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Resource:BayGenomics

Name: Resource:BayGenomics
Description:

The BayGenomics gene-trap resource provides researchers with access to thousands of mouse embryonic stem (ES) cell lines harboring characterized insertional mutations in both known and novel genes. The major goal of BayGenomics is to identify genes relevant to cardiovascular and pulmonary disease.
BayGenomics aims to use gene-trap techniques in embryonic stem (ES) cells to inactivate 2,500 random genes per year and to use bioinformatics and gene-expression studies to gain insights into the possible importance of new genes for cardiopulmonary development and cardiopulmonary diseases. Lastly, it aims to produce knockout mice of interest to the cardiopulmonary research community from a subset of gene-trapped ES cell clones.
The BayGenomics project is organized into nine components involving three institutions: The J. David Gladstone Institute for Cardiovascular Disease, the University of California, San Francisco (UCSF), and the University of California at Berkeley (UCB). Each component of this Program for Genomic Applications (PGA) is making major contributions to the National Heart, Lung, and Blood Institute's (NHLBI) genomics program and help to decipher new genes that are important for cardiopulmonary disease and development.
To date, BayGenomics have trapped hundreds of mouse genes, many corresponding to novel genes or expressed sequence tags (ESTs). Many of these insertional mutants have already been transmitted through the germline. Many research labs have had success in generating knockout mice from the library of ES cell mutants.
Categories: Gene-, System-, or Disease- Specific Databases

basic research knowledge base
Other Name(s): BayGenomics
Parent Organization: University of California at San Francisco; California; USA
Resource Type(s): tissue bank, organism repository
Resource: Resource
URL: http://baygenomics.ucsf.edu/
*Id: nif-0000-21042
Keywords: embryonic, expression, gene, basic research knowledge base, bioinformatic, cardiopulmonary, cardiovascular, cell, clone, disease, genomic, germline, insertional, line, mouse, mutant, mutation, pulmonary, stem
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Facts about Resource:BayGenomicsRDF feed
CurationStatusuncurated  +
DefiningCitationhttp://baygenomics.ucsf.edu/  +
Definition

The BayGenomics gene-trap resource
The BayGenomics gene-trap resource provides researchers with access to thousands of mouse embryonic stem (ES) cell lines harboring characterized insertional mutations in both known and novel genes. The major goal of BayGenomics is to identify genes relevant to cardiovascular and pulmonary disease.
BayGenomics aims to use gene-trap techniques in embryonic stem (ES) cells to inactivate 2,500 random genes per year and to use bioinformatics and gene-expression studies to gain insights into the possible importance of new genes for cardiopulmonary development and cardiopulmonary diseases. Lastly, it aims to produce knockout mice of interest to the cardiopulmonary research community from a subset of gene-trapped ES cell clones.
The BayGenomics project is organized into nine components involving three institutions: The J. David Gladstone Institute for Cardiovascular Disease, the University of California, San Francisco (UCSF), and the University of California at Berkeley (UCB). Each component of this Program for Genomic Applications (PGA) is making major contributions to the National Heart, Lung, and Blood Institute's (NHLBI) genomics program and help to decipher new genes that are important for cardiopulmonary disease and development.
To date, BayGenomics have trapped hundreds of mouse genes, many corresponding to novel genes or expressed sequence tags (ESTs). Many of these insertional mutants have already been transmitted through the germline. Many research labs have had success in generating knockout mice from the library of ES cell mutants.
Categories: Gene-, System-, or Disease- Specific Databases
basic research knowledge base
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basic research knowledge base
Has default formThis property is a special property in this wiki.Resource  +
Has roleTissue bank  +, and Organism repository  +
Idnif-0000-21042  +
Is part ofUniversity of California at San Francisco; California; USA  +
KeywordsEmbryonic  +, Expression  +, Gene  +, Basic research knowledge base  +, Bioinformatic  +, Cardiopulmonary  +, Cardiovascular  +, Cell  +, Clone  +, Disease  +, Genomic  +, Germline  +, Insertional  +, Line  +, Mouse  +, Mutant  +, Mutation  +, Pulmonary  +, and Stem  +
LabelResource:BayGenomics  +
ModifiedDate29 March 2011  +
SuperCategoryResource  +
SynonymBayGenomics  +