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Resource:NIH Clinical Collection
| Name: | Resource:NIH Clinical Collection |
| Description: | A plated array of approximately 450 small molecules that have a history of use in human clinical trials. The collection was assembled by the National Institutes of Health (NIH) through the Molecular Libraries Roadmap Initiative as part of its mission to enable the use of compound screens in biomedical research. Similar collections of FDA approved drugs have proven to be rich sources of undiscovered bioactivity and therapeutic potential. The clinically tested compounds in the NCC are highly drug-like with known safety profiles. These compounds can provide excellent starting points for medicinal chemistry optimization and, for high-affinity targets, may even be appropriate for direct human use in new disease areas. |
| Parent Organization: | BioFocus |
| Supporting Agency: | National Institutes of Health |
| Related to: | Molecular Libraries Roadmap Initiative |
| Resource Type(s): | Reagent supplier, Material resource |
| Keywords: | Clinical, Collection, Drug, Compound, Chemistry, Medicinal chemistry, Target, Affinity, Human, Disease, Disorder, small molecule |
| Abbreviation: | NCC |
| Resource: | Resource |
| URL: | http://www.nihclinicalcollection.com |
| Id: | nif-0000-00254 |
| Link to OWL / RDF: | Download this content as OWL/RDF |
Curation status: Curated
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Facts about Resource:NIH Clinical CollectionRDF feed
| Abbrev | NCC + |
| CurationStatus | uncurated + |
| DefiningCitation | http://www.nihclinicalcollection.com + |
| Definition | A plated array of approximately 450 small … A plated array of approximately 450 small molecules that have a history of use in human clinical trials. The collection was assembled by the National Institutes of Health (NIH) through the Molecular Libraries Roadmap Initiative as part of its mission to enable the use of compound screens in biomedical research. Similar collections of FDA approved drugs have proven to be rich sources of undiscovered bioactivity and therapeutic potential. The clinically tested compounds in the NCC are highly drug-like with known safety profiles. These compounds can provide excellent starting points for medicinal chemistry optimization and, for high-affinity targets, may even be appropriate for direct human use in new disease areas. for direct human use in new disease areas. |
| Has default formThis property is a special property in this wiki. | Resource + |
| Has role | Reagent supplier +, and Material resource + |
| Id | nif-0000-00254 + |
| Is part of | BioFocus + |
| Keywords | Clinical +, Collection +, Drug +, Compound +, Chemistry +, Medicinal chemistry +, Target +, Affinity +, Human +, Disease +, Disorder +, and Small molecule + |
| Label | Resource:NIH Clinical Collection + |
| ModifiedDate | 26 January 2013 + |
| Page has default formThis property is a special property in this wiki. | Resource + |
| RelatedTo | Molecular Libraries Roadmap Initiative + |
| SuperCategory | Resource + |
| Supporting Agency | National Institutes of Health + |