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Resource:Psychoactive Drug Screening Program Ki Database
| Name: | Resource:Psychoactive Drug Screening Program Ki Database |
| Description: | The PDSP Ki database is a unique resource in the public domain which provides information on the abilities of drugs to interact with an expanding number of molecular targets.
The Ki database serves as a data warehouse for published and internally-derived Ki, or affinity, values for a large number of drugs and drug candidates at an expanding number of G-protein coupled receptors, ion channels, transporters and enzymes. The query interface is designed to let you search by any field, or combination of them to refine your search criteria. The flexible user interface also provides for customized data mining. Our database is regularly updated. If you know of Ki data you would like us to add, you can select Direct Ki Entry at the grey panel. If you would like, however, your own data (published or not) added, Send Us a Reference at the grey panel, or send an email to Dr. Bryan Roth or Estela Lopez. Most common targets: 5-HT2A, DOPAMINE D1, DOPAMINE D2, 5-HT2C, 5-HT1A, Cholinergic, muscarinic M1, 5-HT Transporter, HISTAMINE H1, 5-HT2B, OPIOID Mu, 5-HT6, adrenergic Beta2, 5-HT7, OPIATE Delta, adrenergic Alpha1A, OPIOID Kappa, 5-HT3, m-AChR, adrenergic Beta1, adrenergic Alpha2A, 5-HT1, Acetylcholinesterase, AChE, Thromboxane A2, n-AChR, Opiate non-selective, CANNABINOID CB1, HERG, Dopamine, cocaine site, adrenergic Alpha2C, M3, Norepinephrine Uptake, Monoamine Oxidase A, Monoamine Oxidase B, 5-HT4, adrenergic Alpha1, 5-HT1E, B1 BRADYKININ, 5-HT2, 5-HT2C-INI, DOPAMINE D4, ANGIOTENSIN AT1, Neurokinin NK1, HISTAMINE H3, Sigma-1, VIP, Dopamine2-like, metabotropic glutamate 5, 5-HT2c VGI, Carbonic Anhydrase Isozymes, CA I, DOPAMINE D2 Long, adrenergic Alpha2, adrenergic Alpha2B, adrenergic Alpha2D, GABA A alpha1, CANNABINOID CB2, adrenergic Alpha1B, 5-HT5a, Melatonin, HISTAMINE H4, NMDA, 5-HT4a, Glucocorticoid, Interleukin 1-beta, Sodium Channel, Benzodiazepine central, Cholinergic, muscarinic M5, Neuropeptide Y1, GABA A alpha5, Galanin R2, Neurokinin NK3, 5-HT1B, M2, DOPAMINE D3, Angiotensin, Dopamine1-like, Neurokinin NK2, adrenergic Beta, Dopamine D1 high, Dopamine D1A, MAP kinase, ADENOSINE A2a, 5-HT7b, Nitrogen oxide synthase - neuronal, Sigma-2, CDK2, Neurotensin 2, DOPAMINE D2 Short, Multidrug Resistance Transporter MDR 1, GABA A Benzodiazepine, VEGF-R2, OPIATE Mu 2, Angiotensin II AT1, HISTAMINE H2, Angiotensin-converting enzyme, ACE, Sigma, beta-amyloid, ADENOSINE, ADENOSINE A2B, Adrenaline, Neurotensin 1 |
| Other Name(s): | PDSP Ki Database, Ki Database |
| Parent Organization: | University of North Carolina at Chapel Hill; North Carolina; USA |
| Supporting Agency: | NIMH, Heffter Research Institute |
| Related to: | NIF Data Federation |
| Resource Type(s): | Database, Data storage repository |
| Keywords: | GPCR, Ki, 5-HT Transporter, 5-HT2A, DOPAMINE D2, DOPAMINE D1, 5-HT1A, M1, Dopamine Transporter, OPIATE Mu, HISTAMINE H1, adrenergic Alpha1, 5-HT7, M2, 5-HT2C, CANNABINOID CB1, adrenergic Alpha2A, NET, 5-HT3, 5-HT2B, adrenergic Alpha1A, adrenergic Beta1 |
| Abbreviation: | Ki DB |
| Resource: | Resource |
| URL: | http://pdsp.med.unc.edu/pdsp.php |
| Id: | nif-0000-01866 |
| Link to OWL / RDF: | Download this content as OWL/RDF |
Curation status: Curated
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| Abbrev | Ki DB + |
| CurationStatus | curated + |
| DefiningCitation | http://pdsp.med.unc.edu/pdsp.php + |
| Definition | The PDSP Ki database is a unique resource … The PDSP Ki database is a unique resource in the public domain which provides information on the abilities of drugs to interact with an expanding number of molecular targets.
The Ki database serves as a data warehouse for published and internally-derived Ki, or affinity, values for a large number of drugs and drug candidates at an expanding number of G-protein coupled receptors, ion channels, transporters and enzymes. The query interface is designed to let you search by any field, or combination of them to refine your search criteria. The flexible user interface also provides for customized data mining. Our database is regularly updated. If you know of Ki data you would like us to add, you can select Direct Ki Entry at the grey panel. If you would like, however, your own data (published or not) added, Send Us a Reference at the grey panel, or send an email to Dr. Bryan Roth or Estela Lopez. Most common targets: 5-HT2A, DOPAMINE D1, DOPAMINE D2, 5-HT2C, 5-HT1A, Cholinergic, muscarinic M1, 5-HT Transporter, HISTAMINE H1, 5-HT2B, OPIOID Mu, 5-HT6, adrenergic Beta2, 5-HT7, OPIATE Delta, adrenergic Alpha1A, OPIOID Kappa, 5-HT3, m-AChR, adrenergic Beta1, adrenergic Alpha2A, 5-HT1, Acetylcholinesterase, AChE, Thromboxane A2, n-AChR, Opiate non-selective, CANNABINOID CB1, HERG, Dopamine, cocaine site, adrenergic Alpha2C, M3, Norepinephrine Uptake, Monoamine Oxidase A, Monoamine Oxidase B, 5-HT4, adrenergic Alpha1, 5-HT1E, B1 BRADYKININ, 5-HT2, 5-HT2C-INI, DOPAMINE D4, ANGIOTENSIN AT1, Neurokinin NK1, HISTAMINE H3, Sigma-1, VIP, Dopamine2-like, metabotropic glutamate 5, 5-HT2c VGI, Carbonic Anhydrase Isozymes, CA I, DOPAMINE D2 Long, adrenergic Alpha2, adrenergic Alpha2B, adrenergic Alpha2D, GABA A alpha1, CANNABINOID CB2, adrenergic Alpha1B, 5-HT5a, Melatonin, HISTAMINE H4, NMDA, 5-HT4a, Glucocorticoid, Interleukin 1-beta, Sodium Channel, Benzodiazepine central, Cholinergic, muscarinic M5, Neuropeptide Y1, GABA A alpha5, Galanin R2, Neurokinin NK3, 5-HT1B, M2, DOPAMINE D3, Angiotensin, Dopamine1-like, Neurokinin NK2, adrenergic Beta, Dopamine D1 high, Dopamine D1A, MAP kinase, ADENOSINE A2a, 5-HT7b, Nitrogen oxide synthase - neuronal, Sigma-2, CDK2, Neurotensin 2, DOPAMINE D2 Short, Multidrug Resistance Transporter MDR 1, GABA A Benzodiazepine, VEGF-R2, OPIATE Mu 2, Angiotensin II AT1, HISTAMINE H2, Angiotensin-converting enzyme, ACE, Sigma, beta-amyloid, ADENOSINE, ADENOSINE A2B, Adrenaline, Neurotensin 1 , ADENOSINE A2B, Adrenaline, Neurotensin 1 |
| ExampleImage |  + |
| Has default formThis property is a special property in this wiki. | Resource + |
| Has role | Database +, and Data storage repository + |
| Id | nif-0000-01866 + |
| Is part of | University of North Carolina at Chapel Hill; North Carolina; USA + |
| Keywords | GPCR +, Ki +, 5-HT Transporter +, 5-HT2A +, DOPAMINE D2 +, DOPAMINE D1 +, 5-HT1A +, M1 +, Dopamine Transporter +, OPIATE Mu +, HISTAMINE H1 +, Adrenergic Alpha1 +, 5-HT7 +, M2 +, 5-HT2C +, CANNABINOID CB1 +, Adrenergic Alpha2A +, NET +, 5-HT3 +, 5-HT2B +, Adrenergic Alpha1A +, and Adrenergic Beta1 + |
| Label | Resource:Psychoactive Drug Screening Program Ki Database + |
| ModifiedDate | 23 April 2012 + |
| Page has default formThis property is a special property in this wiki. | Resource + |
| RelatedTo | NIF Data Federation + |
| Supporting Agency | National Institute of Mental Health +, and Heffter Research Institute + |
| Synonym | PDSP Ki Database +, and Ki Database + |
