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Resource:Alternate Splicing - induced ALteration of Protein Structure

Name: Resource:Alternate Splicing - induced ALteration of Protein Structure
Description:

This database, AS-ALPS (Alternative Splicing-induced ALteration of Protein Structure), is aimed at providing useful information to analyze effect of AS on protein interaction and network through alteration of protein structure.
In AS-ALPS, regions of amino acid sequences changed by AS ("AS regions") which are detected in human and mouse transcript sequences in H-InvDB, FANTOM and RefSeq, are linked to information extracted from PDB about residues forming hydrophobic cores and inter-molecular interaction sites. This makes it possible to directly infer whether protein structure and/or interaction are affected by each AS event. In addition, AS-ALPS provides links to a protein network database KEGG, making it easy to know which network and which node in the network can be influenced by AS.

Sponsors: This database was supported by a grant of the Genome Network Project from Ministry of Education, Culture, Sports, Science and Technology of Japan.

Other Name(s): AS-ALPS
Parent Organization: National Institute of Genetics, Japan
Resource Type(s): database
Resource: Resource
URL: http://as-alps.nagahama-i-bio.ac.jp
Id: nif-0000-02570
Keywords: alternative splicing, amino acid sequence, inter-molecular interaction, protein, protein network, protein structure
Link to OWL / RDF: Download this content as OWL/RDF

Curation status: Curated

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Contributors

Aarnaud, Ccdbuser, Eddy kim, Nifbot2



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Facts about Resource:Alternate Splicing - induced ALteration of Protein StructureRDF feed
CurationStatuscurated  +
DefiningCitationhttp://as-alps.nagahama-i-bio.ac.jp  +
Definition

This database, AS-ALPS (Alternativ
This database, AS-ALPS (Alternative Splicing-induced ALteration of Protein Structure), is aimed at providing useful information to analyze effect of AS on protein interaction and network through alteration of protein structure.
In AS-ALPS, regions of amino acid sequences changed by AS ("AS regions") which are detected in human and mouse transcript sequences in H-InvDB, FANTOM and RefSeq, are linked to information extracted from PDB about residues forming hydrophobic cores and inter-molecular interaction sites. This makes it possible to directly infer whether protein structure and/or interaction are affected by each AS event. In addition, AS-ALPS provides links to a protein network database KEGG, making it easy to know which network and which node in the network can be influenced by AS.

Sponsors: This database was supported by a grant of the Genome Network Project from Ministry of Education, Culture, Sports, Science and Technology of Japan.

ce and Technology of Japan.

Has default formThis property is a special property in this wiki.Resource  +
Has roleDatabase  +
Idnif-0000-02570  +
Is part ofNational Institute of Genetics  +, and Japan  +
KeywordsAlternative splicing  +, Amino acid sequence  +, Inter-molecular interaction  +, Protein  +, Protein network  +, and Protein structure  +
LabelResource:Alternate Splicing - induced ALteration of Protein Structure  +
ModifiedDate13 October 2010  +
SuperCategoryResource  +
SynonymAS-ALPS  +