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Resource:Estonian Genome Center
| Name: | Resource:Estonian Genome Center |
| Description: | The Estonian Biobank is the population-based biobank of the EGCUT. The project is conducted in accordance with the Estonian Genes Research Act and all participants have signed a broad informed consent form (www.biobank.ee <http://www.biobank.ee/> and Metspalu 2004, Drug Dev. Res.). As of December 2011, the biobank contains 51,515 participants (gene donors). The database of genotypic, phenotypic, health and genealogical information represents about 5% of Estonia’s adult population, and is the largest cohort ever gathered in Estonia. The age, sex and geographical distribution of this cohort reflect the structure of the adult population in Estonia.
The database enables to conduct research in order to find links between genes, environmental factors, lifestyles and complex diseases or other traits. Active use of the biobank has started and although the first users are researchers all over the world with hundreds of different projects currently underway, industry is also interested. At the international level, the EGCUT will join the BBMRI follow-up program (ERIC) and through this channel provide service (biobanking, genotyping, sequencing and data analysis) for the centers in Europe who need it. Currently, the first follow-up study is underway and the molecular information of the cohort will be increased. For example, we have over 12 000 DNA samples analyzed by high density genotyping arrays and over 10 000 plasma samples analyzed by NMR scans, over 1000 individuals with RNA expression arrays, 2000 individuals with clinical laboratory analysis (over 40 tests) and over 60 full genomes are under deep sequencing. The infrastructure of the EGCUT includes a laboratory for DNA genotyping and next generation sequencing all based on Illumina platforms (HiScanSQ, HiSeq2000 and robotics), an IT unit (databases) with required computing power and storage space (1.2PB), data analysis team (bioinformatics and statistical genetics) and last but not least, a patient recruitment unit (health records, lifestyle and environmental information and biological samples – DNA, plasma and WBC from all 51515 gene donors). This is all located on 1000m2 in a brand new laboratory building, Riia str 23, Tartu, Estonia. |
| Other Name(s): | Estonian Genome Center University of Tartu, Estonian Biobank |
| Parent Organization: | University of Tartu; Tartu; Estonia, European Biobank |
| Related to: | Human, Resource:Biobanking and Biomolecular Resources Research Infrastructure (BBMRI) |
| Resource Type(s): | Biomaterial supply resource, Database, Data analysis service |
| Keywords: | Biomedicine, Population-based studies, Population-based study, Biobanking, Genotyping, Sequencing, Data analysis, WBC, Gene, Environmental factor, Disease, Genomics, Epidemiology, Clinical data, DNA, White blood cell, Plasma, Blood, Lifestyle, Demographic, Genetic |
| Abbreviation: | EGCUT, EGC |
| Resource: | Resource |
| URL: | http://www.geenivaramu.ee/en/ |
| Id: | nlx_45748 |
| Link to OWL / RDF: | Download this content as OWL/RDF |
Curation status: Uncurated
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Notes
This page uses this default form:Resource
Old URL: http://www.geenivaramu.ee/index.php?lang=eng
Alt URL: http://www.geenivaramu.ee/
| Abbrev | EGCUT, EGC + |
| Address | Tartu +, and Estonia Phone: +372 7 440 200 Fax: +372 7 440 221 + |
| Availability | Public: The anonymous data (and biological materials) of the gene donors are available for research projects. Before an application can be accepted for review +, The research project has to obtain an approval from the Ethics Review Committee on Human Research of the University of Tartu. The applicant will be asked to submit the results of the research project that were obtained using the data of the gene donors +, and To the EGCUT by the time specified in the contract. These results will complement the EGCUT database. + |
| Comment | Sample type: DNA, White blood cell, Plasma, Blood |
| CurationStatus | curated + |
| DefiningCitation | http://www.geenivaramu.ee/en/ + |
| Definition | The Estonian Biobank is the population-bas … The Estonian Biobank is the population-based biobank of the EGCUT. The project is conducted in accordance with the Estonian Genes Research Act and all participants have signed a broad informed consent form (www.biobank.ee <http://www.biobank.ee/> and Metspalu 2004, Drug Dev. Res.). As of December 2011, the biobank contains 51,515 participants (gene donors). The database of genotypic, phenotypic, health and genealogical information represents about 5% of Estonia’s adult population, and is the largest cohort ever gathered in Estonia. The age, sex and geographical distribution of this cohort reflect the structure of the adult population in Estonia.
The database enables to conduct research in order to find links between genes, environmental factors, lifestyles and complex diseases or other traits. Active use of the biobank has started and although the first users are researchers all over the world with hundreds of different projects currently underway, industry is also interested. At the international level, the EGCUT will join the BBMRI follow-up program (ERIC) and through this channel provide service (biobanking, genotyping, sequencing and data analysis) for the centers in Europe who need it. Currently, the first follow-up study is underway and the molecular information of the cohort will be increased. For example, we have over 12 000 DNA samples analyzed by high density genotyping arrays and over 10 000 plasma samples analyzed by NMR scans, over 1000 individuals with RNA expression arrays, 2000 individuals with clinical laboratory analysis (over 40 tests) and over 60 full genomes are under deep sequencing. The infrastructure of the EGCUT includes a laboratory for DNA genotyping and next generation sequencing all based on Illumina platforms (HiScanSQ, HiSeq2000 and robotics), an IT unit (databases) with required computing power and storage space (1.2PB), data analysis team (bioinformatics and statistical genetics) and last but not least, a patient recruitment unit (health records, lifestyle and environmental information and biological samples – DNA, plasma and WBC from all 51515 gene donors). This is all located on 1000m2 in a brand new laboratory building, Riia str 23, Tartu, Estonia. ry building, Riia str 23, Tartu, Estonia. |
| ExampleImage |  + |
| Has default formThis property is a special property in this wiki. | Resource + |
| Has role | Biomaterial supply resource +, Database +, and Data analysis service + |
| Id | nlx_45748 + |
| Is part of | University of Tartu; Tartu; Estonia + |
| Keywords | Biomedicine +, Population-based studies +, Population-based study +, Biobanking +, Genotyping +, Sequencing +, Data analysis +, WBC +, Gene +, Environmental factor +, Disease +, Genomics +, Epidemiology +, Clinical data +, DNA +, White blood cell +, Plasma +, Blood +, Lifestyle +, Demographic +, and Genetic + |
| Label | Resource:Estonian Genome Center + |
| ModifiedDate | 27 July 2012 + |
| Page has default formThis property is a special property in this wiki. | Resource + |
| RelatedTo | Resource:One Mind Biospecimen Bank Listing +, and European Biobank + |
| Related application | Research + |
| Related disease | General population + |
| Species | Human + |
| SuperCategory | Resource + |
| Synonym | Estonian Genome Center University of Tartu +, and Estonian Biobank + |
