arrow

From NeuroLex

Jump to: navigation, search



Resource:Case Comprehensive Cancer Center Biorepository and Tissue Processing Core Facility

Name: Resource:Case Comprehensive Cancer Center Biorepository and Tissue Processing Core Facility
Description: The Case Comprehensive Cancer Center's Biorepository and Tissue Processing Core Facility (BTPC) serves two primary functions: 1. To build an inventory of remnant human tissues, blood and other body fluids (collectively termed biospecimens) targeted towards cancer and other medical research, for later assignment to investigators; and 2. To provide long term, controlled storage of biospecimens for specific researchers.

These samples are for research purposes only and may not be used for clinical diagnosis or implantation into humans. Clinical information relating to the samples and donors are collected and maintained in a secure database. Samples and data are de-identified or de-linked before release to the researcher unless he/she has specific IRB approval to gain access to this information.

Remnant biospecimens are prospectively collected from surgical procedures, autopsies and clinical laboratories for the BTPC by the Human Tissue Procurement Facility (HTPF), which operates under UH-IRB Protocol 01-02-45. Blood and bone marrow specimens are collected for the BTPC by the Hematopoietic Stem Cell Core Facility (HSCC), which operates under UH-IRB Protocol 09-90-195.

The Division of Surgical Pathology at University Hospitals Case Medical Center (UHCMC) has clinical archives of paraffin blocks that can be made available through the BTPC for retrospective research studies under the approval of the Vice Chair for Clinical Affairs at UHCMC. Surgical Pathologists associated with the BTPC are responsible for determining which blocks can be made available and how much material can be removed from the blocks.

Types of Tissue Available

  • Malignant, benign, diseased, normal and normal human tissues
  • Normal adjacent tissues available paired with tumor specimens in many cases
  • Tissues are collected from over 50 anatomic sites
  • Frozen specimens, OCT-embedded and paraffin-embedded tissues
  • Large array of paraffin-embedded specimens from clinical archives of paraffin blocks and QC research blocks maintained by the HTPF
  • Peripheral blood and bone marrow samples from initial visits and follow-up procedures are processed to obtain serum and cell fractions for storage
  • No samples are collected from individuals with known infectious illnesses
  • Fetal biospecimens are not collected due to state and local statutes
Other Name(s): Case Western Biorepository, Biorepository and Tissue Processing Core Facility of the Case Comprehensive Cancer Center, Case Western Reserve University: Biorepository and Tissue Processing Core Facility, Case Western Biorepository and Tissue Processing Core Facility, Case Comprehensive Cancer Center Biorepository and Tissue Processing Core Facility, Case BTPC, CWRU BTPC, Case CCC BTPC, Case Comprehensive Cancer Center Biorepository Tissue Processing Core Facility, Biorepository Tissue Processing Core Facility, CWRU CCC Biorepository Tissue Processing Core Facility, Case CCC Biorepository Tissue Processing Core Facility
Abbreviation: BTPC
Parent Organization: Case Western Reserve University; Ohio; USA, Resource:Case Comprehensive Cancer Center, US Biobank
Grant: P30 CA43703
Resource Type(s): Tissue bank, Biomaterial supply resource, Database, Material storage repository
Resource: Resource
URL: http://cancer.case.edu/sharedresources/biorepository/
*Id: nlx_39515
Related to: Human
Keywords: Tissue, Blood, Body fluid, Bone marrow, Stem cell, Serum, Cell fraction, Paraffin block, Clinical data, Malignant tissue, Benign tissue, Diseased tissue, Normal tissue, Cancer, Control, Research, Frozen, OCT-embedded, Paraffin-embedded, Tumor, Paraffin, OCT
Link to OWL / RDF: Download this content as OWL/RDF

Curation status: Uncurated

This resource will be curated within 7 days.

For Resource Owners:
After the resource is curated, you may create a sitemap, which will help keep your registry description up-to-date and inform search engines about your resource.

Note: For a new resource, the website's URL must first be verified by a NIF curator before you may proceed.

Learn more about what NIF can do for your resource.
Proudly proclaim your inclusion in NIF by displaying the "Registered with NIF" button on your site. Please login to create the sitemap. (top right)

Notes

This page uses this default form:Resource

Contributors

Aarnaud, Akash, Ccdbuser, Zaidaziz



bookmark

*Note: Neurolex imports many terms and their ids from existing community ontologies, e.g., the Gene Ontology. Neurolex, however, is a dynamic site and any content beyond the identifier should not be presumed to reflect the content or views of the source ontology. Users should consult with the authoritative source for each ontology for current information.

Facts about Resource:Case Comprehensive Cancer Center Biorepository and Tissue Processing Core FacilityRDF feed
AbbrevBTPC  +
CommentAddress:Case Comprehensive Cancer Center, Wearn Building, Rm. 333, 11100 Euclid Avenue, Cleveland, Ohio 44106-5065 Phone: 216.844.8292
CurationStatuscurated  +
DefiningCitationhttp://cancer.case.edu/sharedresources/biorepository/  +
DefinitionThe Case Comprehensive Cancer Center's Bio The Case Comprehensive Cancer Center's Biorepository and Tissue Processing Core Facility (BTPC) serves two primary functions: 1. To build an inventory of remnant human tissues, blood and other body fluids (collectively termed biospecimens) targeted towards cancer and other medical research, for later assignment to investigators; and 2. To provide long term, controlled storage of biospecimens for specific researchers.

These samples are for research purposes only and may not be used for clinical diagnosis or implantation into humans. Clinical information relating to the samples and donors are collected and maintained in a secure database. Samples and data are de-identified or de-linked before release to the researcher unless he/she has specific IRB approval to gain access to this information.

Remnant biospecimens are prospectively collected from surgical procedures, autopsies and clinical laboratories for the BTPC by the Human Tissue Procurement Facility (HTPF), which operates under UH-IRB Protocol 01-02-45. Blood and bone marrow specimens are collected for the BTPC by the Hematopoietic Stem Cell Core Facility (HSCC), which operates under UH-IRB Protocol 09-90-195.

The Division of Surgical Pathology at University Hospitals Case Medical Center (UHCMC) has clinical archives of paraffin blocks that can be made available through the BTPC for retrospective research studies under the approval of the Vice Chair for Clinical Affairs at UHCMC. Surgical Pathologists associated with the BTPC are responsible for determining which blocks can be made available and how much material can be removed from the blocks.

Types of Tissue Available

  • Malignant, benign, diseased, normal and normal human tissues
  • Normal adjacent tissues available paired with tumor specimens in many cases
  • Tissues are collected from over 50 anatomic sites
  • Frozen specimens, OCT-embedded and paraffin-embedded tissues
  • Large array of paraffin-embedded specimens from clinical archives of paraffin blocks and QC research blocks maintained by the HTPF
  • Peripheral blood and bone marrow samples from initial visits and follow-up procedures are processed to obtain serum and cell fractions for storage
  • No samples are collected from individuals with known infectious illnesses
  • Fetal biospecimens are not collected due to state and local statutes collected due to state and local statutes
ExampleImageBTPC.PNG  +
GrantCategory:P30 CA43703   +
Has default formThis property is a special property in this wiki.Resource  +
Has roleTissue bank  +, Biomaterial supply resource  +, Database  +, and Material storage repository  +
Idnlx_39515  +
Is part ofCase Western Reserve University; Ohio; USA  +, Resource:Case Comprehensive Cancer Center  +, and US Biobank  +
KeywordsTissue  +, Blood  +, Body fluid  +, Bone marrow  +, Stem cell  +, Serum  +, Cell fraction  +, Paraffin block  +, Clinical data  +, Malignant tissue  +, Benign tissue  +, Diseased tissue  +, Normal tissue  +, Cancer  +, Control  +, Research  +, Frozen  +, OCT-embedded  +, Paraffin-embedded  +, Tumor  +, Paraffin  +, and OCT  +
LabelResource:Case Comprehensive Cancer Center Biorepository and Tissue Processing Core Facility  +
ModifiedDate11 January 2012  +
Page has default formThis property is a special property in this wiki.Resource  +
RelatedToHuman  +
SuperCategoryResource  +
SynonymCase Western Biorepository  +, Biorepository and Tissue Processing Core Facility of the Case Comprehensive Cancer Center  +, Case Western Reserve University: Biorepository and Tissue Processing Core Facility  +, Case Western Biorepository and Tissue Processing Core Facility  +, Case Comprehensive Cancer Center Biorepository and Tissue Processing Core Facility  +, Case BTPC  +, CWRU BTPC  +, Case CCC BTPC  +, Case Comprehensive Cancer Center Biorepository Tissue Processing Core Facility  +, Biorepository Tissue Processing Core Facility  +, CWRU CCC Biorepository Tissue Processing Core Facility  +, and Case CCC Biorepository Tissue Processing Core Facility  +