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Resource:Computational Neurobiology and Imaging Center

Name: Resource:Computational Neurobiology and Imaging Center
Description: Center to advance research and training in mathematical, computational and modern imaging approaches to understanding the brain and its functions. Software tools and associated reconstruction data produced in the center are available.

Researchers study the relationships between neural function and structure at levels ranging from the molecular and cellular, through network organization of the brain. This involves the development of new computational and analytic tools for imaging and visualization of 3-D neural morphology, from the gross topologic characteristics of the dendritic arbor to the fine structure of spines and their synapses. Numerical simulations of neural mechanisms based on these structural data are compared with in-vivo and in-vitro electrophysiological recordings.

The group also develops new theoretical and analytic approaches to exploring the function of neural models of working memory. The goal of this analytic work is to combine biophysically realistic models and simulations with reduced mathematical models that capture essential dynamical behaviors while reproducing the functionally important features of experimental data.

Research areas include: Imaging Studies, Volume Integration, Visualization Techniques, Medial Axis Extraction, Spine Detection and Classification, Applications of Rayburst, Analysis of Spatially Complex Structures, Computational Modeling, Mathematical and Analytic Studies
Abbreviation: CNIC
Parent Organization: Mount Sinai School of Medicine; New York; USA
Supporting Agency: Howard Hughes Medical Institute, NIDCD, NIA, NIMH
Resource Type(s): Topical portal, Data set, Software resource
Resource: Resource
URL: http://research.mssm.edu/cnic/
*Id: nif-0000-10200
Related to: Resource:NeuroMorpho.Org
Address: Mount Sinai School of Medicine, Box 1065, One Gustave L. Levy Place, New York, NY 10029, USA
Keywords: brain, confocal, in-vitro, in-vivo, microscopy, morphology, morphometric, multi-photon, neural, neural function, neuron, simulation, stack, structure, synapse, topologic, variable, vessel, visualization, image, Neuroscience, Neurobiology, reconstruction, Modeling, Spatial, Rayburst, Spine, Arbor, Visual, Tiling, Imaging
Organism: Mouse, Macaque
Link to OWL / RDF: Download this content as OWL/RDF

Curation status: Uncurated

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Alt. URL: http://www.mssm.edu/cnic/



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Facts about Resource:Computational Neurobiology and Imaging CenterRDF feed
AbbrevCNIC  +
AddressMount Sinai School of Medicine  +, Box 1065  +, One Gustave L. Levy Place  +, New York  +, NY 10029  +, and USA  +
CurationStatuscurated  +
DefiningCitationhttp://research.mssm.edu/cnic/  +
DefinitionCenter to advance research and training in Center to advance research and training in mathematical, computational and modern imaging approaches to understanding the brain and its functions. Software tools and associated reconstruction data produced in the center are available.

Researchers study the relationships between neural function and structure at levels ranging from the molecular and cellular, through network organization of the brain. This involves the development of new computational and analytic tools for imaging and visualization of 3-D neural morphology, from the gross topologic characteristics of the dendritic arbor to the fine structure of spines and their synapses. Numerical simulations of neural mechanisms based on these structural data are compared with in-vivo and in-vitro electrophysiological recordings.

The group also develops new theoretical and analytic approaches to exploring the function of neural models of working memory. The goal of this analytic work is to combine biophysically realistic models and simulations with reduced mathematical models that capture essential dynamical behaviors while reproducing the functionally important features of experimental data.

Research areas include: Imaging Studies, Volume Integration, Visualization Techniques, Medial Axis Extraction, Spine Detection and Classification, Applications of Rayburst, Analysis of Spatially Complex Structures, Computational Modeling, Mathematical and Analytic Studies
odeling, Mathematical and Analytic Studies
Has default formThis property is a special property in this wiki.Resource  +
Has roleTopical portal  +, Data set  +, and Software resource  +
Idnif-0000-10200  +
Is part ofMount Sinai School of Medicine; New York; USA  +
KeywordsBrain  +, Confocal  +, In-vitro  +, In-vivo  +, Microscopy  +, Morphology  +, Morphometric  +, Multi-photon  +, Neural  +, Neural function  +, Neuron  +, Simulation  +, Stack  +, Structure  +, Synapse  +, Topologic  +, Variable  +, Vessel  +, Visualization  +, Image  +, Neuroscience  +, Neurobiology  +, Reconstruction  +, Modeling  +, Spatial  +, Rayburst  +, Spine  +, Arbor  +, Visual  +, Tiling  +, and Imaging  +
LabelResource:Computational Neurobiology and Imaging Center  +
ModifiedDate9 June 2014  +
Page has default formThis property is a special property in this wiki.Resource  +
RelatedToResource:NeuroMorpho.Org  +
SpeciesMouse  +, and Macaque  +
SuperCategoryResource  +
Supporting AgencyHoward Hughes Medical Institute  +, NIDCD  +, NIA  +, and NIMH  +