Groups 1-4 contain five, four, three and two pentameric (AUUUA) repeats, respectively, while Group 5 contains only one repeat within the 13-bp pattern. Clustering was performed in such a way that, for example, Group 1 included not only exact five or more continuous ARE pentamers but also those with 10% ambiguity, so that a stretch of NUUUAUUUAUUUAUUUAUUUN would fall in this category. This process was verified by a phylogenic tree relationship using Clustal-W alignment of ARE stretches and their variations. As could be expected, this analysis showed that the lower the number of ARE motifs in a group, the higher the number of sequences that were included, and apparently the more functionally diverse the corresponding ARE-genes.
diverse the corresponding ARE-genes.
Has default formThis property is a special property in this wiki.Resource  +
Has roleDatabase  +
Idnif-0000-02566  +
Is part ofKing Faisal Specialist Hospital & Research Center  +, and The Biomolecular Research Program  +
KeywordsAdenylate uridylate-rich element-mrna  +, Are-gene  +, Human mrna  +, and Rna sequence database  +
LabelResource:Adenylate Uridylate-rich-Rich Element-Containing mRNA Database  +
ModifiedDate20 June 2013  +
Page has default formThis property is a special property in this wiki.Resource  +
SuperCategoryResource  +
SynonymARED  +