The BMRB archive consists of four main data depositories: (i) quantitative NMR spectral parameters for proteins, peptides, nucleic acids, carbohydrates and ligands or cofactors and derived data (relaxation parameters, residual dipolar couplings, hydrogen exchange rates, pK(a) values, etc.), (ii) databases for NMR restraints processed from original author depositions available from the Protein Data Bank, (iii) time-domain spectral data from NMR experiments used to assign spectral resonances and determine the structures of biological macromolecules and (iv) a database of one- and two-dimensional (1)H and (13)C one- and two-dimensional NMR spectra for over 250 metabolites. The BMRB website provides free access to all of these data. BMRB has tools for querying the archive and retrieving information and an ftp site where data in the archive can be downloaded in bulk.

BMRB will accept: quantitative NMR data for a peptide, protein, nucleic acid, or polysaccharide and their ligands and cofactors assigned on an atom-specific basis, and data derived from the analysis of such data. Submitted data are to be in valid NMR-STAR format; they may be created by tools that output data in this format. The types of NMR data that can be included in a deposition and the mandatory supporting information accompanying a deposition are reviewed yearly by the BMRB Advisory Board.

BMRB data is listed by:

• Macromolecular types
  
• NMR spectral parameters
  
• Kinetics
  
• Thermodynamics
  
• Restraints
  
• Small molecule structures
• Time-domain sets
  
• Solid-state NMR
• Unfolded proteins
• Binding Data
• Diseases
• NMR data combined with coordinates and restraints