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Resource:EchoBASE

Name: Resource:EchoBASE
Description: A database that curates new experimental and bioinformatic information about the genes and gene products of the model bacterium Escherichia coli K-12 strain MG1655. It has been created to integrate information from post-genomic experiments into a single resource with the aim of providing functional predictions for the 1500 or so gene products for which we have no knowledge of their physiological function.

While EchoBASE provides a basic annotation of the genome, taken from other databases, its novelty is in the curation of post-genomic experiments and their linkage to genes of unknown function. Experiments published on E. coli are curated to one of two levels. Papers dealing with the determination of function of a single gene are briefly described, while larger dataset are actually included in the database and can be searched and manipulated. This includes data for proteomics studies, protein-protein interaction studies, microarray data, functional genomic approaches (looking at multiple deletion strains for novel phenotypes) and a wide range of predictions that come out of in silico bioinformatic approaches.

The aim of the database is to provide hypothesis for the functions of uncharacterized gene products that may be used by the E. coli research community to further our knowledge of this model bacterium.
Other Name(s): EchoBASE: an integrated post-genomic database for Escherichia coli
Abbreviation: EchoBASE
Parent Organization: University of York; York; United Kingdom
Supporting Agency: Resource:GlaxoSmithKline, BBSRC
Resource Type(s): Database
Resource: Resource
URL: http://www.ecoli-york.org/
*Id: nif-0000-02781
PMID: PMID 15608209
Keywords: gene
Organism: Escherichia coli
Link to OWL / RDF: Download this content as OWL/RDF

Curation status: Curated

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Facts about Resource:EchoBASERDF feed
AbbrevEchoBASE  +
CurationStatuscurated  +
DefiningCitationhttp://www.ecoli-york.org/  +
DefinitionA database that curates new experimental a A database that curates new experimental and bioinformatic information about the genes and gene products of the model bacterium Escherichia coli K-12 strain MG1655. It has been created to integrate information from post-genomic experiments into a single resource with the aim of providing functional predictions for the 1500 or so gene products for which we have no knowledge of their physiological function.

While EchoBASE provides a basic annotation of the genome, taken from other databases, its novelty is in the curation of post-genomic experiments and their linkage to genes of unknown function. Experiments published on E. coli are curated to one of two levels. Papers dealing with the determination of function of a single gene are briefly described, while larger dataset are actually included in the database and can be searched and manipulated. This includes data for proteomics studies, protein-protein interaction studies, microarray data, functional genomic approaches (looking at multiple deletion strains for novel phenotypes) and a wide range of predictions that come out of in silico bioinformatic approaches.

The aim of the database is to provide hypothesis for the functions of uncharacterized gene products that may be used by the E. coli research community to further our knowledge of this model bacterium.
her our knowledge of this model bacterium.
ExampleImageEchoBASE.PNG  +
Has default formThis property is a special property in this wiki.Resource  +
Has roleDatabase  +
Idnif-0000-02781  +
Is part ofUniversity of York; York; United Kingdom  +
KeywordsGene  +
LabelResource:EchoBASE  +
ModifiedDate3 October 2014  +
PMID15608209  +
Page has default formThis property is a special property in this wiki.Resource  +
SpeciesEscherichia coli  +
SuperCategoryResource  +
Supporting AgencyResource:GlaxoSmithKline  +, and BBSRC  +
SynonymEchoBASE: an integrated post-genomic database for Escherichia coli  +