The BayGenomics gene-trap resource provides researchers with access to thousands of mouse embryonic stem (ES) cell lines harboring characterized insertional mutations in both known and novel genes. The major goal of BayGenomics is to identify genes relevant to cardiovascular and pulmonary disease.
|Parent Organization:||University of California at San Francisco; California; USA|
|Resource Type(s):||tissue bank, organism repository|
|Keywords:||embryonic, expression, gene, basic research knowledge base, bioinformatic, cardiopulmonary, cardiovascular, cell, clone, disease, genomic, germline, insertional, line, mouse, mutant, mutation, pulmonary, stem|
|Link to OWL / RDF:||Download this content as OWL/RDF|
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The BayGenomics gene-trap resource …
BayGenomics aims to use gene-trap techniques in embryonic stem (ES) cells to inactivate 2,500 random genes per year and to use bioinformatics and gene-expression studies to gain insights into the possible importance of new genes for cardiopulmonary development and cardiopulmonary diseases. Lastly, it aims to produce knockout mice of interest to the cardiopulmonary research community from a subset of gene-trapped ES cell clones.
The BayGenomics project is organized into nine components involving three institutions: The J. David Gladstone Institute for Cardiovascular Disease, the University of California, San Francisco (UCSF), and the University of California at Berkeley (UCB). Each component of this Program for Genomic Applications (PGA) is making major contributions to the National Heart, Lung, and Blood Institute's (NHLBI) genomics program and help to decipher new genes that are important for cardiopulmonary disease and development.
from the library of ES cell mutants.
|Has default formThis property is a special property in this wiki.||Resource +|
|Has role||Tissue bank +, and Organism supplier +|
|Is part of||University of California at San Francisco; California; USA +|
|Keywords||Embryonic +, Expression +, Gene +, Bioinformatic +, Cardiopulmonary +, Cell +, Clone +, Disease +, Genomic +, Germline +, Insertional +, Line +, Mouse +, Mutant +, Mutation +, Pulmonary +, Stem +, Cardiovascular +, and Pulmonary disease +|
|ModifiedDate||27 July 2012 +|
|Page has default formThis property is a special property in this wiki.||Resource +|
|RelatedTo||Resource:One Mind Biospecimen Bank Listing +, and US Biobank +|