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Resource:NIH Clinical Collection

Name: Resource:NIH Clinical Collection
Description: A plated array of approximately 450 small molecules that have a history of use in human clinical trials. The collection was assembled by the National Institutes of Health (NIH) through the Molecular Libraries Roadmap Initiative as part of its mission to enable the use of compound screens in biomedical research. Similar collections of FDA approved drugs have proven to be rich sources of undiscovered bioactivity and therapeutic potential. The clinically tested compounds in the NCC are highly drug-like with known safety profiles. These compounds can provide excellent starting points for medicinal chemistry optimization and, for high-affinity targets, may even be appropriate for direct human use in new disease areas.
Abbreviation: NCC
Parent Organization: BioFocus
Supporting Agency: National Institutes of Health
Resource Type(s): Reagent supplier, Material resource
Resource: Resource
URL: http://www.nihclinicalcollection.com
Id: nif-0000-00254
Related to: Molecular Libraries Roadmap Initiative
Keywords: Clinical, Collection, Drug, Compound, Chemistry, Medicinal chemistry, Target, Affinity, Human, Disease, Disorder, small molecule
Link to OWL / RDF: Download this content as OWL/RDF

Curation status: Uncurated

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Notes

This page uses this default form:Resource

Contributors

Aarnaud, Ccdbuser, Memartone, Nifbot2



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Facts about Resource:NIH Clinical CollectionRDF feed
AbbrevNCC  +
CurationStatusuncurated  +
DefiningCitationhttp://www.nihclinicalcollection.com  +
DefinitionA plated array of approximately 450 small A plated array of approximately 450 small molecules that have a history of use in human clinical trials. The collection was assembled by the National Institutes of Health (NIH) through the Molecular Libraries Roadmap Initiative as part of its mission to enable the use of compound screens in biomedical research. Similar collections of FDA approved drugs have proven to be rich sources of undiscovered bioactivity and therapeutic potential. The clinically tested compounds in the NCC are highly drug-like with known safety profiles. These compounds can provide excellent starting points for medicinal chemistry optimization and, for high-affinity targets, may even be appropriate for direct human use in new disease areas. for direct human use in new disease areas.
Has default formThis property is a special property in this wiki.Resource  +
Has roleReagent supplier  +, and Material resource  +
Idnif-0000-00254  +
Is part ofBioFocus  +
KeywordsClinical  +, Collection  +, Drug  +, Compound  +, Chemistry  +, Medicinal chemistry  +, Target  +, Affinity  +, Human  +, Disease  +, Disorder  +, and Small molecule  +
LabelResource:NIH Clinical Collection  +
ModifiedDate26 January 2013  +
Page has default formThis property is a special property in this wiki.Resource  +
RelatedToMolecular Libraries Roadmap Initiative  +
SuperCategoryResource  +
Supporting AgencyNational Institutes of Health  +