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Resource:GeneDB Spombe

Name: Resource:GeneDB Spombe
Description: THIS RESOURCE IS NO LONGER IN SERVICE documented June 6, 2013

Database of all S. pombe (fission yeast) known and predicted protein coding genes, pseudogenes, transposons, tRNAs, rRNAs, snRNAs, snoRNAs and other known and predicted non-coding RNAs. Curation of new and existing literature is ongoing and changes are incorporated weekly. User feedback is welcome.

The genome of fission yeast (Schizosaccharomyces pombe), which contains the smallest number of protein-coding genes yet recorded for a eukaryote: 4,824, has been sequenced and annotated. The centromeres are between 35 and 110 kilobases (kb) and contain related repeats including a highly conserved 1.8-kb element. Regions upstream of genes are longer than in budding yeast (Saccharomyces cerevisiae), possibly reflecting more-extended control regions. Some 43% of the genes contain introns, of which there are 4,730. Fifty genes have significant similarity with human disease genes; half of these are cancer related. We identify highly conserved genes important for eukaryotic cell organization including those required for the cytoskeleton, compartmentation, cell-cycle control, proteolysis, protein phosphorylation and RNA splicing. These genes may have originated with the appearance of eukaryotic life. Few similarly conserved genes that are important for multicellular organization were identified, suggesting that the transition from prokaryotes to eukaryotes required more new genes than did the transition from unicellular to multicellular organization.
Other Name(s): Schizosaccharomyces pombe GeneDB, GDB S. pombe
Parent Organization: Resource:GeneDB
Supporting Agency: Wellcome Trust
Related to: Resource:PomBase
Resource Type(s): Database
Keywords: Fission yeast
Abbreviation: GeneDB_Spombe, GeneDB Spombe, GeneDB S. pombe
Resource: Resource
URL: http://old.genedb.org/genedb/pombe/index.jsp
PMID: PMID 11859360
Availability: THIS RESOURCE IS NO LONGER IN SERVICE, documented June 6, 2013
Id: nlx_62442
Organism: Schizosaccharomyces pombe
Link to OWL / RDF: Download this content as OWL/RDF

Curation status: Curated

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Notes

This page uses this default form:Resource

Contributors

Aarnaud, Akash, Memartone



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Facts about Resource:GeneDB SpombeRDF feed
AbbrevGeneDB_Spombe, GeneDB Spombe, GeneDB S. pombe  +
AvailabilityTHIS RESOURCE IS NO LONGER IN SERVICE  +, Documented June 6  +, and 2013  +
CommentAccording to the pombase.org website, this resource is no longer available after May 14, 2013. The URL redirects to http://pombase.org.
CurationStatusuncurated  +
DefiningCitationhttp://old.genedb.org/genedb/pombe/index.jsp  +
DefinitionTHIS RESOURCE IS NO LONGER IN SERVICE docu THIS RESOURCE IS NO LONGER IN SERVICE documented June 6, 2013

Database of all S. pombe (fission yeast) known and predicted protein coding genes, pseudogenes, transposons, tRNAs, rRNAs, snRNAs, snoRNAs and other known and predicted non-coding RNAs. Curation of new and existing literature is ongoing and changes are incorporated weekly. User feedback is welcome.

The genome of fission yeast (Schizosaccharomyces pombe), which contains the smallest number of protein-coding genes yet recorded for a eukaryote: 4,824, has been sequenced and annotated. The centromeres are between 35 and 110 kilobases (kb) and contain related repeats including a highly conserved 1.8-kb element. Regions upstream of genes are longer than in budding yeast (Saccharomyces cerevisiae), possibly reflecting more-extended control regions. Some 43% of the genes contain introns, of which there are 4,730. Fifty genes have significant similarity with human disease genes; half of these are cancer related. We identify highly conserved genes important for eukaryotic cell organization including those required for the cytoskeleton, compartmentation, cell-cycle control, proteolysis, protein phosphorylation and RNA splicing. These genes may have originated with the appearance of eukaryotic life. Few similarly conserved genes that are important for multicellular organization were identified, suggesting that the transition from prokaryotes to eukaryotes required more new genes than did the transition from unicellular to multicellular organization.
unicellular to multicellular organization.
ExampleImageGeneDB Spombe.PNG  +
Has default formThis property is a special property in this wiki.Resource  +
Has roleDatabase  +
Idnlx_62442  +
Is part ofResource:GeneDB  +
KeywordsFission yeast  +
LabelResource:GeneDB Spombe  +
ModifiedDate28 June 2013  +
PMID11859360  +
Page has default formThis property is a special property in this wiki.Resource  +
RelatedToResource:PomBase  +
SpeciesSchizosaccharomyces pombe  +
SuperCategoryResource  +
Supporting AgencyWellcome Trust  +
SynonymSchizosaccharomyces pombe GeneDB  +, and GDB S. pombe  +