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Resource:BrainSpan: Atlas of the Developing Human Brain

Name: Resource:BrainSpan: Atlas of the Developing Human Brain
Description: An atlas of the developing human brain designed as a foundational resource for studying transcriptional mechanisms involved in human brain development. The atlas consists of a variety of data modalities and data mining tools.

Developmental Transcriptome: RNA sequencing and exon microarray data profiling up to sixteen cortical and subcortical structures across the full course of human brain development.

Prenatal LMD Microarray: High-resolution neuroanatomical transcriptional profiles of ~300 distinct structures spanning the entire brain for four midgestional prenatal specimens.

In Situ Hybridization (ISH): High-resolution in situ hybridization image data covering selected genes and brain regions in developing and adult human brain.

Reference Atlas: Full color, high-resolution anatomic reference atlases of prenatal (two stages) and adult human brain along with supporting histology, magnetic resonance imaging (MRI) and diffusion weighted imaging (DWI) data.

The NIF Data Federation currently indexes the 4 Developmental Transcriptome BrainSpan datasets: RNA-Seq exons, RNA-Seq exons summarized to genes, Exon microarray summarized to probe sets, and Exon microarray summarized to genes.

The BrainSpan atlas was developed by a consortium consisting of the Allen Institute for Brain Science; Yale University (Nenad Sestan, Mark B. Gerstein); the Zilkha Neurogenetic Institute of the Keck School of Medicine of the University of Southern California (James A. Knowles, Pat Levitt); the Athinoula A. Martinos Center at Massachusetts General Hospital/Harvard Medical School and MIT HST/CSAIL (Bruce Fischl); the University of California, Los Angeles (Daniel H. Geschwind); and the University of Texas Southwestern Medical Center (Hao Huang), with strong collaborative support from the Genes, Cognition and Psychosis Program, which is part of the Intramural Research Program of NIMH, NIH (Thomas M. Hyde, Joel E. Kleinman, Daniel R. Weinberger).
Other Name(s): BrainSpan - Atlas of the Developing Human Brain, NIMH Transcriptional Atlas of Human Brain Development
Parent Organization: Resource:Allen Institute for Brain Science
Supporting Agency: NIMH
Related to: Resource:NIH Blueprint NHP Atlas, Resource:Allen Developing Mouse Brain Atlas
Resource Type(s): Reference atlas, Expression atlas
Keywords: anatomic, gene expression, molecular neuroanatomy, in situ hybridization, human, medial prefrontal cortex, primary visual cortex, hippocampus, amygdala, ventral striatum, postnatal, development, brain development, transcription, brain, RNA Sequencing, exon microarray, developmental stage, male, female, mRNA transcript, developing human, adult human, fetal brain, Fetus, histology, transcriptome, magnetic resonance imaging, diffusion tensor imaging, annotation, neuroanatomy, prenatal, development, Fiber Tract, microarray, MRI, DTI, Methylation, MicroRNA, MRF
Grant: RC2MH089921, RC2MH090047, RC2MH089929
Abbreviation: BrainSpan
Resource: Resource
URL: http://brainspan.org/
Related condition/disease: neurodevelopmental disorder, neurological disease, neuropsychiatric disease, autism, schizophrenia, epilepsy, Parkinson's disease, Alzheimer's disease, Normal
Id: nif-0000-10626
Organism: Human
Link to OWL / RDF: Download this content as OWL/RDF

Parts of Resource:BrainSpan: Atlas of the Developing Human Brain

Curation status: Curated

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Notes

This page uses this default form:Resource

Alt URL: http://www.developinghumanbrain.org/

Contributors

Aarnaud, Ccdbuser, Jcachat, Memartone



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Facts about Resource:BrainSpan: Atlas of the Developing Human BrainRDF feed
AbbrevBrainSpan  +
CurationStatusuncurated  +
DefiningCitationhttp://brainspan.org/  +
DefinitionAn atlas of the developing human brain des An atlas of the developing human brain designed as a foundational resource for studying transcriptional mechanisms involved in human brain development. The atlas consists of a variety of data modalities and data mining tools.

Developmental Transcriptome: RNA sequencing and exon microarray data profiling up to sixteen cortical and subcortical structures across the full course of human brain development.

Prenatal LMD Microarray: High-resolution neuroanatomical transcriptional profiles of ~300 distinct structures spanning the entire brain for four midgestional prenatal specimens.

In Situ Hybridization (ISH): High-resolution in situ hybridization image data covering selected genes and brain regions in developing and adult human brain.

Reference Atlas: Full color, high-resolution anatomic reference atlases of prenatal (two stages) and adult human brain along with supporting histology, magnetic resonance imaging (MRI) and diffusion weighted imaging (DWI) data.

The NIF Data Federation currently indexes the 4 Developmental Transcriptome BrainSpan datasets: RNA-Seq exons, RNA-Seq exons summarized to genes, Exon microarray summarized to probe sets, and Exon microarray summarized to genes.

The BrainSpan atlas was developed by a consortium consisting of the Allen Institute for Brain Science; Yale University (Nenad Sestan, Mark B. Gerstein); the Zilkha Neurogenetic Institute of the Keck School of Medicine of the University of Southern California (James A. Knowles, Pat Levitt); the Athinoula A. Martinos Center at Massachusetts General Hospital/Harvard Medical School and MIT HST/CSAIL (Bruce Fischl); the University of California, Los Angeles (Daniel H. Geschwind); and the University of Texas Southwestern Medical Center (Hao Huang), with strong collaborative support from the Genes, Cognition and Psychosis Program, which is part of the Intramural Research Program of NIMH, NIH (Thomas M. Hyde, Joel E. Kleinman, Daniel R. Weinberger).
, Joel E. Kleinman, Daniel R. Weinberger).
ExampleImageBrainSpan - Atlas of the Developing Human Brain.PNG  +
GrantCategory:RC2MH089921   +, Category:RC2MH090047   +, and Category:RC2MH089929   +
Has default formThis property is a special property in this wiki.Resource  +
Has roleReference atlas  +, and Expression atlas  +
Idnif-0000-10626  +
Is part ofResource:Allen Institute for Brain Science  +
KeywordsAnatomic  +, Gene expression  +, Molecular neuroanatomy  +, In-situ hybridization  +, Human  +, Medial prefrontal cortex  +, Visual cortex primary  +, Hippocampus  +, Amygdala  +, Ventral striatum  +, Postnatal  +, Development  +, Brain development  +, Transcription  +, Brain  +, RNA Sequencing  +, Exon microarray  +, Developmental stage  +, Male  +, Female  +, MRNA transcript  +, Developing human  +, Adult human  +, Fetal brain  +, Fetus  +, Histology  +, Transcriptome  +, Magnetic resonance imaging  +, Diffusion tensor imaging  +, Annotation  +, Neuroanatomy  +, Prenatal  +, Fiber Tract  +, Microarray  +, Magnetic resonance imaging  +, Diffusion tensor imaging  +, Methylation  +, MicroRNA  +, and MRF  +
LabelResource:BrainSpan: Atlas of the Developing Human Brain  +
ModifiedDate13 December 2013  +
Page has default formThis property is a special property in this wiki.Resource  +
RelatedToResource:NIH Blueprint NHP Atlas  +, and Resource:Allen Developing Mouse Brain Atlas  +
Related diseaseNeurodevelopmental disorder  +, Neurological disease  +, Neuropsychiatric disease  +, Autistic Disorder  +, Schizophrenia  +, Epilepsy  +, Parkinsons disease  +, Alzheimers disease  +, and Normal  +
SpeciesHuman  +
SuperCategoryResource  +
Supporting AgencyNational Institute of Mental Health  +
SynonymBrainSpan - Atlas of the Developing Human Brain  +, and NIMH Transcriptional Atlas of Human Brain Development  +