This freely accessible online resource allows for simultaneous navigation and comparison of different mouse brains at high resolution, providing users with a dataset to probe for possible differences in gene regulation.

For both the strain and sex components of the project, a panel of 49 well known drug target genes that are expressed in the adult and developing brain and encompass sites of action for FDA-approved drugs were assayed. These include genes encoding proteins involved in the synthesis, transport and signaling of neurotransmitters, G protein-coupled receptors and ion channels, as well as other intracellular signaling molecules. In addition to holding clinical relevance, the diversity of genes selected allows for the identification of possible trends that might emerge by gene class or family between strains or sex.